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Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans

Nature medicine, 2018-11, Vol.24 (11), p.1683-1690

2018

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Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis

Nature communications, 2021-07, Vol.12 (1), p.4559-4559, Article 4559

2021

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A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

The Journal of experimental medicine, 2019-12, Vol.216 (12), p.2778-2799

2019

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In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Cell stem cell, 2016-07, Vol.19 (1), p.107-119

2016

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Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy

Nature communications, 2023-05, Vol.14 (1), p.3068-3068, Article 3068

2023

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Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning

Frontiers in endocrinology (Lausanne), 2024-09, Vol.15, p.1450349

2024

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Current Approaches and Future Perspectives for In Vivo Clonal Tracking of Hematopoietic Cells

Current gene therapy, 2016-01, Vol.16 (3), p.184-193

2016

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Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis

PloS one, 2011-09, Vol.6 (9), p.e25162-e25162

2011

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In vivo dynamics of human hematopoietic stem cells: novel concepts and future directions

Blood advances, 2019-06, Vol.3 (12), p.1916-1924

2019

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Exploitation of circulating CD34+ cells and non-genotoxic conditioning to overcome major limitations to treatment for autosomal recessive osteopetrosis

Bone Reports, 2020-10, Vol.13, p.100596, Article 100596

2020

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Genetic engineering meets hematopoietic stem cell biology for next-generation gene therapy

Cell stem cell, 2023-05, Vol.30 (5), p.549-570

2023

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Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress

Nature immunology, 2022-10, Vol.23 (10), p.1470-1483

2022

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Tracking hematopoietic stem cell evolution in a Wiskott–Aldrich clinical trial

The annals of applied statistics, 2023-09, Vol.17 (3)

2023

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Transcriptomic analysis of BM-MSCs identified EGR1 as a transcription factor to fully exploit their therapeutic potential

Biochimica et biophysica acta. Molecular cell research, 2024-12, Vol.1871 (8), p.119818, Article 119818

2024

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In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells

Science translational medicine, 2015-02, Vol.7 (273), p.273ra13

2015

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T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Blood, 2018-11, Vol.132 (22), p.2362-2374

2018

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Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs

Molecular therapy, 2023-01, Vol.31 (1), p.230-248

2023

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Bayesian networks for cell differentiation process assessment

Stat (International Statistical Institute), 2020, Vol.9 (1), p.n/a

2020

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Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs

Molecular therapy, 2022-10, Vol.30 (10), p.3333-3333

2022

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Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders

Science translational medicine, 2023-05, Vol.15 (698), p.eade3856

2023

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Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study

The Lancet. Haematology, 2019-05, Vol.6 (5), p.e239-e253

2019

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Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans

Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy

Hematopoietic Tumors in a Mouse Model of X-linked Chronic Granulomatous Disease after Lentiviral Vector-Mediated Gene Therapy

Expanded circulating hematopoietic stem/progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis

Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning

Current Approaches and Future Perspectives for In Vivo Clonal Tracking of Hematopoietic Cells

Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis

In vivo dynamics of human hematopoietic stem cells: novel concepts and future directions

S250: UNVEILING THE BIOLOGICAL ROLE OF PERIPHERAL BLOOD HUMAN CIRCULATING HEMATOPOIETIC STEM AND PROGENITOR CELLS

Exploitation of circulating CD34+ cells and non-genotoxic conditioning to overcome major limitations to treatment for autosomal recessive osteopetrosis

Genetic engineering meets hematopoietic stem cell biology for next-generation gene therapy

Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress

Tracking hematopoietic stem cell evolution in a Wiskott–Aldrich clinical trial

Transcriptomic analysis of BM-MSCs identified EGR1 as a transcription factor to fully exploit their therapeutic potential

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs

Bayesian networks for cell differentiation process assessment

Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs

Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders

Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study

Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

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