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Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain

Neurochemistry international, 2014-04, Vol.69, p.35-40

2014

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Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson’s Disease

The New England journal of medicine, 2020-05, Vol.382 (20), p.1926-1932

2020

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Brain cells derived from Alzheimer's disease patients have multiple specific innate abnormalities in energy metabolism

Molecular psychiatry, 2021-10, Vol.26 (10), p.5702-5714

2021

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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Journal of biochemistry (Tokyo), 2015-06, Vol.157 (6), p.485-495

2015

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Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells

Nature protocols, 2022-03, Vol.17 (3), p.890-909

2022

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miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling

Neurobiology of aging, 2014-07, Vol.35 (7), p.1712-1721

2014

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Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease

Brain (London, England : 1878), 2015-10, Vol.138 (Pt 10), p.3030-3047

2015

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LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Nature communications, 2015-09, Vol.6 (1), p.8255-8255, Article 8255

2015

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Enhancement of BACE1 Activity by p25/Cdk5-Mediated Phosphorylation in Alzheimer's Disease

PloS one, 2015-08, Vol.10 (8), p.e0136950-e0136950

2015

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HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice

Experimental Neurobiology, 2019, 28(4), , pp.504-515

2019

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Generation of a human iPSC line from a Parkinson’s disease patient with a novel CHCHD2 mutation (p.R145Q)

Stem cell research, 2024-06, Vol.77, p.103419, Article 103419

2024

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Efficient Induction of Oligodendrocytes from Human Embryonic Stem Cells

Stem cells (Dayton, Ohio), 2007-02, Vol.25 (2), p.419-424

2007

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Dyrk1A Phosphorylates p53 and Inhibits Proliferation of Embryonic Neuronal Cells

The Journal of biological chemistry, 2010-10, Vol.285 (41), p.31895-31906

2010

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Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice

Experimental neurology, 2005-06, Vol.193 (2), p.469-480

2005

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Proteasome activator enhances survival of Huntington's disease neuronal model cells

PloS one, 2007-02, Vol.2 (2), p.e238-e238

2007

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G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

BioMed research international, 2016-01, Vol.2016, p.7917128-8

2016

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Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.856-868

2021

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Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson's Disease Model Mice

Biomolecules & Therapeutics, 2021, 29(5), , pp.483-491

2021

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Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3455

2020

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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Parkinson's disease, 2018-01, Vol.2018, p.1241757-9

2018

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Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice

Biomolecules & therapeutics, 2021-09, Vol.29 (5), p.483-491

2021

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Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington’s disease model mice

Biochemical and biophysical research communications, 2014-01, Vol.443 (2), p.706-711

2014

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Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell‐specific manner

Journal of neurochemistry, 2003-05, Vol.85 (3), p.622-634

2003

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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Animal Cells and Systems, 2018, 22(5), , pp.273-280

2018

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SCAMP5 Links Endoplasmic Reticulum Stress to the Accumulation of Expanded Polyglutamine Protein Aggregates via Endocytosis Inhibition

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11318-11325

2009

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Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain

Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson’s Disease

Brain cells derived from Alzheimer's disease patients have multiple specific innate abnormalities in energy metabolism

An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells

miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling

Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease

LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Enhancement of BACE1 Activity by p25/Cdk5-Mediated Phosphorylation in Alzheimer's Disease

HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice

Generation of a human iPSC line from a Parkinson’s disease patient with a novel CHCHD2 mutation (p.R145Q)

Efficient Induction of Oligodendrocytes from Human Embryonic Stem Cells

Dyrk1A Phosphorylates p53 and Inhibits Proliferation of Embryonic Neuronal Cells

Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice

Proteasome activator enhances survival of Huntington's disease neuronal model cells

G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model

Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson's Disease Model Mice

Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice

Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington’s disease model mice

Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell‐specific manner

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

SCAMP5 Links Endoplasmic Reticulum Stress to the Accumulation of Expanded Polyglutamine Protein Aggregates via Endocytosis Inhibition

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