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The P-glycoprotein efflux pump: how does it transport drugs?

The Journal of membrane biology, 1997-12, Vol.160 (3), p.161-175

Sharom, F J

1997

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Phospholipid Flippase Activity of the Reconstituted P-Glycoprotein Multidrug Transporter

Biochemistry (Easton), 2001-06, Vol.40 (23), p.6937-6947

2001

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Intrinsic Fluorescence of the P-glycoprotein Multidrug Transporter: Sensitivity of Tryptophan Residues to Binding of Drugs and Nucleotides

Biochemistry (Easton), 2000-12, Vol.39 (48), p.14927-14938

2000

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FRET Analysis Indicates That the Two ATPase Active Sites of the P-Glycoprotein Multidrug Transporter Are Closely Associated

Biochemistry (Easton), 2001-02, Vol.40 (5), p.1413-1422

2001

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Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

Biochemical journal, 1995-06, Vol.308 ( Pt 2) (2), p.381-390

1995

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Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein

The Journal of biological chemistry, 1993-11, Vol.268 (32), p.24197-24202

1993

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Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells

Biochemical pharmacology, 1999-08, Vol.58 (4), p.571-586

1999

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β‐Amyloid efflux mediated by p‐glycoprotein

Journal of neurochemistry, 2001-02, Vol.76 (4), p.1121-1128

2001

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MDR1 causes resistance to the antitumour drug miltefosine

British journal of cancer, 2001-05, Vol.84 (10), p.1405-1411

2001

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The Membrane Lipid Environment Modulates Drug Interactions with the P-Glycoprotein Multidrug Transporter

Biochemistry (Easton), 1999-05, Vol.38 (21), p.6887-6896

1999

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The P-glycoprotein multidrug transporter: interactions with membrane lipids, and their modulation of activity

Biochemical Society transactions, 1997-08, Vol.25 (3), p.1088-1096

Sharom, F J

1997

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The effects of lipids and detergents on ATPase-active P-glycoprotein

Biochimica et biophysica acta, 1993-02, Vol.1146 (1), p.65-72

1993

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Developmentally regulated changes in the glycoproteins of the equine embryonic capsule

Journal of reproduction & fertility, 1993-11, Vol.99 (2), p.653-664

1993

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Site-Directed Fluorescence Labeling of P-Glycoprotein on Cysteine Residues in the Nucleotide Binding Domains

Biochemistry (Easton), 1996-09, Vol.35 (36), p.11865-11873

1996

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Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells

Biochimica et biophysica acta, 1992-08, Vol.1109 (2), p.161-171

1992

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P‐Glycoprotein is localized in intermediate‐density membrane microdomains distinct from classical lipid rafts and caveolar domains

The FEBS journal, 2005-10, Vol.272 (19), p.4924-4937

2005

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Stoichiometry and Affinity of Nucleotide Binding to P-Glycoprotein during the Catalytic Cycle

Biochemistry (Easton), 2003-02, Vol.42 (4), p.1170-1177

2003

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Mucin-like glycoproteins in the equine embryonic capsule

Molecular reproduction and development, 1993-03, Vol.34 (3), p.255-265

1993

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Interaction of multidrug-resistant Chinese hamster ovary cells with amphiphiles

British journal of cancer, 1993-08, Vol.68 (2), p.342-351

1993

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Poster — Thur Eve — 38: The Effect of Ionizing Radiation on Giant Unilamellar Vesicles of “Lipid Raft” Mixtures Examined by Confocal Fluorescence Microscopy

Medical Physics, 2010-07, Vol.37 (7), p.3894-3894

2010

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Immunosuppression by YAC-1 Lymphoma: Role of Shed Gangliosides

Cellular immunology, 1996-10, Vol.173 (1), p.22-32

1996

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Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies

BBA - Biomembranes, 1999-12, Vol.1461 (2), p.327-345

1999

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Gangliosides inhibit T-lymphocyte proliferation by preventing the interaction of interleukin-2 with its cell surface receptors

Immunology, 1993-05, Vol.79 (1), p.10-17

1993

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Exploring the structure and function of the P-glycoprotein multidrug transporter using fluorescence spectroscopic tools

Seminars in cell & developmental biology, 2001-06, Vol.12 (3), p.257-265

2001

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Biochemical changes in the equine capsule following prostaglandin-induced pregnancy failure

Molecular reproduction and development, 1997-03, Vol.46 (3), p.286-295

1997

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The P-glycoprotein efflux pump: how does it transport drugs?

Phospholipid Flippase Activity of the Reconstituted P-Glycoprotein Multidrug Transporter

Intrinsic Fluorescence of the P-glycoprotein Multidrug Transporter: Sensitivity of Tryptophan Residues to Binding of Drugs and Nucleotides

FRET Analysis Indicates That the Two ATPase Active Sites of the P-Glycoprotein Multidrug Transporter Are Closely Associated

Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein

Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells

β‐Amyloid efflux mediated by p‐glycoprotein

MDR1 causes resistance to the antitumour drug miltefosine

The Membrane Lipid Environment Modulates Drug Interactions with the P-Glycoprotein Multidrug Transporter

The P-glycoprotein multidrug transporter: interactions with membrane lipids, and their modulation of activity

The effects of lipids and detergents on ATPase-active P-glycoprotein

Developmentally regulated changes in the glycoproteins of the equine embryonic capsule

Site-Directed Fluorescence Labeling of P-Glycoprotein on Cysteine Residues in the Nucleotide Binding Domains

Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells

P‐Glycoprotein is localized in intermediate‐density membrane microdomains distinct from classical lipid rafts and caveolar domains

Stoichiometry and Affinity of Nucleotide Binding to P-Glycoprotein during the Catalytic Cycle

Mucin-like glycoproteins in the equine embryonic capsule

Interaction of multidrug-resistant Chinese hamster ovary cells with amphiphiles

Poster — Thur Eve — 38: The Effect of Ionizing Radiation on Giant Unilamellar Vesicles of “Lipid Raft” Mixtures Examined by Confocal Fluorescence Microscopy

Immunosuppression by YAC-1 Lymphoma: Role of Shed Gangliosides

Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies

Gangliosides inhibit T-lymphocyte proliferation by preventing the interaction of interleukin-2 with its cell surface receptors

Exploring the structure and function of the P-glycoprotein multidrug transporter using fluorescence spectroscopic tools

Biochemical changes in the equine capsule following prostaglandin-induced pregnancy failure

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