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Drug metabolism in hepatocyte sandwich cultures of rats and humans

Biochemical pharmacology, 1997-10, Vol.54 (7), p.761-772

1997

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Helicobacter pylori causes DNA damage in gastric epithelial cells

Carcinogenesis (New York), 2000-06, Vol.21 (6), p.1111-1115

2000

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Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat

Drug metabolism and disposition, 1992-09, Vol.20 (5), p.753

1992

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Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability

Drug metabolism and disposition, 1995-12, Vol.23 (12), p.1315

1995

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Cyclosporin metabolism in transplant patients

Pharmacology & therapeutics (Oxford), 1993, Vol.57 (2), p.291-345

1993

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Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

Drug metabolism and disposition, 1999-02, Vol.27 (2), p.173

1999

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Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray- mass spectrometry

Clinical chemistry (Baltimore, Md.), 1996-09, Vol.42 (9), p.1417-1425

1996

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Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber

British journal of pharmacology, 1996-04, Vol.117 (8), p.1730-1734

1996

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Helicobacter pylori augments the acid inhibitory effect of omeprazole on parietal cells and gastric H+/K+-ATPase

Gut, 2001-02, Vol.48 (2), p.157-162

2001

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Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients

Clinical chemistry (Baltimore, Md.), 1996-09, Vol.42 (9), p.1426-1432

1996

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Interaction of Helicobacter pylori and its fatty acids with parietal cells and gastric H+/K(+)-ATPase

Gut, 1994-09, Vol.35 (9), p.1176-1180

1994

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Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells

Journal of clinical microbiology, 2000-06, Vol.38 (6), p.2215-2218

2000

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Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin

Drug metabolism and disposition, 2000-11, Vol.28 (11), p.1369

2000

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Structural elucidation by electrospray mass spectrometry: an approach to the in vitro metabolism of the macrolide immunosuppressant SDZ RAD

Journal of the American Society for Mass Spectrometry, 1998-12, Vol.9 (12), p.1267-1274

1998

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Structural identification of three metabolites and a degradation product of the macrolide immunosuppressant sirolimus (rapamycin) by electrospray-MS/MS after incubation with human liver microsomes

Drug metabolism and disposition, 1996-11, Vol.24 (11), p.1272

1996

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3-D Coculture of Hepatic Sinusoidal Cells with Primary Hepatocytes—Design of an Organotypical Model

Experimental cell research, 1996-07, Vol.226 (1), p.223-233

1996

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Helicobacter pylori reduces intracellular glutathione in gastric epithelial cells

Digestive diseases and sciences, 2000-09, Vol.45 (9), p.1769-1773

2000

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Automated simultaneous quantification of the immunosuppressants 40-O-(2-hydroxyethyl)rapamycin and cyclosporine in blood with electrospray-mass spectrometric detection

Clinical chemistry (Baltimore, Md.), 1998-06, Vol.44 (6), p.1275-1282

1998

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Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients

British journal of clinical pharmacology, 1996-06, Vol.41 (6), p.551-556

1996

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Automated, fast and sensitive quantification of drugs in blood by liquid chromatography–mass spectrometry with on-line extraction: immunosuppressants

Journal of chromatography. B, Biomedical sciences and applications, 2000-10, Vol.748 (1), p.41-53

2000

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Pharmacokinetics, dosing principles, and blood level monitoring of FK506

Transplantation proceedings, 1994-12, Vol.26 (6), p.3267-3269

SEWING, K.-F

1994

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Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.‐MS and microparticle enzyme immunoassay (MEIA)

British journal of clinical pharmacology, 1994-12, Vol.38 (6), p.567-571

1994

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Identification of drugs inhibiting the in vitro metabolism of tacrolimus by human liver microsomes

British journal of clinical pharmacology, 1996-03, Vol.41 (3), p.187-190

1996

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Growth characteristics and influence of antibiotics on rough/smooth phenotypic variants of Helicobacter pylori

European journal of clinical microbiology & infectious diseases, 1999-07, Vol.18 (7), p.490-495

1999

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Alternative cyclosporine metabolic pathways and toxicity

Clinical Biochemistry, 1995-12, Vol.28 (6), p.547-559

1995

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Drug metabolism in hepatocyte sandwich cultures of rats and humans

Helicobacter pylori causes DNA damage in gastric epithelial cells

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat

Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability

Cyclosporin metabolism in transplant patients

Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray- mass spectrometry

Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber

Helicobacter pylori augments the acid inhibitory effect of omeprazole on parietal cells and gastric H+/K+-ATPase

Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients

Interaction of Helicobacter pylori and its fatty acids with parietal cells and gastric H+/K(+)-ATPase

Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells

Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin

Structural elucidation by electrospray mass spectrometry: an approach to the in vitro metabolism of the macrolide immunosuppressant SDZ RAD

Structural identification of three metabolites and a degradation product of the macrolide immunosuppressant sirolimus (rapamycin) by electrospray-MS/MS after incubation with human liver microsomes

3-D Coculture of Hepatic Sinusoidal Cells with Primary Hepatocytes—Design of an Organotypical Model

Helicobacter pylori reduces intracellular glutathione in gastric epithelial cells

Automated simultaneous quantification of the immunosuppressants 40-O-(2-hydroxyethyl)rapamycin and cyclosporine in blood with electrospray-mass spectrometric detection

Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients

Automated, fast and sensitive quantification of drugs in blood by liquid chromatography–mass spectrometry with on-line extraction: immunosuppressants

Pharmacokinetics, dosing principles, and blood level monitoring of FK506

Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.‐MS and microparticle enzyme immunoassay (MEIA)

Identification of drugs inhibiting the in vitro metabolism of tacrolimus by human liver microsomes

Growth characteristics and influence of antibiotics on rough/smooth phenotypic variants of Helicobacter pylori

Alternative cyclosporine metabolic pathways and toxicity

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