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The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

Immunity (Cambridge, Mass.), 2011-05, Vol.34 (5), p.769-780

2011

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Tumor-immune profiling of CT-26 and Colon 26 syngeneic mouse models reveals mechanism of anti-PD-1 response

BMC cancer, 2021-11, Vol.21 (1), p.1222-1222, Article 1222

2021

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NOD-like receptors: role in innate immunity and inflammatory disease

Annual review of pathology, 2009-02, Vol.4 (1), p.365-398

2009

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The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (24), p.10060-10067

2008

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The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

Immunity (Cambridge, Mass.), 2008-02, Vol.28 (2), p.246-257

2008

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Fc-independent functions of anti-CTLA-4 antibodies contribute to anti-tumor efficacy

Cancer Immunology, Immunotherapy, 2022-10, Vol.71 (10), p.2421-2431

2022

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Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

The Journal of experimental medicine, 2006-09, Vol.203 (9), p.2063-2071

2006

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Intracellular NOD-like receptors in innate immunity, infection and disease

Cellular microbiology, 2008-01, Vol.10 (1), p.1-8

2008

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Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome

European journal of immunology, 2010-03, Vol.40 (3), p.764-769

2010

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NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

Nature immunology, 2012-05, Vol.13 (5), p.449

2012

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Signal conversion as tumor micro environment (TME) specifically activated cytokine

Biochemical and biophysical research communications, 2023-11, Vol.683, p.149077-149077, Article 149077

2023

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TLR3 Signaling Promotes the Induction of Unique Human BDCA-3 Dendritic Cell Populations

Frontiers in immunology, 2016-03, Vol.7, p.88-88

2016

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Microbiota-dependent activation of CD4 + T cells induces CTLA-4 blockade-associated colitis via Fcγ receptors

Science (American Association for the Advancement of Science), 2024-01, Vol.383 (6678), p.62-70

2024

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NOD-like receptors (NLRs): bona fide intracellular microbial sensors

Current opinion in immunology, 2008-08, Vol.20 (4), p.377-382

2008

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A Natural Mutation in the Tyk2 Pseudokinase Domain Underlies Altered Susceptibility of B10.Q/J Mice to Infection and Autoimmunity

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11594-11599

2003

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T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

Nature immunology, 2009-12, Vol.10 (12), p.1267-1274

2009

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The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation

Trends in immunology, 2011-02, Vol.32 (2), p.73-79

2011

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Cutting edge: Crohn's disease-associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality

The Journal of immunology (1950), 2011-09, Vol.187 (6), p.2849-2852

2011

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Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation

Journal of Immunology, 2006-06, Vol.176 (12), p.7263-7271

2006

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TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies

Cancer research communications, 2022-06, Vol.2 (6), p.489-502

2022

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Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

The Journal of experimental medicine, 2012-02, Vol.209 (2), p.251-258

2012

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Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection

Microbes and infection, 2006-04, Vol.8 (4), p.1174-1178

2006

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Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

The Journal of cell biology, 2006-09, Vol.174 (6), p.i11-i11

2006

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Abstract 3448: The IV STING agonist, TAK-676, enhances immune-mediated anti-tumor activity of radiation in syngeneic mouse models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3448-3448

2022

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Abstract CT243: Phase 1 study of TAK-676 + pembrolizumab following radiation therapy in patients with advanced non-small-cell lung cancer (NSCLC), triple-negative breast cancer (TNBC), or squamous-cell carcinoma of the head and neck (SCCHN)

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.CT243-CT243

2022

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The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

Tumor-immune profiling of CT-26 and Colon 26 syngeneic mouse models reveals mechanism of anti-PD-1 response

NOD-like receptors: role in innate immunity and inflammatory disease

The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis

The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

Fc-independent functions of anti-CTLA-4 antibodies contribute to anti-tumor efficacy

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

Intracellular NOD-like receptors in innate immunity, infection and disease

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

Signal conversion as tumor micro environment (TME) specifically activated cytokine

TLR3 Signaling Promotes the Induction of Unique Human BDCA-3 Dendritic Cell Populations

Microbiota-dependent activation of CD4 + T cells induces CTLA-4 blockade-associated colitis via Fcγ receptors

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

A Natural Mutation in the Tyk2 Pseudokinase Domain Underlies Altered Susceptibility of B10.Q/J Mice to Infection and Autoimmunity

T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation

Cutting edge: Crohn's disease-associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality

Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation

TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

Abstract 3448: The IV STING agonist, TAK-676, enhances immune-mediated anti-tumor activity of radiation in syngeneic mouse models

Abstract CT243: Phase 1 study of TAK-676 + pembrolizumab following radiation therapy in patients with advanced non-small-cell lung cancer (NSCLC), triple-negative breast cancer (TNBC), or squamous-cell carcinoma of the head and neck (SCCHN)

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