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Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry

Angewandte Chemie International Edition, 2014-09, Vol.53 (36), p.9430-9448

International ed. in English, 2014

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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18808-18814

2019

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SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization

Journal of the American Chemical Society, 2018-02, Vol.140 (8), p.2919-2925

2018

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A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope

Angewandte Chemie International Edition, 2018-03, Vol.57 (10), p.2605-2610

International ed. in English, 2018

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SuFExable polymers with helical structures derived from thionyl tetrafluoride

Nature chemistry, 2021-09, Vol.13 (9), p.858-867

2021

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SuFEx‐Based Polysulfonate Formation from Ethenesulfonyl Fluoride–Amine Adducts

Angewandte Chemie (International ed.), 2017-09, Vol.56 (37), p.11203-11208

International ed. in English, 2017

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Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery

Nature chemistry, 2020-10, Vol.12 (10), p.906-913

2020

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Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins

Angewandte Chemie International Edition, 2019-06, Vol.58 (24), p.8029-8033

International ed. in English, 2019

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Copper(I)‐Catalyzed Cycloaddition of Organic Azides and 1‐Iodoalkynes

Angewandte Chemie International Edition, 2009-01, Vol.48 (43), p.8018-8021

2009

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Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs

Angewandte Chemie International Edition, 2020-07, Vol.59 (30), p.12460-12469

International ed. in English, 2020

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Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

Nature communications, 2019-04, Vol.10 (1), p.1799-11, Article 1799

2019

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Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure

The Journal of pharmacology and experimental therapeutics, 2018-11, Vol.367 (2), p.363-372

2018

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SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues

Bioorganic & medicinal chemistry, 2024-04, Vol.104, p.117699-117699, Article 117699

2024

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Copper-Catalyzed Synthesis of N-Sulfonyl-1,2,3-triazoles: Controlling Selectivity

Angewandte Chemie International Edition, 2007-01, Vol.46 (10), p.1730-1733

2007

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Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates

Journal of the American Chemical Society, 2005-01, Vol.127 (1), p.210-216

2005

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Efficient Synthesis of 2-Substituted-1,2,3-triazoles

Organic letters, 2008-08, Vol.10 (15), p.3171-3174

2008

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Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms

Chemistry : a European journal, 2018-07, Vol.24 (41), p.10550-10556

2018

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A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective "Ligation" of Azides and Terminal Alkynes

Angewandte Chemie International Edition, 2002-07, Vol.41 (14), p.2596-2599

2002

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Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides

Journal of the American Chemical Society, 2005-11, Vol.127 (46), p.15998-15999

2005

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Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

Angewandte Chemie International Edition, 2004-07, Vol.43 (30), p.3928-3932

2004

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Bioconjugation by Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

Journal of the American Chemical Society, 2003-03, Vol.125 (11), p.3192-3193

2003

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A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans

Journal of the American Chemical Society, 2015-06, Vol.137 (23), p.7404-7414

2015

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A Sulfilimine Bond Identified in Collagen IV

Science (American Association for the Advancement of Science), 2009-09, Vol.325 (5945), p.1230-1234

2009

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Mechanistic Studies on the Cu-Catalyzed Three-Component Reactions of Sulfonyl Azides, 1-Alkynes and Amines, Alcohols, or Water: Dichotomy via a Common Pathway

Journal of organic chemistry, 2008-07, Vol.73 (14), p.5520-5528

2008

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Iterative In Situ Click Chemistry Creates Antibody-like Protein-Capture Agents

Angewandte Chemie (International ed.), 2009-01, Vol.48 (27), p.4944-4948

2009

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Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry

SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization

A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope

SuFExable polymers with helical structures derived from thionyl tetrafluoride

SuFEx‐Based Polysulfonate Formation from Ethenesulfonyl Fluoride–Amine Adducts

Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery

Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins

Copper(I)‐Catalyzed Cycloaddition of Organic Azides and 1‐Iodoalkynes

Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure

SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues

Copper-Catalyzed Synthesis of N-Sulfonyl-1,2,3-triazoles: Controlling Selectivity

Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates

Efficient Synthesis of 2-Substituted-1,2,3-triazoles

Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective "Ligation" of Azides and Terminal Alkynes

Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides

Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

Bioconjugation by Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans

A Sulfilimine Bond Identified in Collagen IV

Mechanistic Studies on the Cu-Catalyzed Three-Component Reactions of Sulfonyl Azides, 1-Alkynes and Amines, Alcohols, or Water: Dichotomy via a Common Pathway

Iterative In Situ Click Chemistry Creates Antibody-like Protein-Capture Agents

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