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Molecular mechanisms of avian immunoglobulin gene diversification and prospect for industrial applications

Frontiers in immunology, 2024-09, Vol.15, p.1453833

2024

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TET3 dioxygenase modulates gene conversion at the avian immunoglobulin variable region via demethylation of non‐CpG sites in pseudogene templates

Genes to cells : devoted to molecular & cellular mechanisms, 2021-03, Vol.26 (3), p.121-135

2021

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Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line

Cellular & molecular immunology, 2021-06, Vol.18 (6), p.1545-1561

2021

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B Cell-Based Seamless Engineering of Antibody Fc Domains

PloS one, 2016-12, Vol.11 (12), p.e0167232-e0167232

2016

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Fast-tracking antibody maturation using a B cell-based display system

mAbs, 2022-12, Vol.14 (1), p.2122275

2022

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Rapid generation of specific antibodies by enhanced homologous recombination

Nature biotechnology, 2005-06, Vol.23 (6), p.731-735

2005

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Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion

International immunology, 2008-02, Vol.20 (2), p.277-284

2008

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Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40

Genes to cells : devoted to molecular & cellular mechanisms, 2008-03, Vol.13 (3), p.255-268

2008

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Fabrication of a Novel Photoelectric Conversion Device Consisting of a Poly-3-dodecylthiophene Film and C60 Fullerene–Ethylenediamine Nanoparticles

Chemistry letters, 2007-07, Vol.36 (7), p.934-935

2007

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A DNA unwinding factor involved in DNA replication in cell-free extracts of Xenopus eggs

Current biology, 1999-04, Vol.9 (7), p.341-351

1999

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Modulation of Immunoglobulin Gene Conversion in Chicken DT40 by Enhancing Histone Acetylation, and its Application to Antibody Engineering

Biotechnology & genetic engineering reviews, 2007-01, Vol.24 (1), p.179-194

2007

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An ex vivo method for rapid generation of monoclonal antibodies (ADLib system)

Nature protocols, 2006-11, Vol.1 (3), p.1502-1506

2006

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Drug discovery using new genome reorganization and genome synthesis techniques

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2023, Vol.97, p.2

2023

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ADLib System for Rapid and Flexible Design of Monoclonal Antibodies

Yakugaku zasshi, 2007-01, Vol.127 (1), p.81-89

2007

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ADLib System for Rapid and Flexible Design of Monoclonal Antibodies

YAKUGAKU ZASSHI, 2007/01/01, Vol.127(1), pp.81-89

2007

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p97 ATPase, an ATPase involved in membrane fusion, interacts with DNA unwinding factor (DUF) that functions in DNA replication

FEBS letters, 2000-01, Vol.466 (2), p.287-291

2000

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Incorporation of DUF/FACT into chromatin enhances the accessibility of nucleosomal DNA

Biochemical and biophysical research communications, 2003-03, Vol.303 (1), p.8-13

2003

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Fast-tracking antibody maturation using a B cell-based display system

mAbs, 2022, Vol.14 (1)

2022

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ADLibシステムを用いたモノクローナル抗体の迅速作製

YAKUGAKU ZASSHI, 2007/01/01, Vol.127(1), pp.81-89

2007

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ADLib System for Rapid and Flexible Design of Monoclonal Antibodies

ChemInform, 2007-05, Vol.38 (19), p.no-no

2007

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Simple Fabrication of [C60]Fullerene Assemblies by using Linker Molecules and their Photoelectrochemical Application

Meeting abstracts (Electrochemical Society), 2008-05, Vol.MA2008-01 (35), p.1127-1127

2008

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Control of Lanthanide Coordination Environment: Synthesis, Structure, and Oxygen-Sensitive Luminescence Properties of an Eight-Coordinate Tb(III) Complex

Inorganic chemistry, 2016-07, Vol.55 (13), p.6609-6615

2016

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An oxygen-sensitive luminescent Dy(iii) complex

Dalton transactions : an international journal of inorganic chemistry, 2016-06, Vol.45 (23), p.9492-9496

2016

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Value of 3-Dimensional Speckle Tracking Echocardiography in the Prediction of Microvascular Obstruction and Left Ventricular Remodeling in Patients With ST-Elevation Myocardial Infarction

Circulation Journal, 2017/02/24, Vol.81(3), pp.353-360

2017

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Luminescent Tb() and Sm() complexes with a 1,4,7-triazacyclononane-based tris-aryloxide ligand for high-performance oxygen sensors

Dalton transactions : an international journal of inorganic chemistry, 2017-07, Vol.46 (28), p.9126-913

2017

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Molecular mechanisms of avian immunoglobulin gene diversification and prospect for industrial applications

TET3 dioxygenase modulates gene conversion at the avian immunoglobulin variable region via demethylation of non‐CpG sites in pseudogene templates

Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line

B Cell-Based Seamless Engineering of Antibody Fc Domains

Fast-tracking antibody maturation using a B cell-based display system

Rapid generation of specific antibodies by enhanced homologous recombination

Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion

Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40

Fabrication of a Novel Photoelectric Conversion Device Consisting of a Poly-3-dodecylthiophene Film and C60 Fullerene–Ethylenediamine Nanoparticles

A DNA unwinding factor involved in DNA replication in cell-free extracts of Xenopus eggs

Modulation of Immunoglobulin Gene Conversion in Chicken DT40 by Enhancing Histone Acetylation, and its Application to Antibody Engineering

An ex vivo method for rapid generation of monoclonal antibodies (ADLib system)

Drug discovery using new genome reorganization and genome synthesis techniques

ADLib System for Rapid and Flexible Design of Monoclonal Antibodies

ADLib System for Rapid and Flexible Design of Monoclonal Antibodies

p97 ATPase, an ATPase involved in membrane fusion, interacts with DNA unwinding factor (DUF) that functions in DNA replication

Incorporation of DUF/FACT into chromatin enhances the accessibility of nucleosomal DNA

Fast-tracking antibody maturation using a B cell-based display system

ADLibシステムを用いたモノクローナル抗体の迅速作製

ADLib System for Rapid and Flexible Design of Monoclonal Antibodies

Simple Fabrication of [C60]Fullerene Assemblies by using Linker Molecules and their Photoelectrochemical Application

Control of Lanthanide Coordination Environment: Synthesis, Structure, and Oxygen-Sensitive Luminescence Properties of an Eight-Coordinate Tb(III) Complex

An oxygen-sensitive luminescent Dy(iii) complex

Value of 3-Dimensional Speckle Tracking Echocardiography in the Prediction of Microvascular Obstruction and Left Ventricular Remodeling in Patients With ST-Elevation Myocardial Infarction

Luminescent Tb() and Sm() complexes with a 1,4,7-triazacyclononane-based tris-aryloxide ligand for high-performance oxygen sensors

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