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Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

Nature chemical biology, 2012-02, Vol.8 (4), p.393-399

2012

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Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates

Nature chemical biology, 2022-03, Vol.18 (3), p.332-341

2022

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Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Nature communications, 2023-04, Vol.14 (1), p.2057-2057, Article 2057

2023

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Pharmacological Inhibition of O‑GlcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway

ACS chemical neuroscience, 2018-06, Vol.9 (6), p.1366-1379

2018

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A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors

Angewandte Chemie (International ed.), 2015-12, Vol.54 (51), p.15429-15433

International ed. in English, 2015

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Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS

Neuroscience letters, 2009-07, Vol.458 (2), p.70-74

2009

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Enhanced De Novo Neurogenesis and Dopaminergic Neurogenesis in the Substantia Nigra of 1‐Methyl‐4‐phyenyl‐1,2,3,6‐Tetrahydropyridine‐Induced Parkinson's Disease‐Like Mice

Stem cells (Dayton, Ohio), 2006-05, Vol.24 (5), p.1280-1287

2006

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Manganese superoxide dismutase protects mouse cortical neurons from chronic intermittent hypoxia-mediated oxidative damage

Neurobiology of disease, 2007-11, Vol.28 (2), p.206-215

2007

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The Emerging Link between O-GlcNAc and Alzheimer Disease

The Journal of biological chemistry, 2014-12, Vol.289 (50), p.34472-34481

2014

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Spatio-temporal variation and drivers of blue carbon sequestration in Hainan Island, China

Marine environmental research, 2024-05, Vol.197, p.106476-106476, Article 106476

2024

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PKDGA: A Partial Knowledge-based Domain Generation Algorithm for Botnets

IEEE transactions on information forensics and security, 2023-01, Vol.18, p.1-1

2023

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A Game-based Adversarial DGA Detection Scheme using Multi-level Incremental Random Forest

IEEE transactions on network science and engineering, 2024-01, Vol.11 (1), p.1-13

2024

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Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing

Angewandte Chemie International Edition, 2018-06, Vol.57 (26), p.7644-7648

International ed. in English, 2018

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Modeling nutrient flows from land to rivers and seas – A review and synthesis

Marine environmental research, 2023-04, Vol.186, p.105928-105928, Article 105928

2023

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Fluorescence-Quenched Substrates for Live Cell Imaging of Human Glucocerebrosidase Activity

Journal of the American Chemical Society, 2015-01, Vol.137 (3), p.1181-1189

2015

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Reduced protein O-glycosylation in the nervous system of the mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis

Neuroscience letters, 2012-05, Vol.516 (2), p.296-301

2012

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A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

Nature chemical biology, 2008-08, Vol.4 (8), p.483-490

2008

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Drainage and Orbitofrontal Reconstruction After Removal of a Giant Frontal Sinus Osteoma: A Case Report

Ear, nose, & throat journal, 2022-05, p.1455613221098786-1455613221098786

2022

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A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors

Angewandte Chemie, 2015-12, Vol.127 (51), p.15649-15653

2015

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Comparison of Er:YAG laser and ultrasonic in root canal disinfection under minimally invasive access cavity

Lasers in medical science, 2022-10, Vol.37 (8), p.3249-3258

2022

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A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells

Proceedings of the National Academy of Sciences - PNAS, 2022-07, Vol.119 (29), p.e2200553119-e2200553119

2022

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Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice

Molecular neurodegeneration, 2014-10, Vol.9 (1), p.42-42, Article 42

2014

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Selective Fluorogenic β‑Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates

ACS chemical biology, 2020-04, Vol.15 (4), p.824-829

2020

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Modulation of O‐GlcNAc levels as a disease modifying approach for Alzheimer disease (223.3)

The FASEB journal, 2014-04, Vol.28 (S1), p.n/a

2014

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Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing

Angewandte Chemie, 2018-06, Vol.130 (26), p.7770-7774

2018

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Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Pharmacological Inhibition of O‑GlcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway

A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors

Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS

Enhanced De Novo Neurogenesis and Dopaminergic Neurogenesis in the Substantia Nigra of 1‐Methyl‐4‐phyenyl‐1,2,3,6‐Tetrahydropyridine‐Induced Parkinson's Disease‐Like Mice

Manganese superoxide dismutase protects mouse cortical neurons from chronic intermittent hypoxia-mediated oxidative damage

The Emerging Link between O-GlcNAc and Alzheimer Disease

Spatio-temporal variation and drivers of blue carbon sequestration in Hainan Island, China

PKDGA: A Partial Knowledge-based Domain Generation Algorithm for Botnets

A Game-based Adversarial DGA Detection Scheme using Multi-level Incremental Random Forest

Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing

Modeling nutrient flows from land to rivers and seas – A review and synthesis

Fluorescence-Quenched Substrates for Live Cell Imaging of Human Glucocerebrosidase Activity

Reduced protein O-glycosylation in the nervous system of the mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

Drainage and Orbitofrontal Reconstruction After Removal of a Giant Frontal Sinus Osteoma: A Case Report

A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors

Comparison of Er:YAG laser and ultrasonic in root canal disinfection under minimally invasive access cavity

A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells

Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice

Selective Fluorogenic β‑Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates

Modulation of O‐GlcNAc levels as a disease modifying approach for Alzheimer disease (223.3)

Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing

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