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SEA-TROSY (Solvent Exposed Amides with TROSY): A Method to Resolve the Problem of Spectral Overlap in Very Large Proteins

Journal of the American Chemical Society, 2001-05, Vol.123 (19), p.4633-4634

2001

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Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 cells

Cancer research (Chicago, Ill.), 1991-11, Vol.51 (22), p.6199-6201

1991

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AmineDB: Large scale docking of amines with CYP2D6 and scoring for druglike properties-towards defining the scope of the chemical defense against foreign amines in humans

Xenobiotica, 2007-03, Vol.37 (3), p.221-245

2007

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Geometric relationship between the nicotinamide and isoalloxazine rings in NADPH-cytochrome P-450 oxidoreductase: implications for the classification of evolutionarily and functionally related flavoproteins

Biochemistry (Easton), 1992-04, Vol.31 (13), p.3391-3398

1992

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Phosphorylated thiosugars : synthesis, properties, and reactivity in enzymatic reactions

Biochemistry (Easton), 1991-05, Vol.30 (20), p.4970-4977

1991

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Mechanistic Studies on the Reductive Half-reaction of NADPH-Cytochrome P450 Oxidoreductase

The Journal of biological chemistry, 1999-02, Vol.274 (9), p.5391-5398

1999

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Phosphorylated aminosugars : synthesis, properties, and reactivity in enzymatic reactions

Biochemistry (Easton), 1991-05, Vol.30 (20), p.4978-4984

1991

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High-resolution solution structure of the retinoid X receptor DNA-binding domain

Journal of molecular biology, 1998-08, Vol.281 (2), p.271-284

1998

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Object-oriented approach to drug design enabled by NMR SOLVE: First real-time structural tool for characterizing protein-ligand interactions

Journal of cellular biochemistry, 2001, Vol.84 (S37), p.99-105

2001

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Antibody Affinities and Relative Titers in Polyclonal Populations: Surface Plasmon Resonance Analysis of anti-DNA Antibodies

Archives of biochemistry and biophysics, 1999-12, Vol.372 (1), p.62-68

1999

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Application of fluorescence polarization to the steady-state enzyme kinetic analysis of calpain II

FEBS letters, 1999-01, Vol.443 (1), p.17-19

1999

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Effect of Ionic Strength on the Kinetic Mechanism and Relative Rate Limitation of Steps in the Model NADPH-Cytochrome P450 Oxidoreductase Reaction with Cytochrome c

Biochemistry (Easton), 1995-10, Vol.34 (39), p.12768-12774

1995

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Nmr in drug discovery

Nature reviews. Drug discovery, 2002-03, Vol.1 (3), p.211-219

2002

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NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein

The Journal of biological chemistry, 1997-07, Vol.272 (29), p.18038-18043

1997

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Structural Characterization and Optimization of Antibody-Selected Phage Library Mimotopes of an Antigen Associated with Autoimmune Recurrent Thrombosis

Biochemistry (Easton), 1998-11, Vol.37 (46), p.16069-16081

1998

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Enzyme-substrate binding interactions of NADPH-cytochrome P-450 oxidoreductase characterized with pH and alternate substrate/inhibitor studies

Biochemistry (Easton), 1993-11, Vol.32 (43), p.11539-11547

1993

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Kinetic Mechanism for the Model Reaction of NADPH-Cytochrome P450 Oxidoreductase with Cytochrome c

Biochemistry (Easton), 1994-10, Vol.33 (40), p.12012-12021

1994

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Interaction with arginine 597 of NADPH-cytochrome P-450 oxidoreductase is a primary source of the uniform binding energy used to discriminate between NADPH and NADH

Biochemistry (Easton), 1993-11, Vol.32 (43), p.11548-11558

1993

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NMR in the acceleration of drug discovery

Current opinion in drug discovery & development, 2001-07, Vol.4 (4), p.479

2001

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Phosphorylated aminosugars; synthesis, properties, and reactivity in enzymic reactions

