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Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E–Deficient Mice

Circulation (New York, N.Y.), 2016-06, Vol.133 (23), p.2263-2278

2016

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Endothelial deficiency of insulin-like growth factor-1 receptor reduces endothelial barrier function and promotes atherosclerosis in Apoe -deficient mice

American journal of physiology. Heart and circulatory physiology, 2020-10, Vol.319 (4), p.H730-H743

2020

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Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of COL1a1 and COL1a2 mRNA

The Journal of biological chemistry, 2014-03, Vol.289 (11), p.7264-7274

2014

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IGF-1, oxidative stress and atheroprotection

Trends in endocrinology and metabolism, 2010-04, Vol.21 (4), p.245-254

2010

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IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice

Arteriosclerosis, thrombosis, and vascular biology, 2007-12, Vol.27 (12), p.2684

2007

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Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase

Atherosclerosis, 2015-02, Vol.238 (2), p.313-320

2015

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Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling

Molecular and Cellular Biology, 2008-01, Vol.28 (2), p.794-802

2008

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Aging, atherosclerosis, and IGF-1

The journals of gerontology. Series A, Biological sciences and medical sciences, 2012-06, Vol.67 (6), p.626-639

2012

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Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability

Arteriosclerosis, thrombosis, and vascular biology, 2010-10, Vol.30 (10), p.1916

2010

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Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice

American journal of physiology. Heart and circulatory physiology, 2011-05, Vol.300 (5), p.H1898-H1906

2011

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Combined Deficiency of Dystrophin and β1 Integrin in the Cardiac Myocyte Causes Myocardial Dysfunction, Fibrosis and Calcification

Circulation research, 2008-05, Vol.102 (9), p.1109-1117

2008

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SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2018-10, Vol.38 (10), p.2306

2018

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Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging

Frontiers of hormone research, 2014, Vol.43, p.107

2014

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Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

The American journal of pathology, 2001-03, Vol.158 (3), p.1079-1090

2001

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Modulation of integrins and integrin signaling molecules in the pressure-loaded murine ventricle

Histochemistry and cell biology, 2002-12, Vol.118 (6), p.431-439

2002

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Novel Effect of Oxidized Low-Density Lipoprotein: Cellular ATP Depletion via Downregulation of Glyceraldehyde-3-Phosphate Dehydrogenase

Circulation research, 2006-07, Vol.99 (2), p.191-200

2006

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Glucocorticoids Induce Angiotensin-Converting Enzyme Expression in Vascular Smooth Muscle

Hypertension (Dallas, Tex. 1979), 1995-03, Vol.25 (3), p.343-349

1995

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Beta(1) integrins participate in the hypertrophic response of rat ventricular myocytes

Circulation research, 1998-06, Vol.82 (11), p.1160

1998

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Bovine Angiotensin Converting Enzyme cDNA Cloning and Regulation: Increased Expression During Endothelial Cell Growth Arrest

Circulation research, 1992-06, Vol.70 (6), p.1274-1281

1992

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Macrophage Specific IGF‐1 Overexpression Decreases Atherosclerosis, CXCL12 Chemokine, And Increases Cholesterol Efflux In ApoE Deficient Mice

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.02489

2021

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Features of Stable Plaque Phenotype Are Increased by Macrophage Specific Insulin‐Like Growth Factor 1

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene

Molecular and Cellular Biology, 1990-08, Vol.10 (8), p.4294-4302

1990

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Macrophage Insulin‐Like Growth Factor 1 Downregulated Matrix Metalloproteinases and Promoted Features of a Stable Atherosclerotic Plaque

The FASEB journal, 2019-04, Vol.33 (S1), p.522.6-522.6

2019

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Macrophage Insulin‐Like Growth Factor I (IGF1) Upregulates Atherosclerotic Plaque Collagen and Suppresses Atherosclerosis by Reducing Matrix Metalloproteinases

The FASEB journal, 2018-04, Vol.32 (S1), p.572.7-572.7

2018

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Genomic DNA 5′ to the mouse and human angiotensin-converting enzyme genes contains two distinct regions of conserved sequence

Biochemical and biophysical research communications, 1990-03, Vol.167 (3), p.1128-1133

1990

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Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E–Deficient Mice

Endothelial deficiency of insulin-like growth factor-1 receptor reduces endothelial barrier function and promotes atherosclerosis in Apoe -deficient mice

Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of COL1a1 and COL1a2 mRNA

IGF-1, oxidative stress and atheroprotection

IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice

Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase

Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling

Aging, atherosclerosis, and IGF-1

Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability

Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice

Combined Deficiency of Dystrophin and β1 Integrin in the Cardiac Myocyte Causes Myocardial Dysfunction, Fibrosis and Calcification

SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis

Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging

Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

Modulation of integrins and integrin signaling molecules in the pressure-loaded murine ventricle

Novel Effect of Oxidized Low-Density Lipoprotein: Cellular ATP Depletion via Downregulation of Glyceraldehyde-3-Phosphate Dehydrogenase

Glucocorticoids Induce Angiotensin-Converting Enzyme Expression in Vascular Smooth Muscle

Beta(1) integrins participate in the hypertrophic response of rat ventricular myocytes

Bovine Angiotensin Converting Enzyme cDNA Cloning and Regulation: Increased Expression During Endothelial Cell Growth Arrest

Macrophage Specific IGF‐1 Overexpression Decreases Atherosclerosis, CXCL12 Chemokine, And Increases Cholesterol Efflux In ApoE Deficient Mice

Features of Stable Plaque Phenotype Are Increased by Macrophage Specific Insulin‐Like Growth Factor 1

Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene

Macrophage Insulin‐Like Growth Factor 1 Downregulated Matrix Metalloproteinases and Promoted Features of a Stable Atherosclerotic Plaque

Macrophage Insulin‐Like Growth Factor I (IGF1) Upregulates Atherosclerotic Plaque Collagen and Suppresses Atherosclerosis by Reducing Matrix Metalloproteinases

Genomic DNA 5′ to the mouse and human angiotensin-converting enzyme genes contains two distinct regions of conserved sequence

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