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Dynamin-related protein 1 as a therapeutic target in cardiac arrest

Journal of molecular medicine (Berlin, Germany), 2015-03, Vol.93 (3), p.243-252

Sharp, Willard W.

2015

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Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

The FASEB journal, 2014-01, Vol.28 (1), p.316-326

2014

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Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

Oncotarget, 2017-05, Vol.8 (21), p.34082-34098

2017

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Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function

Journal of molecular medicine (Berlin, Germany), 2015-03, Vol.93 (3), p.225-228

2015

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Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest

PloS one, 2017-09, Vol.12 (9), p.e0185046-e0185046

2017

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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications

Circulation (New York, N.Y.), 2020-07, Vol.142 (2), p.101-104

2020

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HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

eLife, 2022-07, Vol.11

2022

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Role of Dynamin-Related Protein 1 (Drp1)-Mediated Mitochondrial Fission in Oxygen Sensing and Constriction of the Ductus Arteriosus

Circulation research, 2013-03, Vol.112 (5), p.802-815

2013

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EM:RAP Commentaries in the Annals of Emergency Medicine : Peer Review and Financial Disclosure Needed

Annals of emergency medicine, 2015-07, Vol.66 (1), p.90-91

Sharp, Willard W., MD, PhD

2015

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Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants

American journal of physiology. Heart and circulatory physiology, 2010-06, Vol.298 (6), p.H2164-H2173

2010

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Community Response Programs: The Real Question Is “Are They Scalable?”

Annals of emergency medicine, 2023-07, Vol.82 (1), p.118-119

2023

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Emergency Department-initiated High-flow Nasal Cannula for COVID-19 Respiratory Distress

The western journal of emergency medicine, 2021-07, Vol.22 (4), p.979-987

2021

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Hands free pulse checks: The future of CPR

Resuscitation, 2024-02, Vol.195, p.110121-110121, Article 110121

2024

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The utility of computed tomography to evaluate thoracic complications after cardiopulmonary resuscitation

Resuscitation plus, 2020-09, Vol.3, p.100017-100017, Article 100017

2020

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Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension

Journal of molecular medicine (Berlin, Germany), 2017-04, Vol.95 (4), p.381-393

2017

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Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model

Critical care medicine, 2015-02, Vol.43 (2), p.e38-e47

2015

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Grape seed proanthocyanidins protect cardiomyocytes from ischemia and reperfusion injury via Akt-NOS signaling

Journal of cellular biochemistry, 2009-07, Vol.107 (4), p.697-705

2009

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Intermittent Hypoxia (IH) Impairs Hippocampal Oxygen Consumption and Neurophysiological Responses to Metabolic Challenge

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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PGC1α-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2013-04, Vol.187 (8), p.865-878

2013

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Dynamin‐related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury

The FASEB journal, 2024-01, Vol.38 (1), p.e23379-n/a

2024

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Emergency medicine faculty serving on standing NIH and AHRQ study sections from 2019 to 2020

Academic emergency medicine, 2022-01, Vol.29 (1), p.118-122

2022

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SAEM Response to the National Institutes of Health request for information: Future directions in violence against women research

Academic emergency medicine, 2023-11, Vol.30 (11), p.1161-1167

2023

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ACEP–SAEM response to the National Institutes of Health (NIH) proposal to simplify the review framework for research project grant applications

Academic emergency medicine, 2023-09, Vol.30 (9), p.963-964

2023

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Cost-utility of extracorporeal cardiopulmonary resuscitation in patients with cardiac arrest

Resuscitation, 2019-03, Vol.136, p.126-130

2019

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Microglial Activation and Neurological Outcomes in a Murine Model of Cardiac Arrest

Neurocritical care, 2022-02, Vol.36 (1), p.61-70

2022

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Dynamin-related protein 1 as a therapeutic target in cardiac arrest

Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function

Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest

Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications

HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

Role of Dynamin-Related Protein 1 (Drp1)-Mediated Mitochondrial Fission in Oxygen Sensing and Constriction of the Ductus Arteriosus

EM:RAP Commentaries in the Annals of Emergency Medicine : Peer Review and Financial Disclosure Needed

Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants

Community Response Programs: The Real Question Is “Are They Scalable?”

Emergency Department-initiated High-flow Nasal Cannula for COVID-19 Respiratory Distress

Hands free pulse checks: The future of CPR

The utility of computed tomography to evaluate thoracic complications after cardiopulmonary resuscitation

Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension

Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model

Grape seed proanthocyanidins protect cardiomyocytes from ischemia and reperfusion injury via Akt-NOS signaling

Intermittent Hypoxia (IH) Impairs Hippocampal Oxygen Consumption and Neurophysiological Responses to Metabolic Challenge

PGC1α-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension

Dynamin‐related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury

Emergency medicine faculty serving on standing NIH and AHRQ study sections from 2019 to 2020

SAEM Response to the National Institutes of Health request for information: Future directions in violence against women research

ACEP–SAEM response to the National Institutes of Health (NIH) proposal to simplify the review framework for research project grant applications

Cost-utility of extracorporeal cardiopulmonary resuscitation in patients with cardiac arrest

Microglial Activation and Neurological Outcomes in a Murine Model of Cardiac Arrest

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