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Interleukin-23 in the Pathogenesis of Inflammatory Bowel Disease and Implications for Therapeutic Intervention

Journal of Crohn's and colitis, 2022-05, Vol.16 (Supplement_2), p.ii3-ii19

2022

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C13orf31 (FAMIN) is a central regulator of immunometabolic function

Nature immunology, 2016-09, Vol.17 (9), p.1046

2016

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Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

The Journal of experimental medicine, 2009-08, Vol.206 (9), p.1883-1897

2009

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The immunopathogenesis of Crohn's disease: a three-stage model

Current opinion in immunology, 2009-10, Vol.21 (5), p.506-513

2009

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Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

Disease models & mechanisms, 2015-08, Vol.8 (8), p.817-829

2015

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ZODET: software for the identification, analysis and visualisation of outlier genes in microarray expression data

PloS one, 2014-01, Vol.9 (1), p.e81123-e81123

2014

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Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease

PloS one, 2009-11, Vol.4 (11), p.e7787-e7787

2009

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FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

Cell, 2020-01, Vol.180 (2), p.278-295.e23

2020

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A purine metabolic checkpoint that prevents autoimmunity and autoinflammation

Cell metabolism, 2022-01, Vol.34 (1), p.106-124.e10

2022

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Disruption of macrophage pro‐inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients

Immunology, 2015-01, Vol.144 (1), p.45-55

2015

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Lipidomic profiling in Crohn's disease: Abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition

The international journal of biochemistry & cell biology, 2012-11, Vol.44 (11), p.1839-1846

2012

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Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis

Inflammatory bowel diseases, 2014-10, Vol.20 (10), p.1802-1812

2014

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Crohn's Disease: an Immune Deficiency State

Clinical reviews in allergy & immunology, 2010-02, Vol.38 (1), p.20-31

2010

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Defective tumor necrosis factor release from Crohn's disease macrophages in response to toll‐like receptor activation: Relationship to phenotype and genome‐wide association susceptibility loci

Inflammatory bowel diseases, 2012-11, Vol.18 (11), p.2120-2127

2012

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Mo1786 ADAMDEC1: A Novel Molecule in Inflammation and Bowel Disease

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-685-S-685

2012

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Shotgun cholanomics of ileal fluid

Biochimie, 2013-03, Vol.95 (3), p.461-463

2013

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Tu1353 Mucosal mRNA Expression Profiling From the Terminal Ileum and Colon Reveals Under Expression of Claudin 8, a Tight Junction Molecule, as Potentially Causal in Ulcerative Colitis

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-809-S-809

2012

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Inflammatory bowel diseases in patients with adaptive and complement immunodeficiency disorders

Inflammatory bowel diseases, 2010-11, Vol.16 (11), p.1984-1992

2010

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Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis

Disease models & mechanisms, 2015-01

2015

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S1734 Abnormal TLR4-Mediated Interferon Response in Ulcerative Colitis

Gastroenterology (New York, N.Y. 1943), 2009, Vol.136 (5), p.A-259-A-259

2009

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Endoscopy, but not as we know it

British journal of hospital medicine (London, England : 2005), 2011-03, Vol.72 (3), p.174

2011

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Disruption of macrophage pro‐inflammatory cytokine release in C rohn's disease is associated with reduced optineurin expression in a subset of patients

Immunology, 2015-01, Vol.144 (1), p.45-55

2015

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Su1770 Fam5c, a Possible Causal Molecule in Ulcerative Colitis Revealed Through a Transcriptomic Analysis of the Bowel Mucosa

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-472-S-472

2013

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ZODET: Software for the Identification, Analysis and Visualisation of Outlier Genes in Microarray Expression Data: e81123

PloS one, 2014-01, Vol.9 (1)

2014

Volltextzugriff (PDF)

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Interleukin-23 in the Pathogenesis of Inflammatory Bowel Disease and Implications for Therapeutic Intervention

C13orf31 (FAMIN) is a central regulator of immunometabolic function

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

The immunopathogenesis of Crohn's disease: a three-stage model

Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

ZODET: software for the identification, analysis and visualisation of outlier genes in microarray expression data

Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

A purine metabolic checkpoint that prevents autoimmunity and autoinflammation

Disruption of macrophage pro‐inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

Lipidomic profiling in Crohn's disease: Abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition

Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis

Crohn's Disease: an Immune Deficiency State

Defective tumor necrosis factor release from Crohn's disease macrophages in response to toll‐like receptor activation: Relationship to phenotype and genome‐wide association susceptibility loci

Mo1786 ADAMDEC1: A Novel Molecule in Inflammation and Bowel Disease

Shotgun cholanomics of ileal fluid

Tu1353 Mucosal mRNA Expression Profiling From the Terminal Ileum and Colon Reveals Under Expression of Claudin 8, a Tight Junction Molecule, as Potentially Causal in Ulcerative Colitis

Inflammatory bowel diseases in patients with adaptive and complement immunodeficiency disorders

Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis

S1734 Abnormal TLR4-Mediated Interferon Response in Ulcerative Colitis

Endoscopy, but not as we know it

Disruption of macrophage pro‐inflammatory cytokine release in C rohn's disease is associated with reduced optineurin expression in a subset of patients

Su1770 Fam5c, a Possible Causal Molecule in Ulcerative Colitis Revealed Through a Transcriptomic Analysis of the Bowel Mucosa

ZODET: Software for the Identification, Analysis and Visualisation of Outlier Genes in Microarray Expression Data: e81123

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