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The Discovery of Novel Vasopressin V1b Receptor Ligands for Pharmacological, Functional and Structural Investigations

Journal of neuroendocrinology, 2004-04, Vol.16 (4), p.356-361

2004

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PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice

Journal of the American Society of Nephrology, 2007-06, Vol.18 (6), p.1740-1753

2007

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Coupling of endothelin B receptors to the calcium pump and phospholipase C via Gs and Gq in rat liver

The Journal of biological chemistry, 1994-01, Vol.269 (3), p.1845-1851

1994

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Key Amino Acids Located within the Transmembrane Domains 5 and 7 Account for the Pharmacological Specificity of the Human V1b Vasopressin Receptor

Molecular endocrinology (Baltimore, Md.), 2004-11, Vol.18 (11), p.2777-2789

2004

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Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors

The Journal of clinical investigation, 1993-07, Vol.92 (1), p.224-231

1993

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Immunomodulation and infection: identification of small molecule TLR3 blockers to combat deleterious inflammation in pneumonia

Critical care (London, England), 2014-12, Vol.18 (S2), p.P55-P55, Article P55

2014

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Safety, tolerability, and pharmacokinetics of SR 49059, a V1a vasopressin receptor antagonist, after repeated oral administration in healthy volunteers

Advances in experimental medicine and biology, 1998, Vol.449, p.455

1998

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Nonpeptide vasopressin receptor antagonists: development of selective and orally active V1a, V2 and V1b receptor ligands

Progress in brain research, 2002, Vol.139, p.197-210

2002

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Characterization of SR 121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist

The Journal of clinical investigation, 1996-12, Vol.98 (12), p.2729-2738

1996

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V2 receptor antagonism of DDAVP-induced release of hemostasis factors in conscious dogs

The Journal of pharmacology and experimental therapeutics, 1997-08, Vol.282 (2), p.597

1997

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Effects of SR 49059, a non-peptide antagonist of vasopressin V1a receptors, on vasopressin-induced coronary vasoconstriction in conscious rabbits

Fundamental & clinical pharmacology, 1995-01, Vol.9 (1), p.17-24

1995

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Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors

The Journal of clinical investigation, 1996-12, Vol.98 (12), p.2771-2778

1996

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Nonpeptide antagonists for vasopressin receptors. Pharmacology of SR 121463A, a new potent and highly selective V2 receptor antagonist

Advances in experimental medicine and biology, 1998, Vol.449, p.427

Serradeil-Le Gal, C

1998

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Acute renal response to the non-peptide vasopressin V2-receptor antagonist SR 121463B in anesthetized rats

Naunyn-Schmiedeberg's archives of pharmacology, 2000-09, Vol.362 (3), p.201-207

2000

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An Overview of SR121463, a Selective Non‐Peptide Vasopressin V2 Receptor Antagonist

Cardiovascular drug reviews, 2001-09, Vol.19 (3), p.201-214

Gal, C. Serradeil‐Le

2001

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Benzophenanthridine alkaloids isolated from Eschscholtzia californica cell suspension cultures interact with vasopressin (V1) receptors

Planta medica, 1992-02, Vol.58 (1), p.35-38

1992

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Single Amino Acid Substitutions and Deletions That Alter the G Protein Coupling Properties of the V2 Vasopressin Receptor Identified in Yeast by Receptor Random Mutagenesis

The Journal of biological chemistry, 2001-08, Vol.276 (31), p.29382-29392

2001

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SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor

The Journal of pharmacology and experimental therapeutics, 2004-04, Vol.309 (1), p.414

2004

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Vasopressin: A potent autocrine/paracrine regulator of mammal adrenal functions

Endocrine research, 1998-01, Vol.24 (3-4), p.703-710

1998

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Effect of a new, potent, non-peptide V1a vasopressin antagonist, SR 49059, on the binding and the mitogenic activity of vasopressin on Swiss 3T3 cells

Biochemical pharmacology, 1994-02, Vol.47 (4), p.633-641

1994

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Characterization of NPY receptors controlling lipolysis and leptin secretion in human adipocytes

FEBS letters, 2000-06, Vol.475 (2), p.150-156

2000

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Characterization and localization of leptin receptors in the rat kidney

FEBS letters, 1997-03, Vol.404 (2), p.185-191

1997

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The Relationship Among Carbon Dioxide Pneumoperitoneum, Vasopressin Release, and Hemodynamic Changes

Anesthesia and analgesia, 1999-08, Vol.89 (2), p.278-283

1999

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Differential Sensitivity to Cardiotonic Drugs of Cyclic AMP Phosphodiesterases Isolated from Canine Ventricular and Sinoatrial-Enriched Tissues

Journal of cardiovascular pharmacology, 1989-08, Vol.14 (2), p.213-220

1989

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Binding properties of a selective tritiated vasopressin V2 receptor antagonist, [3H]-SR 121463

Kidney international, 2000-10, Vol.58 (4), p.1613-1622

2000

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The Discovery of Novel Vasopressin V1b Receptor Ligands for Pharmacological, Functional and Structural Investigations

PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice

Coupling of endothelin B receptors to the calcium pump and phospholipase C via Gs and Gq in rat liver

Key Amino Acids Located within the Transmembrane Domains 5 and 7 Account for the Pharmacological Specificity of the Human V1b Vasopressin Receptor

Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors

Immunomodulation and infection: identification of small molecule TLR3 blockers to combat deleterious inflammation in pneumonia

Safety, tolerability, and pharmacokinetics of SR 49059, a V1a vasopressin receptor antagonist, after repeated oral administration in healthy volunteers

Nonpeptide vasopressin receptor antagonists: development of selective and orally active V1a, V2 and V1b receptor ligands

Characterization of SR 121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist

V2 receptor antagonism of DDAVP-induced release of hemostasis factors in conscious dogs

Effects of SR 49059, a non-peptide antagonist of vasopressin V1a receptors, on vasopressin-induced coronary vasoconstriction in conscious rabbits

Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors

Nonpeptide antagonists for vasopressin receptors. Pharmacology of SR 121463A, a new potent and highly selective V2 receptor antagonist

Acute renal response to the non-peptide vasopressin V2-receptor antagonist SR 121463B in anesthetized rats

An Overview of SR121463, a Selective Non‐Peptide Vasopressin V2 Receptor Antagonist

Benzophenanthridine alkaloids isolated from Eschscholtzia californica cell suspension cultures interact with vasopressin (V1) receptors

Single Amino Acid Substitutions and Deletions That Alter the G Protein Coupling Properties of the V2 Vasopressin Receptor Identified in Yeast by Receptor Random Mutagenesis

SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor

Vasopressin: A potent autocrine/paracrine regulator of mammal adrenal functions

Effect of a new, potent, non-peptide V1a vasopressin antagonist, SR 49059, on the binding and the mitogenic activity of vasopressin on Swiss 3T3 cells

Characterization of NPY receptors controlling lipolysis and leptin secretion in human adipocytes

Characterization and localization of leptin receptors in the rat kidney

The Relationship Among Carbon Dioxide Pneumoperitoneum, Vasopressin Release, and Hemodynamic Changes

Differential Sensitivity to Cardiotonic Drugs of Cyclic AMP Phosphodiesterases Isolated from Canine Ventricular and Sinoatrial-Enriched Tissues

Binding properties of a selective tritiated vasopressin V2 receptor antagonist, [3H]-SR 121463

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