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Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

PLoS pathogens, 2020-11, Vol.16 (11), p.e1009034-e1009034

2020

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Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Immunity (Cambridge, Mass.), 2016-05, Vol.44 (5), p.1151-1161

2016

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Tyrosine phosphorylation in Toll-like receptor signaling

Cytokine & growth factor reviews, 2014-10, Vol.25 (5), p.533-541

2014

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Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009950-e1009950

2021

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dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Journal of interferon & cytokine research, 2014-06, Vol.34 (6), p.427

2014

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Interferons and viral infections

BioFactors (Oxford), 2009-01, Vol.35 (1), p.14-20

2009

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Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Nature communications, 2020-02, Vol.11 (1), p.900-15, Article 900

2020

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Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

PLoS pathogens, 2012-05, Vol.8 (5), p.e1002712-e1002712

2012

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RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Protein & Cell, 2017-03, Vol.8 (3), p.165-168

2017

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Interferons at age 50: past, current and future impact on biomedicine

Nature reviews. Drug discovery, 2007-12, Vol.6 (12), p.975-990

2007

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p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.E89-E98

2013

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A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006877

2018

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2′- O methylation of the viral mRNA cap evades host restriction by IFIT family members

Nature (London), 2010-11, Vol.468 (7322), p.452-456

2010

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Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007674-e1007674

2019

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STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection

Cell host & microbe, 2016-09, Vol.20 (3), p.329-341

2016

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IRF3-mediated pathogenicity in a murine model of human hepatitis A

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009960-e1009960

2021

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Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

The EMBO journal, 2008-12, Vol.27 (24), p.3311-3321

2008

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A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain

Journal of Virology, 2013-08, Vol.87 (15), p.8363-8371

2013

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2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

PLoS pathogens, 2012, Vol.8 (5), p.e1002698-e1002698

2012

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VIRUSES AND INTERFERONS

Annual review of microbiology, 2001-01, Vol.55 (1), p.255-281

Sen, Ganes C

2001

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Interferon-induced Ifit proteins: their role in viral pathogenesis

Journal of virology, 2015-03, Vol.89 (5), p.2462-2468

2015

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Viral apoptosis is induced by IRF-3-mediated activation of Bax

The EMBO journal, 2010-05, Vol.29 (10), p.1762-1773

2010

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The IRF-3/Bax-Mediated Apoptotic Pathway, Activated by Viral Cytoplasmic RNA and DNA, Inhibits Virus Replication

Journal of Virology, 2011-04, Vol.85 (8), p.3708-3716

2011

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STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk

mBio, 2021-12, Vol.12 (6), p.e0322821-e0322821

2021

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Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus

Journal of virology, 2014-09, Vol.88 (18), p.10303-10311

2014

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Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Tyrosine phosphorylation in Toll-like receptor signaling

Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis

dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Interferons and viral infections

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Interferons at age 50: past, current and future impact on biomedicine

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

2′- O methylation of the viral mRNA cap evades host restriction by IFIT family members

Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection

IRF3-mediated pathogenicity in a murine model of human hepatitis A

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

VIRUSES AND INTERFERONS

Interferon-induced Ifit proteins: their role in viral pathogenesis

Viral apoptosis is induced by IRF-3-mediated activation of Bax

The IRF-3/Bax-Mediated Apoptotic Pathway, Activated by Viral Cytoplasmic RNA and DNA, Inhibits Virus Replication

STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk

Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus

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