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Mechanopharmacology of Rho-kinase antagonism in airway smooth muscle and potential new therapy for asthma

Pharmacological research, 2020-09, Vol.159, p.104995-104995, Article 104995

2020

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Molecular Events of the Crossbridge Cycle Reflected in the Force-Velocity Relationship of Activated Muscle

Frontiers in physiology, 2022-03, Vol.13, p.846284-846284

2022

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p116Rip promotes myosin phosphatase activity in airway smooth muscle cells

Journal of cellular physiology, 2020-01, Vol.235 (1), p.114-127

2020

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Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Trends in pharmacological sciences (Regular ed.), 2016-02, Vol.37 (2), p.87-100

2016

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Rho-Kinase Inhibition of Active Force and Passive Tension in Airway Smooth Muscle: A Strategy for Treating Airway Hyperresponsiveness in Asthma

Biology (Basel, Switzerland), 2024-02, Vol.13 (2), p.115

2024

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Myosin filament assembly in an ever-changing myofilament lattice of smooth muscle

American Journal of Physiology: Cell Physiology, 2005-12, Vol.289 (6), p.C1363-C1368

Seow, Chun Y

2005

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Purification of Myosin from Bovine Tracheal Smooth Muscle, Filament Formation and Endogenous Association of Its Regulatory Complex

Cells (Basel, Switzerland), 2023-02, Vol.12 (3), p.514

2023

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Passive stiffness of airway smooth muscle: The next target for improving airway distensibility and treatment for asthma?

Pulmonary pharmacology & therapeutics, 2013-02, Vol.26 (1), p.37-41

Seow, Chun Y

2013

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The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics

PloS one, 2017-03, Vol.12 (3), p.e0171728-e0171728

2017

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Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease

PloS one, 2015-03, Vol.10 (3), p.e0119717-e0119717

2015

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Filament evanescence of myosin II and smooth muscle function

The Journal of general physiology, 2021-03, Vol.153 (3), p.1

2021

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Hill's equation of muscle performance and its hidden insight on molecular mechanisms

The Journal of general physiology, 2013-12, Vol.142 (6), p.561-573

Seow, Chun Y

2013

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Potentiation of active force by cyclic strain in sheep carotid arterial smooth muscle

Journal of applied physiology (1985), 2023-12, Vol.135 (6), p.1243

2023

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Gene expression analysis in asthma using a targeted multiplex array

BMC pulmonary medicine, 2017-12, Vol.17 (1), p.189-189, Article 189

2017

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Emergence of airway smooth muscle functions related to structural malleability

Journal of applied physiology (1985), 2011-04, Vol.110 (4), p.1130-1135

2011

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Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment?

Journal of applied physiology (1985), 2012-02, Vol.112 (3), p.337-346

2012

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Rho-kinase mediated cytoskeletal stiffness in skinned smooth muscle

Journal of applied physiology (1985), 2013-11, Vol.115 (10), p.1540-1552

2013

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The Force Awakens in the Cytoskeleton: The Saga of a Shape-Shifter

American journal of respiratory cell and molecular biology, 2020-05, Vol.62 (5), p.550-551

2020

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Sustained contractile force regulated by rho-kinase and protein kinase C in sheep carotid arterial smooth muscle

Journal of applied physiology (1985), 2023-01, Vol.134 (1), p.152-159

2023

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Reply from Chun Y. Seow

The Journal of physiology, 2015-01, Vol.593 (2), p.477-479

Seow, Chun Y.

2015

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p116 Rip promotes myosin phosphatase activity in airway smooth muscle cells

Journal of cellular physiology, 2020-01, Vol.235 (1), p.114-127

2020

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Lung resistance and elastance are different in ex vivo sheep lungs ventilated by positive and negative pressures

American journal of physiology. Lung cellular and molecular physiology, 2022-05, Vol.322 (5), p.L673-L682

2022

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The Huxley crossbridge model as the basic mechanism for airway smooth muscle contraction

American journal of physiology. Lung cellular and molecular physiology, 2019-08, Vol.317 (2), p.L235-L246

2019

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Airway diameter at different transpulmonary pressures in ex vivo sheep lungs: implications for deep inspiration-induced bronchodilation and bronchoprotection

American journal of physiology. Lung cellular and molecular physiology, 2021-10, Vol.321 (4), p.L663-L674

2021

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Airway and parenchymal tissue resistance and elastance in ex vivo sheep lungs: Effects of bronchochallenge and deep inspiration

American journal of physiology. Lung cellular and molecular physiology, 2022-06, Vol.322 (6), p.L882-L889

2022

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Mechanopharmacology of Rho-kinase antagonism in airway smooth muscle and potential new therapy for asthma

Molecular Events of the Crossbridge Cycle Reflected in the Force-Velocity Relationship of Activated Muscle

p116Rip promotes myosin phosphatase activity in airway smooth muscle cells

Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Rho-Kinase Inhibition of Active Force and Passive Tension in Airway Smooth Muscle: A Strategy for Treating Airway Hyperresponsiveness in Asthma

Myosin filament assembly in an ever-changing myofilament lattice of smooth muscle

Purification of Myosin from Bovine Tracheal Smooth Muscle, Filament Formation and Endogenous Association of Its Regulatory Complex

Passive stiffness of airway smooth muscle: The next target for improving airway distensibility and treatment for asthma?

The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics

Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease

Filament evanescence of myosin II and smooth muscle function

Hill's equation of muscle performance and its hidden insight on molecular mechanisms

Potentiation of active force by cyclic strain in sheep carotid arterial smooth muscle

Gene expression analysis in asthma using a targeted multiplex array

Emergence of airway smooth muscle functions related to structural malleability

Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment?

Rho-kinase mediated cytoskeletal stiffness in skinned smooth muscle

The Force Awakens in the Cytoskeleton: The Saga of a Shape-Shifter

Sustained contractile force regulated by rho-kinase and protein kinase C in sheep carotid arterial smooth muscle

Reply from Chun Y. Seow

p116 Rip promotes myosin phosphatase activity in airway smooth muscle cells

Lung resistance and elastance are different in ex vivo sheep lungs ventilated by positive and negative pressures

The Huxley crossbridge model as the basic mechanism for airway smooth muscle contraction

Airway diameter at different transpulmonary pressures in ex vivo sheep lungs: implications for deep inspiration-induced bronchodilation and bronchoprotection

Airway and parenchymal tissue resistance and elastance in ex vivo sheep lungs: Effects of bronchochallenge and deep inspiration

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