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Need of orthogonal approaches in neurological disease modeling in mouse

Frontiers in molecular neuroscience, 2024-05, Vol.17, p.1399953-1399953

2024

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SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome

Nature communications, 2021-06, Vol.12 (1), p.4050-4050, Article 4050

2021

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SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

Neuron (Cambridge, Mass.), 2019-10, Vol.104 (2), p.271-289.e13

2019

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H3K36 Methylation in Neural Development and Associated Diseases

Frontiers in genetics, 2020-01, Vol.10, p.1291-1291

2020

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CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

Nature cell biology, 2012-09, Vol.14 (9), p.911

2012

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AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy

Molecular therapy, 2017-12, Vol.25 (12), p.2727-2742

2017

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SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub

Nature communications, 2018-06, Vol.9 (1), p.2192-13, Article 2192

2018

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Direct conversion of fibroblasts into functional astrocytes by defined transcription factors

Stem cell reports, 2015-01, Vol.4 (1), p.25-36

2015

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Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons

Genes & development, 2010-08, Vol.24 (16), p.1816-1826

2010

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Rare Does Not Mean Worthless: How Rare Diseases Have Shaped Neurodevelopment Research in the NGS Era

Biomolecules (Basel, Switzerland), 2021-11, Vol.11 (11), p.1713

2021

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The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways

Cerebral cortex (New York, N.Y. 1991), 2017-06, Vol.27 (6), p.3378-3396

2017

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CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene setd5 Leads to Social Impairments in Zebrafish

International journal of molecular sciences, 2022-12, Vol.24 (1), p.167

2022

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Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition

Nature communications, 2023-06, Vol.14 (1), p.3212-3212, Article 3212

2023

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TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering

Cell reports (Cambridge), 2019-10, Vol.29 (5), p.1130-1146.e8

2019

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MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis

Cell reports (Cambridge), 2016-10, Vol.17 (2), p.469-483

2016

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The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways

Cerebral cortex (New York, N.Y. 1991), 2017-12, Vol.27 (12), p.5715-5715

2017

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Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells

Nature communications, 2017-02, Vol.8 (1), p.14088-14088, Article 14088

2017

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SETD5 haploinsufficiency affects mitochondrial compartment in neural cells

Molecular autism, 2023-06, Vol.14 (1), p.20-20, Article 20

2023

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Editorial: Transcription and chromatin regulators in neurodevelopmental disorders

Frontiers in neuroscience, 2022-09, Vol.16, p.1023580-1023580

2022

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Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity

Developmental biology, 2009-10, Vol.334 (1), p.59-71

2009

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Zrf1 is required to establish and maintain neural progenitor identity

Genes & development, 2014-01, Vol.28 (2), p.182-197

2014

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ARX Regulates Cortical Intermediate Progenitor Cell Expansion and Upper Layer Neuron Formation Through Repression of Cdkn1c

Cerebral cortex (New York, N.Y. 1991), 2015-02, Vol.25 (2), p.322-335

2015

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TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway

Frontiers in cell and developmental biology, 2021-02, Vol.9, p.641410-641410

2021

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Epigenetic Mistakes in Neurodevelopmental Disorders

Journal of Molecular Neuroscience, 2017-04, Vol.61 (4), p.590-602

2017

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Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

Neuron (Cambridge, Mass.), 2008-10, Vol.60 (1), p.56-69

2008

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Need of orthogonal approaches in neurological disease modeling in mouse

SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome

SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

H3K36 Methylation in Neural Development and Associated Diseases

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy

SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub

Direct conversion of fibroblasts into functional astrocytes by defined transcription factors

Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons

Rare Does Not Mean Worthless: How Rare Diseases Have Shaped Neurodevelopment Research in the NGS Era

The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways

CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene setd5 Leads to Social Impairments in Zebrafish

Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition

TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering

MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis

The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways

Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells

SETD5 haploinsufficiency affects mitochondrial compartment in neural cells

Editorial: Transcription and chromatin regulators in neurodevelopmental disorders

Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity

Zrf1 is required to establish and maintain neural progenitor identity

ARX Regulates Cortical Intermediate Progenitor Cell Expansion and Upper Layer Neuron Formation Through Repression of Cdkn1c

TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway

Epigenetic Mistakes in Neurodevelopmental Disorders

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

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