Biochemistry (Easton), 1991-05, Vol.30 (20), p.4978-4984

1991

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NMR-based structural characterization of large protein-ligand interactions

Journal of biomolecular NMR, 2002-02, Vol.22 (2), p.165-173

2002

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Phosphorylated thiosugars: synthesis, properties, and reactivity in enzymic reactions

Biochemistry (Easton), 1991-05, Vol.30 (20), p.4970-4977

1991

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Cofactor fingerprinting with STD NMR to characterize proteins of unknown function: identification of a rare cCMP cofactor preference

FEBS letters, 2005-01, Vol.579 (3), p.661-666

2005

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Chemical Proteomic Tool for Ligand Mapping of CYP Antitargets: An NMR-Compatible 3D QSAR Descriptor in the Heme-Based Coordinate System

Journal of Chemical Information and Computer Sciences, 2004-07, Vol.44 (4), p.1456-1465

2004

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NMR assignments and secondary structure of the retinoid X receptor alpha DNA-binding domain. Evidence for the novel C-terminal helix

European journal of biochemistry, 1994-09, Vol.224 (2), p.639-650

1994

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SEA-TROSY (Solvent Exposed Amides with TROSY): A Method to Resolve the Problem of Spectral Overlap in Very Large Proteins

Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 cells

AmineDB: Large scale docking of amines with CYP2D6 and scoring for druglike properties-towards defining the scope of the chemical defense against foreign amines in humans

Geometric relationship between the nicotinamide and isoalloxazine rings in NADPH-cytochrome P-450 oxidoreductase: implications for the classification of evolutionarily and functionally related flavoproteins

Phosphorylated thiosugars : synthesis, properties, and reactivity in enzymatic reactions

Mechanistic Studies on the Reductive Half-reaction of NADPH-Cytochrome P450 Oxidoreductase

Phosphorylated aminosugars : synthesis, properties, and reactivity in enzymatic reactions

High-resolution solution structure of the retinoid X receptor DNA-binding domain

Object-oriented approach to drug design enabled by NMR SOLVE: First real-time structural tool for characterizing protein-ligand interactions

Antibody Affinities and Relative Titers in Polyclonal Populations: Surface Plasmon Resonance Analysis of anti-DNA Antibodies

Application of fluorescence polarization to the steady-state enzyme kinetic analysis of calpain II

Effect of Ionic Strength on the Kinetic Mechanism and Relative Rate Limitation of Steps in the Model NADPH-Cytochrome P450 Oxidoreductase Reaction with Cytochrome c

Nmr in drug discovery

NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein

Structural Characterization and Optimization of Antibody-Selected Phage Library Mimotopes of an Antigen Associated with Autoimmune Recurrent Thrombosis

Enzyme-substrate binding interactions of NADPH-cytochrome P-450 oxidoreductase characterized with pH and alternate substrate/inhibitor studies

Kinetic Mechanism for the Model Reaction of NADPH-Cytochrome P450 Oxidoreductase with Cytochrome c

Interaction with arginine 597 of NADPH-cytochrome P-450 oxidoreductase is a primary source of the uniform binding energy used to discriminate between NADPH and NADH

NMR in the acceleration of drug discovery

Phosphorylated aminosugars; synthesis, properties, and reactivity in enzymic reactions

NMR-based structural characterization of large protein-ligand interactions

Phosphorylated thiosugars: synthesis, properties, and reactivity in enzymic reactions

Cofactor fingerprinting with STD NMR to characterize proteins of unknown function: identification of a rare cCMP cofactor preference

Chemical Proteomic Tool for Ligand Mapping of CYP Antitargets: An NMR-Compatible 3D QSAR Descriptor in the Heme-Based Coordinate System

NMR assignments and secondary structure of the retinoid X receptor alpha DNA-binding domain. Evidence for the novel C-terminal helix

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