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function of RNA-binding proteins at the synapse: implications for neurodegeneration

Cellular and Molecular Life Sciences, 2015-10, Vol.72 (19), p.3621-3635

2015

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Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration

The Journal of biological chemistry, 2012-09, Vol.287 (39), p.32298-32306

2012

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TDP-43 Is Directed to Stress Granules by Sorbitol, a Novel Physiological Osmotic and Oxidative Stressor

Molecular and Cellular Biology, 2011-03, Vol.31 (5), p.1098-1108

2011

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Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes

The Journal of biological chemistry, 2011-01, Vol.286 (2), p.1204-1215

2011

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Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease

Frontiers in molecular neuroscience, 2022-10, Vol.15, p.1000183-1000183

2022

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TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development

The Journal of biological chemistry, 2010-02, Vol.285 (9), p.6826-6834

2010

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FUS contributes to mTOR-dependent inhibition of translation

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.18459-18473

2020

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GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2068

2024

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (44), p.15613-15613

2014

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TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration

Biological chemistry, 2012-07, Vol.393 (7), p.589-594

2012

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Metabolic Networks Influencing Skeletal Muscle Fiber Composition

Frontiers in cell and developmental biology, 2018-09, Vol.6, p.125-125

2018

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Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD

The Journal of experimental medicine, 2014-09, Vol.211 (10), p.1937-1945

2014

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hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated

Frontiers in neuroscience, 2021-09, Vol.15, p.724307-724307

2021

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Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition

Acta neuropathologica communications, 2023-11, Vol.11 (1), p.1-182, Article 182

2023

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TDP-43 aggregation in neurodegeneration: Are stress granules the key?

Brain research, 2012-06, Vol.1462, p.16-25

2012

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Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways

Biological psychiatry (1969), 2021-08, Vol.90 (3), p.194-205

2021

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Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS

Cell stress & chaperones, 2024-06, Vol.29 (3), p.359-380

2024

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Reversal of cognitive deficits in FUSR521G amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction

Neurotherapeutics, 2024-09, Vol.21 (5), p.e00388, Article e00388

2024

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Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105475, Article 105475

2023

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Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia

The Journal of biological chemistry, 2011-05, Vol.286 (18), p.16101-16108

2011

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Haloperidol induces the nuclear translocation of phosphatidylinositol 3′-kinase to disrupt Akt phosphorylation in PC12 cells

Journal of psychiatry & neuroscience, 2007-09, Vol.32 (5), p.323-330

2007

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NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis

eNeuro, 2022-03, Vol.9 (2), p.ENEURO.0317-21.2022

2022

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A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics

Acta neuropathologica communications, 2022-02, Vol.10 (1), p.20-20, Article 20

2022

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γ-Secretase-regulated Proteolysis of the Notch Receptor by Mitochondrial Intermediate Peptidase

The Journal of biological chemistry, 2011-08, Vol.286 (31), p.27447-27453

2011

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Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-ÎºB inhibition

Acta neuropathologica communications, 2023-11, Vol.11 (1)

2023

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function of RNA-binding proteins at the synapse: implications for neurodegeneration

Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration

TDP-43 Is Directed to Stress Granules by Sorbitol, a Novel Physiological Osmotic and Oxidative Stressor

Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes

Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease

TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development

FUS contributes to mTOR-dependent inhibition of translation

GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration

Metabolic Networks Influencing Skeletal Muscle Fiber Composition

Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD

hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated

Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition

TDP-43 aggregation in neurodegeneration: Are stress granules the key?

Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways

Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS

Reversal of cognitive deficits in FUSR521G amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia

Haloperidol induces the nuclear translocation of phosphatidylinositol 3′-kinase to disrupt Akt phosphorylation in PC12 cells

NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis

A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics

γ-Secretase-regulated Proteolysis of the Notch Receptor by Mitochondrial Intermediate Peptidase

Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-ÎºB inhibition

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