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Dynamic Protein Acylation: New Substrates, Mechanisms, and Drug Targets

Trends in biochemical sciences (Amsterdam. Regular ed.), 2017-07, Vol.42 (7), p.566-581

2017

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Global profiling of co- and post-translationally N-myristoylated proteomes in human cells

Nature communications, 2014-09, Vol.5 (1), p.4919-4919, Article 4919

2014

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Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction

Nature communications, 2023-07, Vol.14 (1), p.4092-4092, Article 4092

2023

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Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

Nature chemistry, 2014-02, Vol.6 (2), p.112

2014

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Multifunctional Reagents for Quantitative Proteome-Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development

Angewandte Chemie (International ed.), 2015-05, Vol.54 (20), p.5948-5951

International ed. in English, 2015

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Proteasome activity contributes to pro-survival response upon mild mitochondrial stress in Caenorhabditis elegans

PLoS biology, 2021-07, Vol.19 (7), p.e3001302-e3001302

2021

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Site-Specifically Phosphorylated Lysine Peptides

Journal of the American Chemical Society, 2014-10, Vol.136 (39), p.13622-13628

2014

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Remote Activation of Host Cell DNA Synthesis in Uninfected Cells Signaled by Infected Cells in Advance of Virus Transmission

Journal of virology, 2015-11, Vol.89 (21), p.11107-11115

2015

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Spatial and Temporal Resolution of Global Protein Synthesis during HSV Infection Using Bioorthogonal Precursors and Click Chemistry

PLoS pathogens, 2016-10, Vol.12 (10), p.e1005927-e1005927

2016

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Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.940-951

2022

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Analysis of a fully infectious bio-orthogonally modified human virus reveals novel features of virus cell entry

PLoS pathogens, 2019-10, Vol.15 (10), p.e1007956

2019

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Chemoproteomic Evaluation of the Polyacetylene Callyspongynic Acid

Chemistry : a European journal, 2015-07, Vol.21 (30), p.10721-10728

2015

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Chemical proteomics: a powerful tool for exploring protein lipidation

Biochemical Society transactions, 2013-02, Vol.41 (1), p.56

2013

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Stabilization of Peptides for Intracellular Applications by Phosphoramidate-Linked Polyethylene Glycol Chains

Angewandte Chemie (International ed.), 2013-11, Vol.52 (45), p.11920-11924

International ed. in English, 2013

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Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics

Nature chemistry, 2019-06, Vol.11 (6), p.552

2019

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Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach

Molecular & cellular proteomics, 2016-02, Vol.15 (2), p.715-725

2016

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Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A[S]

Molecular & cellular proteomics, 2019-01, Vol.18 (1), p.115-126

2019

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OMA1 protease eliminates arrested protein import intermediates upon mitochondrial depolarization

The Journal of cell biology, 2024-05, Vol.223 (5)

2024

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AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (4), p.1414-1419

2019

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Myristoylation profiling in human cells and zebrafish

Data in brief, 2015-09, Vol.4 (C), p.379-383

2015

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A New Chemical Handle for Protein AMPylation at the Host-Pathogen Interface

Chembiochem : a European journal of chemical biology, 2012-01, Vol.13 (2), p.183-185

2012

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Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics

Chemistry & biology, 2015-08, Vol.22 (8), p.1008-1017

2015

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Global Analysis of Protein N-Myristoylation and Exploration of N-Myristoyltransferase as a Drug Target in the Neglected Human Pathogen Leishmania donovani

Chemistry & biology, 2015-03, Vol.22 (3), p.342-354

2015

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Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation

Journal of biophotonics, 2013-05, Vol.6 (5), p.398-408

2013

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Dynamic Protein Acylation: New Substrates, Mechanisms, and Drug Targets

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells

Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

Multifunctional Reagents for Quantitative Proteome-Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development

Proteasome activity contributes to pro-survival response upon mild mitochondrial stress in Caenorhabditis elegans

Site-Specifically Phosphorylated Lysine Peptides

Remote Activation of Host Cell DNA Synthesis in Uninfected Cells Signaled by Infected Cells in Advance of Virus Transmission

Spatial and Temporal Resolution of Global Protein Synthesis during HSV Infection Using Bioorthogonal Precursors and Click Chemistry

Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase

Analysis of a fully infectious bio-orthogonally modified human virus reveals novel features of virus cell entry

Chemoproteomic Evaluation of the Polyacetylene Callyspongynic Acid

Chemical proteomics: a powerful tool for exploring protein lipidation

Stabilization of Peptides for Intracellular Applications by Phosphoramidate-Linked Polyethylene Glycol Chains

Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics

Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach

Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A[S]

OMA1 protease eliminates arrested protein import intermediates upon mitochondrial depolarization

Trinucleotide mRNA Cap Analogue N6‑Benzylated at the Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo

AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis

Myristoylation profiling in human cells and zebrafish

A New Chemical Handle for Protein AMPylation at the Host-Pathogen Interface

Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics

Global Analysis of Protein N-Myristoylation and Exploration of N-Myristoyltransferase as a Drug Target in the Neglected Human Pathogen Leishmania donovani

Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation

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