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The anti‐hepatic fibrosis effects of dihydrotanshinone I are mediated by disrupting the yes‐associated protein and transcriptional enhancer factor D2 complex and stimulating autophagy

British journal of pharmacology, 2017-05, Vol.174 (10), p.1147-1160

2017

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Costunolide represses hepatic fibrosis through WW domain‐containing protein 2‐mediated Notch3 degradation

British journal of pharmacology, 2020-01, Vol.177 (2), p.372-387

2020

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G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3β and stabilizing β-catenin

Acta pharmacologica Sinica, 2021-11, Vol.42 (11), p.1900-1912

2021

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GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin‐mediated cytotoxicity to colon carcinoma HCT116 cells

Cancer science, 2012-10, Vol.103 (10), p.1848-1856

2012

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Cardiac glycosides induce autophagy in human non-small cell lung cancer cells through regulation of dual signaling pathways

The international journal of biochemistry & cell biology, 2012-11, Vol.44 (11), p.1813-1824

2012

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Protective effect of gastrodin on bile duct ligation-induced hepatic fibrosis in rats

Food and chemical toxicology, 2015-12, Vol.86, p.202-207

2015

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The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway

Acta pharmacologica Sinica, 2015-04, Vol.36 (4), p.473-482

2015

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A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters

Acta pharmacologica Sinica, 2019-07, Vol.40 (7), p.895-907

2019

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EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62-mediated lysosomal degradation of c-Myc

Acta pharmacologica Sinica, 2018-08, Vol.39 (8), p.1347-1358

2018

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A novel biphenyl compound IMB-S7 ameliorates hepatic fibrosis in BDL rats by suppressing Sp1-mediated integrin αv expression

Acta pharmacologica Sinica, 2020-05, Vol.41 (5), p.661-669

2020

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Small Molecular Compounds Inhibit HIV-1 Replication through Specifically Stabilizing APOBEC3G

The Journal of biological chemistry, 2010-05, Vol.285 (22), p.16546-16552

2010

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Enediyne anticancer antibiotic lidamycin: chemistry, biology and pharmacology

Anti-cancer agents in medicinal chemistry, 2008-02, Vol.8 (2), p.123-131

2008

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D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acid secretion and attenuating oxidative stress

Acta pharmacologica Sinica, 2018-02, Vol.39 (2), p.213-221

2018

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The novel quinolizidine derivate IMB-HDC inhibits STAT5a phosphorylation at 694 and 780 and promotes DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation

Acta pharmacologica Sinica, 2020-05, Vol.41 (5), p.686-697

2020

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SPHK1 (sphingosine kinase 1) induces epithelial-mesenchymal transition by promoting the autophagy-linked lysosomal degradation of CDH1/E-cadherin in hepatoma cells

Autophagy, 2017-05, Vol.13 (5), p.900-913

2017

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Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanism

BMC ophthalmology, 2020-03, Vol.20 (1), p.92-92, Article 92

2020

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Lidamycin decreases CD133 expression in hepatocellular carcinoma via the Notch signaling pathway

Oncology letters, 2017-12, Vol.14 (6), p.7889-7895

2017

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Lidamycin inhibits tumor initiating cells of hepatocellular carcinoma Huh7 through GSK3β/β-catenin pathway

Molecular carcinogenesis, 2015-01, Vol.54 (1), p.1-8

2015

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MR-1 Modulates Proliferation and Migration of Human Hepatoma HepG2 Cells through Myosin Light Chains-2 (MLC2)/Focal Adhesion Kinase (FAK)/Akt Signaling Pathway

The Journal of biological chemistry, 2008-12, Vol.283 (51), p.35598-35605

2008

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Heat Stress Cognate 70 Host Protein as a Potential Drug Target against Drug Resistance in Hepatitis B Virus

Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.2070-2077

2010

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Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

The EMBO journal, 1999-03, Vol.18 (5), p.1397-1406

1999

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Advances in understanding the regulatory mechanism of cholesterol 7α-hydroxylase

Biochemical pharmacology, 2019-06, Vol.164, p.152-164

2019

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Recent progression in the utilization of autophagy-regulating nature compound as anti-liver fibrosis agents

Journal of Asian Natural Products Research, 2017-02, Vol.19 (2), p.109-113

2017

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Pharmacology and Therapeutic Applications of Enediyne Antitumor Antibiotics

Current molecular pharmacology, 2008-01, Vol.1 (1), p.50-60

Shao, Rong-Guang

2008

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Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis

Cancer biology & therapy, 2009-08, Vol.8 (16), p.1559-1566

2009

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The anti‐hepatic fibrosis effects of dihydrotanshinone I are mediated by disrupting the yes‐associated protein and transcriptional enhancer factor D2 complex and stimulating autophagy

Costunolide represses hepatic fibrosis through WW domain‐containing protein 2‐mediated Notch3 degradation

G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3β and stabilizing β-catenin

GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin‐mediated cytotoxicity to colon carcinoma HCT116 cells

Cardiac glycosides induce autophagy in human non-small cell lung cancer cells through regulation of dual signaling pathways

Protective effect of gastrodin on bile duct ligation-induced hepatic fibrosis in rats

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway

A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters

EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62-mediated lysosomal degradation of c-Myc

A novel biphenyl compound IMB-S7 ameliorates hepatic fibrosis in BDL rats by suppressing Sp1-mediated integrin αv expression

Small Molecular Compounds Inhibit HIV-1 Replication through Specifically Stabilizing APOBEC3G

Enediyne anticancer antibiotic lidamycin: chemistry, biology and pharmacology

D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acid secretion and attenuating oxidative stress

The novel quinolizidine derivate IMB-HDC inhibits STAT5a phosphorylation at 694 and 780 and promotes DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation

SPHK1 (sphingosine kinase 1) induces epithelial-mesenchymal transition by promoting the autophagy-linked lysosomal degradation of CDH1/E-cadherin in hepatoma cells

Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanism

Lidamycin decreases CD133 expression in hepatocellular carcinoma via the Notch signaling pathway

Lidamycin inhibits tumor initiating cells of hepatocellular carcinoma Huh7 through GSK3β/β-catenin pathway

MR-1 Modulates Proliferation and Migration of Human Hepatoma HepG2 Cells through Myosin Light Chains-2 (MLC2)/Focal Adhesion Kinase (FAK)/Akt Signaling Pathway

Heat Stress Cognate 70 Host Protein as a Potential Drug Target against Drug Resistance in Hepatitis B Virus

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

Advances in understanding the regulatory mechanism of cholesterol 7α-hydroxylase

Recent progression in the utilization of autophagy-regulating nature compound as anti-liver fibrosis agents

Pharmacology and Therapeutic Applications of Enediyne Antitumor Antibiotics

Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis

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