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Drug-Membrane Interactions: Analysis, Drug Distribution, Modeling

1, 2002

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Structure−Activity Relationship Studies on Benzofuran Analogs of Propafenone-Type Modulators of Tumor Cell Multidrug Resistance

Journal of medicinal chemistry, 1996-11, Vol.39 (24), p.4767-4774

1996

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Membrane interactions of some catamphiphilic drugs and relation to their multidrug-resistance-reversing ability

Journal of cancer research and clinical oncology, 1996, Vol.122 (1), p.27-40

1996

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Partial resistance of E. coli mutants against 2,4-diamino-5-benzylpyrimidines by interactions with bacterial membrane lipopolysaccharides. Derivation of quantitative structure–binding relationships

European journal of medicinal chemistry, 2000-06, Vol.35 (6), p.619-634

2000

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Drug Membrane Interaction and the Importance for Drug Transport, Distribution, Accumulation, Efficacy and Resistance

Archiv der Pharmazie (Weinheim), 1994, Vol.327 (10), p.601-610

1994

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Effect of Hydroxypropyl-β-cyclodextrin on the Antimicrobial Action of Preservatives

Journal of pharmacy and pharmacology, 1994-03, Vol.46 (3), p.186-191

1994

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A quantitative structure-activity relationship analysis of some 4-aminodiphenyl sulfone antibacterial agents using linear free energy and molecular modeling methods

Journal of medicinal chemistry, 1987-05, Vol.30 (5), p.900-906

1987

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Synthesis and Quantitative Structure-Activity Relationships of Anticonvulsant 2,3,6-Triaminopyridines

Journal of medicinal chemistry, 1994-09, Vol.37 (19), p.3016-3022

1994

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Penetration of rifampicin into the cerebrospinal fluid of adults with uninflamed meninges

Journal of antimicrobial chemotherapy, 1992-06, Vol.29 (6), p.719-724

1992

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Interaction of Prostaglandin E1 with α-Cyclodextrin in Aqueous Systems: Stability of the Inclusion Complex

Journal of pharmaceutical sciences, 1991-02, Vol.80 (2), p.153-156

1991

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Interactions between p-hydroxybenzoic acid esters and hydroxypropyl-β-cyclodextrin and their antimicrobial effect against Candida albicans

International journal of pharmaceutics, 1993-05, Vol.93 (1), p.201-208

1993

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Effect of cyclodextrin derivatives on indomethacin stability in aqueous solution

Pharmaceutical research, 1990-05, Vol.7 (5), p.484-490

1990

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A time Hierarchy-Based Model for Kinetics of Drug Disposition and Its Use in Quantitative Structure—Activity Relationships

Journal of pharmaceutical sciences, 1992-09, Vol.81 (9), p.849-857

1992

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Studies on the Inhibitory Effects of Analogues of Dapsone on Neutrophil Function In-vitro

Journal of pharmacy and pharmacology, 1997-01, Vol.49 (1), p.53-57

1997

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In Vitro and In Vivo Results of Brodimoprim and Analogues Alone and in Combination against E. coli and Mycobacteria

Journal of chemotherapy, 1993-12, Vol.5 (6), p.422-429

Seydel, J.K.

1993

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Application of bacterial growth kinetics to in vitro toxicity assessment of substituted phenols and anilines

Ecotoxicology and environmental safety, 1990-04, Vol.19 (2), p.228-241

1990

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Studies on the Toxicity of Analogues of Dapsone In-vitro Using Rat, Human and Heterologously Expressed Metabolizing Systems

Journal of pharmacy and pharmacology, 1996-09, Vol.48 (9), p.945-950

1996

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New Antifolate 4,4′-Diaminodiphenyl Sulfone Substituted 2,4-Diamino-5-benzylpyrimidines. Proof of Their Dual Mode of Action and Autosynergism

Archiv der Pharmazie (Weinheim), 1996, Vol.329 (3), p.161-168

1996

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Influence of membrane composition of various parasites on the inhibitory activity of a series of bipyridyl analogues

Chemotherapy (Basel), 1994-03, Vol.40 (2), p.124-135

1994

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Quantitative structure-toxicity relationships for ecotoxicologically relevant biotestsystems and chemicals

