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Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles

Molecules (Basel, Switzerland), 2020-09, Vol.25 (17), p.3999

2020

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Tryptophan Substitution in CJ-15,208 ( cyclo [Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of Extinguished Cocaine-Conditioned Place Preference

Pharmaceuticals (Basel, Switzerland), 2023-08, Vol.16 (9), p.1218

2023

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Pharmacokinetic and Toxicodynamic Characterization of a Novel Doxorubicin Derivative

Pharmaceutics, 2017-09, Vol.9 (3), p.35

2017

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Photorelease of phosphates: Mild methods for protecting phosphate derivatives

Beilstein journal of organic chemistry, 2014-08, Vol.10 (1), p.2038-2054

2014

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In Situ Electrochemical Monitoring of Caged Compound Photochemistry: An Internal Actinometer for Substrate Release

Analytical chemistry (Washington), 2021-02, Vol.93 (5), p.2776-2784

2021

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Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist [D-Trp]CJ-15,208 in plasma and application to an initial pharmacokinetic study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-08, Vol.1028, p.11-15

2016

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Rational Drug Design of Targeted and Enzyme-Cleavable Vitamin E Analogs as a Neoadjuvant to Chemotherapy: In Vitro and In Vivo Evaluation on Reduction of the Cardiotoxicity Side Effect of Doxorubicin

ACS pharmacology & translational science, 2023-03, Vol.6 (3), p.372-386

2023

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Formation of platinum (II) as a six member ring for sustained polymeric delivery

European journal of medicinal chemistry, 2017-08, Vol.136, p.452-456

2017

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Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth

Cancer biology & therapy, 2017-08, Vol.18 (8), p.571-583

2017

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The macrocyclic tetrapeptide [D‐Trp]CJ‐15,208 produces short‐acting κ opioid receptor antagonism in the CNS after oral administration

British journal of pharmacology, 2013-05, Vol.169 (2), p.426-436

2013

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The Macrocyclic Peptide Natural Product CJ-15,208 Is Orally Active and Prevents Reinstatement of Extinguished Cocaine-Seeking Behavior

Journal of natural products (Washington, D.C.), 2013-03, Vol.76 (3), p.433-438

2013

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2-Diazo-1-(4-hydroxyphenyl)ethanone: a versatile photochemical and synthetic reagent

Photochemical & photobiological sciences, 2014-01, Vol.13 (2), p.324-341

2014

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Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative

Drug delivery and translational research, 2017-08, Vol.7 (4), p.582-597

2017

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Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ-15,208

ChemMedChem, 2011-09, Vol.6 (9), p.1739-1745

2011

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Correction to: Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative

Drug delivery and translational research, 2018-10, Vol.8 (5), p.1592-1592

2018

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Gas-Phase Fragmentation of Deprotonated p-Hydroxyphenacyl Derivatives

Journal of organic chemistry, 2011-04, Vol.76 (7), p.2180-2186

2011

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2-Diazo-1-(4-hydroxyphenyl)ethanone: A Versatile Photochemical and Synthetic Reagenta

Photochemical & photobiological sciences, 2014-02, Vol.13 (2), p.324-341

2014

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2-Diazo-1-(4-hydroxyphenyl)ethanone: a versatile photochemical and synthetic reagentThis article is dedicated to the memory of Professor Nicholas J. Turro (1938-2012), one of the giants of physical-organic photochemistry upon whose shoulders many of us stood.Electronic supplementary information (ESI) available. See DOI: 10.1039/c3pp50305d

2014-01

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The Macrocyclic Peptide Natural Product CJ-15,208 is Orally Active and Prevents Reinstatement of Extinguished Cocaine Seeking Behavior1

Journal of natural products (Washington, D.C.), 2013-01, Vol.76 (3)

2013

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The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting [kappa] opioid receptor antagonism in the CNS after oral administration

British journal of pharmacology, 2013-05, Vol.169 (2), p.426-436

2013

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I. A crossover mechanistic investigation of the Wolff vs. photo-Favorskii Rearrangement of Diazo-p-Hydroxyacetophenone: Methoxy substituent effects on p-Hydroxyphenacyl cage II. Exploratory studies of hydroxyquinoline-based phototriggers

Senadheera, Sanjeewa N

2010

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Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles

Tryptophan Substitution in CJ-15,208 ( cyclo [Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of Extinguished Cocaine-Conditioned Place Preference

Pharmacokinetic and Toxicodynamic Characterization of a Novel Doxorubicin Derivative

Photorelease of phosphates: Mild methods for protecting phosphate derivatives

In Situ Electrochemical Monitoring of Caged Compound Photochemistry: An Internal Actinometer for Substrate Release

Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist [D-Trp]CJ-15,208 in plasma and application to an initial pharmacokinetic study

Rational Drug Design of Targeted and Enzyme-Cleavable Vitamin E Analogs as a Neoadjuvant to Chemotherapy: In Vitro and In Vivo Evaluation on Reduction of the Cardiotoxicity Side Effect of Doxorubicin

Formation of platinum (II) as a six member ring for sustained polymeric delivery

Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth

The macrocyclic tetrapeptide [D‐Trp]CJ‐15,208 produces short‐acting κ opioid receptor antagonism in the CNS after oral administration

The Macrocyclic Peptide Natural Product CJ-15,208 Is Orally Active and Prevents Reinstatement of Extinguished Cocaine-Seeking Behavior

2-Diazo-1-(4-hydroxyphenyl)ethanone: a versatile photochemical and synthetic reagent

Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative

Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ-15,208

Correction to: Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative

Gas-Phase Fragmentation of Deprotonated p-Hydroxyphenacyl Derivatives

2-Diazo-1-(4-hydroxyphenyl)ethanone: A Versatile Photochemical and Synthetic Reagenta

The Macrocyclic Peptide Natural Product CJ-15,208 is Orally Active and Prevents Reinstatement of Extinguished Cocaine Seeking Behavior1

The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting [kappa] opioid receptor antagonism in the CNS after oral administration

I. A crossover mechanistic investigation of the Wolff vs. photo-Favorskii Rearrangement of Diazo-p-Hydroxyacetophenone: Methoxy substituent effects on p-Hydroxyphenacyl cage II. Exploratory studies of hydroxyquinoline-based phototriggers

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