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Investigating Novel Resistance Mechanisms to Third-Generation EGFR Tyrosine Kinase Inhibitor Osimertinib in Non-Small Cell Lung Cancer Patients

Clinical cancer research, 2018-07, Vol.24 (13), p.3097-3107

2018

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High prevalence of KRAS/BRAF somatic mutations in brain and spinal cord arteriovenous malformations

Brain (London, England : 1878), 2019-01, Vol.142 (1), p.23-34

2019

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Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types

Scientific reports, 2017-04, Vol.7 (1), p.583-583, Article 583

2017

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Novel Mutations on EGFR Leu792 Potentially Correlate to Acquired Resistance to Osimertinib in Advanced NSCLC

Journal of thoracic oncology, 2017-06, Vol.12 (6), p.e65-e68

2017

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Quantitative characterization of tumor cell-free DNA shortening

BMC genomics, 2020-07, Vol.21 (1), p.473-473, Article 473

2020

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Liquid biopsies to track trastuzumab resistance in metastatic HER2-positive gastric cancer

Gut, 2019-07, Vol.68 (7), p.1152-1161

2019

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Variability of EGFR exon 20 insertions in 24 468 Chinese lung cancer patients and their divergent responses to EGFR inhibitors

Molecular oncology, 2020-08, Vol.14 (8), p.1695-1704

2020

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Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

Nature cell biology, 2014-09, Vol.16 (9), p.889-901

2014

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Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancer

Theranostics, 2019-01, Vol.9 (19), p.5532-5541

2019

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Clinical outcomes of EGFR kinase domain duplication to targeted therapies in NSCLC

International journal of cancer, 2019-06, Vol.144 (11), p.2677-2682

2019

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Correlation of plasma exosomal microRNAs with the efficacy of immunotherapy in EGFR / ALK wild-type advanced non-small cell lung cancer

Journal for immunotherapy of cancer, 2020-01, Vol.8 (1), p.e000376

2020

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Clinical and molecular features of acute promyelocytic leukemia with variant retinoid acid receptor fusions

Haematologica (Roma), 2019-05, Vol.104 (5), p.e195-e199

2019

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Cell-Free DNA Provides a Good Representation of the Tumor Genome Despite Its Biased Fragmentation Patterns

PloS one, 2017-01, Vol.12 (1), p.e0169231-e0169231

2017

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Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of External Ventricular and Lumbar Drainage-Associated Ventriculitis and Meningitis

Frontiers in microbiology, 2020-12, Vol.11, p.596175-596175

2020

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JAK2 variations and functions in lung adenocarcinoma

Tumor biology, 2017-06, Vol.39 (6), p.1010428317711140-1010428317711140

2017

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SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients

BMC cancer, 2018-04, Vol.18 (1), p.479-7, Article 479

2018

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EML4-ALK, a potential therapeutic target that responds to alectinib in ovarian cancer

Japanese journal of clinical oncology, 2020-12, Vol.50 (12), p.1470-1474

2020

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Targeted next generation sequencing identified clinically actionable mutations in patients with esophageal sarcomatoid carcinoma

BMC cancer, 2018-03, Vol.18 (1), p.251-251, Article 251

2018

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Molecular genetic characterization reveals linear tumor evolution in a pulmonary sarcomatoid carcinomas patient with a novel PHF20-NTRK1 fusion: a case report

BMC cancer, 2019-06, Vol.19 (1), p.592-592, Article 592

2019

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YAP1 amplification as a prognostic factor of definitive chemoradiotherapy in nonsurgical esophageal squamous cell carcinoma

Cancer medicine (Malden, MA), 2020-03, Vol.9 (5), p.1628-1637

2020

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Short-Term Responders of Non–Small Cell Lung Cancer Patients to EGFR Tyrosine Kinase Inhibitors Display High Prevalence of TP53 Mutations and Primary Resistance Mechanisms

Translational oncology, 2018-12, Vol.11 (6), p.1364-1369

2018

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Unique Genomic Alterations of Cerebrospinal Fluid Cell-Free DNA Are Critical for Targeted Therapy of Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Frontiers in oncology, 2021-10, Vol.11, p.701171-701171

2021

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Monitoring treatment efficacy and resistance in breast cancer patients via circulating tumor DNA genomic profiling

Molecular genetics & genomic medicine, 2020-02, Vol.8 (2), p.e1079-n/a

2020

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Genomic dissection of gastrointestinal and lung neuroendocrine neoplasm

Chinese journal of cancer research, 2019-12, Vol.31 (6), p.918-929

2019

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Genetic aberrations in Chinese pancreatic cancer patients and their association with anatomic location and disease outcomes

Cancer medicine (Malden, MA), 2021-02, Vol.10 (3), p.933-943

2021

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Investigating Novel Resistance Mechanisms to Third-Generation EGFR Tyrosine Kinase Inhibitor Osimertinib in Non-Small Cell Lung Cancer Patients

High prevalence of KRAS/BRAF somatic mutations in brain and spinal cord arteriovenous malformations

Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types

Novel Mutations on EGFR Leu792 Potentially Correlate to Acquired Resistance to Osimertinib in Advanced NSCLC

Quantitative characterization of tumor cell-free DNA shortening

Liquid biopsies to track trastuzumab resistance in metastatic HER2-positive gastric cancer

Variability of EGFR exon 20 insertions in 24 468 Chinese lung cancer patients and their divergent responses to EGFR inhibitors

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancer

Clinical outcomes of EGFR kinase domain duplication to targeted therapies in NSCLC

Correlation of plasma exosomal microRNAs with the efficacy of immunotherapy in EGFR / ALK wild-type advanced non-small cell lung cancer

Clinical and molecular features of acute promyelocytic leukemia with variant retinoid acid receptor fusions

Cell-Free DNA Provides a Good Representation of the Tumor Genome Despite Its Biased Fragmentation Patterns

Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of External Ventricular and Lumbar Drainage-Associated Ventriculitis and Meningitis

JAK2 variations and functions in lung adenocarcinoma

SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients

EML4-ALK, a potential therapeutic target that responds to alectinib in ovarian cancer

Targeted next generation sequencing identified clinically actionable mutations in patients with esophageal sarcomatoid carcinoma

Molecular genetic characterization reveals linear tumor evolution in a pulmonary sarcomatoid carcinomas patient with a novel PHF20-NTRK1 fusion: a case report

YAP1 amplification as a prognostic factor of definitive chemoradiotherapy in nonsurgical esophageal squamous cell carcinoma

Short-Term Responders of Non–Small Cell Lung Cancer Patients to EGFR Tyrosine Kinase Inhibitors Display High Prevalence of TP53 Mutations and Primary Resistance Mechanisms

Unique Genomic Alterations of Cerebrospinal Fluid Cell-Free DNA Are Critical for Targeted Therapy of Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Monitoring treatment efficacy and resistance in breast cancer patients via circulating tumor DNA genomic profiling

Genomic dissection of gastrointestinal and lung neuroendocrine neoplasm

Genetic aberrations in Chinese pancreatic cancer patients and their association with anatomic location and disease outcomes

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