Chemosphere (Oxford), 1988, Vol.17 (8), p.1585-1602

1988

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New benzylpyrimidines: inhibition of DHFR from various species. QSAR, CoMFA and PC analysis

European journal of medicinal chemistry, 1995, Vol.30 (10), p.779-787

1995

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Quantitative structure-pharmacokinetic relationships and drug design

Pharmacology & therapeutics (Oxford), 1981, Vol.15 (2), p.131-182

1981

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Substituted 2-acylpyridine-alpha-(N)-hetarylhydrazones as inhibitors of ribonucleotide reductase activity and L1210 cell growth

Anticancer research, 1994-05, Vol.14 (3A), p.875

1994

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A kinetic description of the fate of chemicals in biosystems

Science of the total environment, 1991-12, Vol.109, p.357-375

1991

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Folate-Synthesizing Enzyme System as Target for Development of Inhibitors and Inhibitor Combinations against Candida albicansSynthesis and Biological Activity of New 2,4-Diaminopyrimidines and 4‘-Substituted 4-Aminodiphenyl Sulfones

Journal of medicinal chemistry, 2004-01, Vol.47 (1), p.240-253

2004

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Drug-Membrane Interactions: Analysis, Drug Distribution, Modeling

Structure−Activity Relationship Studies on Benzofuran Analogs of Propafenone-Type Modulators of Tumor Cell Multidrug Resistance

Membrane interactions of some catamphiphilic drugs and relation to their multidrug-resistance-reversing ability

Partial resistance of E. coli mutants against 2,4-diamino-5-benzylpyrimidines by interactions with bacterial membrane lipopolysaccharides. Derivation of quantitative structure–binding relationships

Drug Membrane Interaction and the Importance for Drug Transport, Distribution, Accumulation, Efficacy and Resistance

Effect of Hydroxypropyl-β-cyclodextrin on the Antimicrobial Action of Preservatives

A quantitative structure-activity relationship analysis of some 4-aminodiphenyl sulfone antibacterial agents using linear free energy and molecular modeling methods

Synthesis and Quantitative Structure-Activity Relationships of Anticonvulsant 2,3,6-Triaminopyridines

Penetration of rifampicin into the cerebrospinal fluid of adults with uninflamed meninges

Interaction of Prostaglandin E1 with α-Cyclodextrin in Aqueous Systems: Stability of the Inclusion Complex

Interactions between p-hydroxybenzoic acid esters and hydroxypropyl-β-cyclodextrin and their antimicrobial effect against Candida albicans

Effect of cyclodextrin derivatives on indomethacin stability in aqueous solution

A time Hierarchy-Based Model for Kinetics of Drug Disposition and Its Use in Quantitative Structure—Activity Relationships

Studies on the Inhibitory Effects of Analogues of Dapsone on Neutrophil Function In-vitro

In Vitro and In Vivo Results of Brodimoprim and Analogues Alone and in Combination against E. coli and Mycobacteria

Application of bacterial growth kinetics to in vitro toxicity assessment of substituted phenols and anilines

Studies on the Toxicity of Analogues of Dapsone In-vitro Using Rat, Human and Heterologously Expressed Metabolizing Systems

New Antifolate 4,4′-Diaminodiphenyl Sulfone Substituted 2,4-Diamino-5-benzylpyrimidines. Proof of Their Dual Mode of Action and Autosynergism

Influence of membrane composition of various parasites on the inhibitory activity of a series of bipyridyl analogues

Quantitative structure-toxicity relationships for ecotoxicologically relevant biotestsystems and chemicals

New benzylpyrimidines: inhibition of DHFR from various species. QSAR, CoMFA and PC analysis

Quantitative structure-pharmacokinetic relationships and drug design

Substituted 2-acylpyridine-alpha-(N)-hetarylhydrazones as inhibitors of ribonucleotide reductase activity and L1210 cell growth

A kinetic description of the fate of chemicals in biosystems

Folate-Synthesizing Enzyme System as Target for Development of Inhibitors and Inhibitor Combinations against Candida albicansSynthesis and Biological Activity of New 2,4-Diaminopyrimidines and 4‘-Substituted 4-Aminodiphenyl Sulfones

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