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Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension

Journal of medicinal chemistry, 2023-06, Vol.66 (12), p.8130-8139

2023

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Interactions between β2-Adrenoceptor Ligands and Membrane: Atomic-Level Insights from Magic-Angle Spinning NMR

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.6867-6879

2017

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Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.7901-7914

2016

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4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.280-284

2006

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2-Aryl indole NK1 receptor antagonists : Optimisation of indole substitution

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (9), p.1233-1236

2001

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Two Contrasting Asymmetric Approaches to Muscarine Based on 5-endo-trig Cyclisations

European journal of organic chemistry, 2004-05, Vol.2004 (9), p.1973-1982

2004

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4,4-Disubstituted cyclohexylamine NK1 receptor antagonists I

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (13), p.1755-1758

2002

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On the stereoselection of iodolactonizations of 3-silyloxyalk-5-enoic acids

Journal of the Chemical Society, Perkin Transactions 1, 1996-07 (13), p.1505

1996

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A radical cyclisation approach to the 2-oxabicyclo[2.2.1]heptane ring system

Journal of the Chemical Society. Chemical communications, 1994 (21), p.2447

1994

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4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (13), p.1755

2002

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4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists I

Bioorganic & medicinal chemistry letters, 2002, Vol.12 (13), p.1755-1758

2002

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Model studies of the overall 5-endo-trig iodocyclization of homoallylic alcohols

Journal of the Chemical Society, Perkin Transactions 1, 1999 (15), p.2143-2154

1999

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2-Aryl Indole NK 1 receptor antagonists: optimisation of indole substitution

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (9), p.1233-1236

2001

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ChemInform Abstract: Model Studies of the Overall 5-endo-trig Iodocyclization of Homoallylic Alcohols

ChemInform, 1999-11, Vol.30 (44), p.no-no

1999

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Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage

PloS one, 2010-10, Vol.5 (10), p.e13246-e13246

2010

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Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults

The New England journal of medicine, 2023-12, Vol.389 (24), p.2233-2244

2023

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Adaptation to culture of human embryonic stem cells and oncogenesis in vivo

Nature biotechnology, 2007-02, Vol.25 (2), p.207-215

2007

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Secondary solid cancer screening following hematopoietic cell transplantation

Bone marrow transplantation (Basingstoke), 2015-08, Vol.50 (8), p.1013-1023

2015

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Prediction of cardiovascular death and non-fatal cardiovascular events by the Kidney age–Chronological age Difference (KCD) score in men and women of different ages in a community-based cohort

BMJ open, 2023-03, Vol.13 (3), p.e068494-e068494

2023

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Ectopic pregnancy as a model to identify endometrial genes and signaling pathways important in decidualization and regulated by local trophoblast

PloS one, 2011-08, Vol.6 (8), p.e23595-e23595

2011

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Phylogenetic analyses allow species-level recognition of Leptographium wageneri varieties that cause black stain root disease of conifers in western North America

Frontiers in plant science, 2023-12, Vol.14, p.1286157-1286157

2023

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Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation

Bone marrow transplantation (Basingstoke), 2018-10, Vol.53 (10), p.1278-1287

2018

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Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)

The Lancet (British edition), 2021-09, Vol.398 (10304), p.981-990

2021

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Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21

The Lancet (British edition), 2022-04, Vol.399 (10334), p.1513-1536

2022

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Asymptomatic Visceral Leishmania infantum Infection in US Soldiers Deployed to Iraq

Clinical infectious diseases, 2019-05, Vol.68 (12), p.2036-2044

2019

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Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension

Interactions between β2-Adrenoceptor Ligands and Membrane: Atomic-Level Insights from Magic-Angle Spinning NMR

Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

2-Aryl indole NK1 receptor antagonists : Optimisation of indole substitution

Two Contrasting Asymmetric Approaches to Muscarine Based on 5-endo-trig Cyclisations

4,4-Disubstituted cyclohexylamine NK1 receptor antagonists I

On the stereoselection of iodolactonizations of 3-silyloxyalk-5-enoic acids

A radical cyclisation approach to the 2-oxabicyclo[2.2.1]heptane ring system

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I

4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists I

Model studies of the overall 5-endo-trig iodocyclization of homoallylic alcohols

2-Aryl Indole NK 1 receptor antagonists: optimisation of indole substitution

ChemInform Abstract: Model Studies of the Overall 5-endo-trig Iodocyclization of Homoallylic Alcohols

Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage

Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults

Adaptation to culture of human embryonic stem cells and oncogenesis in vivo

Secondary solid cancer screening following hematopoietic cell transplantation

Prediction of cardiovascular death and non-fatal cardiovascular events by the Kidney age–Chronological age Difference (KCD) score in men and women of different ages in a community-based cohort

Ectopic pregnancy as a model to identify endometrial genes and signaling pathways important in decidualization and regulated by local trophoblast

Phylogenetic analyses allow species-level recognition of Leptographium wageneri varieties that cause black stain root disease of conifers in western North America

Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation

Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21

Asymptomatic Visceral Leishmania infantum Infection in US Soldiers Deployed to Iraq

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