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2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.548-565

2001

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A Prodrug Form of a Plasmodium falciparum Glutathione Reductase Inhibitor Conjugated with a 4-Anilinoquinoline

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4268-4276

2001

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Trypanosoma cruzi Prolyl Oligopeptidase Tc80 Is Involved in Nonphagocytic Mammalian Cell Invasion by Trypomastigotes

The Journal of biological chemistry, 2001-12, Vol.276 (50), p.47078-47086

2001

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Design, synthesis and in vitro antimalarial activity of an acylhydrazone library

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (1), p.31-35

2006

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Synthesis and in Vitro and in Vivo Antimalarial Activity of New 4-Anilinoquinolines

Journal of medicinal chemistry, 2001-08, Vol.44 (17), p.2827-2833

2001

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Territoires et économies

Théophane Nicolas, Aurélie Salavert (dir.)

2010

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Antiplasmodial Activity and Cytotoxicity of Bis-, Tris-, and Tetraquinolines with Linear or Cyclic Amino Linkers

Journal of medicinal chemistry, 2001-05, Vol.44 (11), p.1658-1665

2001

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Lacrimal gland PKC isoforms are differentially involved in agonist-induced protein secretion

American Journal of Physiology: Cell Physiology, 1997-01, Vol.272 (1), p.C263-C269

1997

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Parallel Synthesis and Anti-Malarial Activity of a Sulfonamide Library

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2595-2598

2002

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Truncated beta‐amyloid peptide species in pre‐clinical Alzheimer's disease as new targets for the vaccination approach

Journal of neurochemistry, 2003-06, Vol.85 (6), p.1581-1591

2003

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Synthesis, Antimalarial Activity, and Molecular Modeling of New Pyrrolo[1,2-a]quinoxalines, Bispyrrolo[1,2-a]quinoxalines, Bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and Bispyrrolo[1,2-a]thieno[3,2-e]pyrazines

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1997-2009

2004

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Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro

Cell biology and toxicology, 1997-03, Vol.13 (3), p.141-153

1997

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Trypanothione reductase inhibition/trypanocidal activity relationships in a 1,4-bis(3-aminopropyl)piperazine series

Bioorganic & medicinal chemistry, 2000, Vol.8 (1), p.95-103

2000

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Design, synthesis and antimalarial activity of a glyoxylylhydrazone library

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4439-4443

2004

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Purification and characterization of a trypanothione-glutathione thioltransferase from Trypanosoma cruzi

Biochemical journal, 1995-09, Vol.310 ( Pt 2) (2), p.433-437

1995

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Antimalarial in-vivo activity of bis(9-amino-6-chloro-2-methoxyacridines)

Journal of pharmacy and pharmacology, 2001-07, Vol.53 (7), p.935-938

2001

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Synthesis and in Vitro and in Vivo Antimalarial Activity of N 1 -(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives

Journal of medicinal chemistry, 2003-02, Vol.46 (4), p.542-557

2003

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Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin

Nature medicine, 2004-09, Vol.10 (9), p.935-941

2004

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Mycobacterial Heparin-Binding Hemagglutinin and Laminin-Binding Protein Share Antigenic Methyllysines That Confer Resistance to Proteolysis

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10759-10764

2002

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Antimalarial, Antitrypanosomal, and Antileishmanial Activities and Cytotoxicity of Bis(9-amino-6-chloro-2-methoxyacridines): Influence of the Linker

Journal of medicinal chemistry, 2000-07, Vol.43 (14), p.2646-2654

2000

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Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase

Biochimie, 2007-03, Vol.89 (3), p.337-346

2007

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Conversion of Sterically Hindered Diacylated 1,2-Phenylenediamines into 2-Substituted Benzimidazoles

Chemical and Pharmaceutical Bulletin, 2005, Vol.53(5), pp.492-497

2005

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Reduction of a Trisulfide Derivative of Glutathione by Glutathione Reductase

Biochemical and biophysical research communications, 1994-08, Vol.202 (3), p.1380-1386

1994

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Design, synthesis and antimalarial activity of novel, quinoline-Based, zinc metallo-aminopeptidase inhibitors

Bioorganic & medicinal chemistry letters, 2003-08, Vol.13 (16), p.2659-2662

2003

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Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs

Journal of medicinal chemistry, 1993-04, Vol.36 (7), p.826-830

1993

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2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

A Prodrug Form of a Plasmodium falciparum Glutathione Reductase Inhibitor Conjugated with a 4-Anilinoquinoline

Trypanosoma cruzi Prolyl Oligopeptidase Tc80 Is Involved in Nonphagocytic Mammalian Cell Invasion by Trypomastigotes

Design, synthesis and in vitro antimalarial activity of an acylhydrazone library

Synthesis and in Vitro and in Vivo Antimalarial Activity of New 4-Anilinoquinolines

Territoires et économies

Antiplasmodial Activity and Cytotoxicity of Bis-, Tris-, and Tetraquinolines with Linear or Cyclic Amino Linkers

Lacrimal gland PKC isoforms are differentially involved in agonist-induced protein secretion

Parallel Synthesis and Anti-Malarial Activity of a Sulfonamide Library

Truncated beta‐amyloid peptide species in pre‐clinical Alzheimer's disease as new targets for the vaccination approach

Synthesis, Antimalarial Activity, and Molecular Modeling of New Pyrrolo[1,2-a]quinoxalines, Bispyrrolo[1,2-a]quinoxalines, Bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and Bispyrrolo[1,2-a]thieno[3,2-e]pyrazines

Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro

Trypanothione reductase inhibition/trypanocidal activity relationships in a 1,4-bis(3-aminopropyl)piperazine series

Design, synthesis and antimalarial activity of a glyoxylylhydrazone library

Purification and characterization of a trypanothione-glutathione thioltransferase from Trypanosoma cruzi

Antimalarial in-vivo activity of bis(9-amino-6-chloro-2-methoxyacridines)

Synthesis and in Vitro and in Vivo Antimalarial Activity of N 1 -(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives

Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin

Mycobacterial Heparin-Binding Hemagglutinin and Laminin-Binding Protein Share Antigenic Methyllysines That Confer Resistance to Proteolysis

Antimalarial, Antitrypanosomal, and Antileishmanial Activities and Cytotoxicity of Bis(9-amino-6-chloro-2-methoxyacridines): Influence of the Linker

Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase

Conversion of Sterically Hindered Diacylated 1,2-Phenylenediamines into 2-Substituted Benzimidazoles

Reduction of a Trisulfide Derivative of Glutathione by Glutathione Reductase

Design, synthesis and antimalarial activity of novel, quinoline-Based, zinc metallo-aminopeptidase inhibitors

Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs

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