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The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

Molecular cell, 2015-11, Vol.60 (3), p.351-361

2015

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Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic

NPJ precision oncology, 2017-06, Vol.1 (1), p.1-19, Article 19

2017

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The thioredoxin system in breast cancer cell invasion and migration

Redox biology, 2016-08, Vol.8 (C), p.68-78

2016

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Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

Scientific reports, 2018-09, Vol.8 (1), p.13759-14, Article 13759

2018

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The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2

Cell reports (Cambridge), 2017-01, Vol.18 (3), p.611-623

2017

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Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target

Journal of experimental & clinical cancer research, 2021-08, Vol.40 (1), p.251-251, Article 251

2021

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APE1/Ref‐1 knockdown in pancreatic ductal adenocarcinoma – characterizing gene expression changes and identifying novel pathways using single‐cell RNA sequencing

Molecular oncology, 2017-12, Vol.11 (12), p.1711-1732

2017

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Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression

Molecular oncology, 2024-01, Vol.18 (1), p.113-135

2024

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Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells

Biochemical and biophysical research communications, 2012-03, Vol.419 (2), p.350-355

2012

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[Letter to the editor] The selenium content of cell culture serum influences redox-regulated gene expression

BioTechniques, 2011-05, Vol.50 (4), p.295-301

2011

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Factors associated with persistent opioid use after an upper extremity fracture

Bone & joint open, 2021-02, Vol.2 (2), p.119-124

2021

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LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data

Nucleic acids research, 2019-10, Vol.47 (18), p.e111-e111

2019

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Abstract PO025: Ref-1 redox function identified as mitochondrial metabolic regulator in pancreatic cancer cells but not in CAFs

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (5_Supplement), p.PO025-PO025

2021

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Abstract 2941: APE1/Ref-1 redox signaling regulates HIF1a-mediated CA9 expression in hypoxic pancreatic cancer cells: Combination treatment in patient-derived pancreatic tumor models

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2941-2941

2018

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Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization

The Journal of pharmacology and experimental therapeutics, 2018-10, Vol.367 (1), p.108-118

2018

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Abstract 4802: Combination therapy in PDAC involving blockade of the APE1/Ref-1 signaling pathway: An investigation into drug synthetic lethality and anti-neuropathy therapeutic approach

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4802-4802

2018

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Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2651-2665

2019

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Assessment of the outcome of fracture intertrochanteric femur treated by trochanteric fixation nail in the elderly population

International Journal of Research in Orthopaedics, 2020-12, Vol.7 (1), p.125

2020

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Assessment of the outcome of fracture proximal humerus transdeltoid versus deltopectoral approach with PHILOS

International Journal of Research in Orthopaedics, 2020-12, Vol.7 (1), p.25

2020

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Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

British journal of cancer, 2021-04, Vol.124 (9), p.1566-1580

2021

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Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

British journal of cancer, 2022-10, Vol.127 (7), p.1378-1379

2022

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Combined inhibition of Ref‐1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co‐culture models

Journal of cellular and molecular medicine, 2021-01, Vol.25 (2), p.784-800

2021

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Abstract C017: Signaling through Ref-1 and STAT3 in soft tissue sarcoma (MPNST) and the effects of perturbing this pathway on tumor cell survival and gene expression

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.C017-C017

2019

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Abstract A023: Preclinical development of PKMYT1 and WEE1 inhibitor combinations

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.A023-A023

2023

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Abstract 4740: Targeting Ref-1/APE1 pathway inhibition in pancreatic cancer using APX3330 for clinical trials

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4740-4740

2016

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The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic

The thioredoxin system in breast cancer cell invasion and migration

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2

Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target

APE1/Ref‐1 knockdown in pancreatic ductal adenocarcinoma – characterizing gene expression changes and identifying novel pathways using single‐cell RNA sequencing

Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression

Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells

[Letter to the editor] The selenium content of cell culture serum influences redox-regulated gene expression

Factors associated with persistent opioid use after an upper extremity fracture

LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data

Abstract PO025: Ref-1 redox function identified as mitochondrial metabolic regulator in pancreatic cancer cells but not in CAFs

Abstract 2941: APE1/Ref-1 redox signaling regulates HIF1a-mediated CA9 expression in hypoxic pancreatic cancer cells: Combination treatment in patient-derived pancreatic tumor models

Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization

Abstract 4802: Combination therapy in PDAC involving blockade of the APE1/Ref-1 signaling pathway: An investigation into drug synthetic lethality and anti-neuropathy therapeutic approach

Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer

Assessment of the outcome of fracture intertrochanteric femur treated by trochanteric fixation nail in the elderly population

Assessment of the outcome of fracture proximal humerus transdeltoid versus deltopectoral approach with PHILOS

Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

Combined inhibition of Ref‐1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co‐culture models

Abstract C017: Signaling through Ref-1 and STAT3 in soft tissue sarcoma (MPNST) and the effects of perturbing this pathway on tumor cell survival and gene expression

Abstract A023: Preclinical development of PKMYT1 and WEE1 inhibitor combinations

Abstract 4740: Targeting Ref-1/APE1 pathway inhibition in pancreatic cancer using APX3330 for clinical trials

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