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1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226

European journal of medicinal chemistry, 2020-03, Vol.189, p.112062-112062, Article 112062

2020

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Synthesis and anticancer activity of new dihydropyrimidinone derivatives

European journal of medicinal chemistry, 2018-08, Vol.156, p.304-315

2018

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Efficient Chiral N-Heterocyclic Carbene/Copper(I)-Catalyzed Asymmetric Allylic Arylation with Aryl Grignard Reagents

Angewandte Chemie (International ed.), 2009-11, Vol.48 (46), p.8733-8735

2009

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Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C‑Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rational

Journal of organic chemistry, 2014-04, Vol.79 (8), p.3414-3426

2014

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Design, synthesis and docking study of novel picolinamide derivatives as anticancer agents and VEGFR-2 inhibitors

European journal of medicinal chemistry, 2019-04, Vol.168, p.315-329

2019

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Enantioselective 1,3‐Dipolar Cycloaddition Reactions of C‐Carboxy Ketonitrones and Enals with MacMillan Catalysts: Evidence of a Nonconcerted Mechanism

European journal of organic chemistry, 2017-12, Vol.2017 (45), p.6763-6774

2017

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Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives

Bioorganic & medicinal chemistry, 2019-10, Vol.27 (19), p.115026-115026, Article 115026

2019

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Dihydrofolate reductase inhibition effect of 5-substituted pyrido[2,3-d]pyrimidines: Synthesis, antitumor activity and molecular modeling study

Bioorganic chemistry, 2019-09, Vol.90, p.103076-103076, Article 103076

2019

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Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.1426-1438

2019

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Total Synthesis of Eleuthoside A; Application of Rh-Catalyzed Intramolecular Cyclization of Diazonaphthoquinone

Synlett, 2018-03, Vol.29 (4), p.457-462

2018

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Nitroimidazole derivatives potentiated against tumor hypoxia: Design, synthesis, antitumor activity, molecular docking study, and QSAR study

Drug development research, 2024-02, Vol.85 (1), p.e22126-n/a

2024

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Exploration of antiproliferative potential of modified triazole–benzohydrazone scaffold: Multitarget approach

Archiv der Pharmazie (Weinheim), 2024-02, Vol.357 (2), p.e2300383-n/a

2024

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Synthesis and Biological Evaluation of 2,4-Diaminoquinazolines as Potential Antitumor Agents

Journal of chemistry, 2022-10, Vol.2022, p.1-6

2022

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Chiral N-Heterocyclic Carbene−Copper(I)-Catalyzed Asymmetric Allylic Arylation of Aliphatic Allylic Bromides: Steric and Electronic Effects on γ-Selectivity

Journal of organic chemistry, 2011-03, Vol.76 (5), p.1398-1408

2011

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Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study

ACS omega, 2023-07, Vol.8 (29), p.26012-26034

2023

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Identification of 1 H -pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2019-12, Vol.34 (1), p.1426-1438

2019

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Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity

Bioorganic chemistry, 2020-10, Vol.103, p.104148-104148, Article 104148

2020

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Insights into modulating the monastrol scaffold: Development of new pyrimidinones as Eg5 inhibitors with anticancer activity

Archiv der Pharmazie (Weinheim), 2022-10, Vol.355 (10), p.e2200029-n/a

2022

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Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.1487-1498

2021

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1,3-Dipolar cycloaddition of vinyloxy quinolines with α-alkoxy carbonyl aldonitrones or cyclic surrogates: A comparative study for an asymmetric access to trans 4-quinolinoxy oxaprolines

Tetrahedron, 2019-01, Vol.75 (3), p.429-440

2019

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Synthesis, Antitumor Activity, and In Silico Drug Design of New Thieno[2,3‑d]Pyrimidine-4-One Derivatives as Nonclassical Lipophilic Dihydrofolate Reductase Inhibitors

ACS omega, 2022-12, Vol.7 (49), p.45455-45468

2022

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Correction to “Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C‑Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rationale”

Journal of organic chemistry, 2015-11, Vol.80 (21), p.11226-11226

2015

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Stereoselective total synthesis of the E-isomer of putative lucentamycin A

Tetrahedron letters, 2012-10, Vol.53 (44), p.5895-5898

2012

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Effect of Diabetes Duration on Proliferative Disease Regression after Panretinal Photocoagulation Using a Conventional Laser Versus Pattern Scan Multispot Laser

The Egyptian journal of hospital medicine, 2020-01, Vol.78 (1), p.123-127

2020

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Copper-catalyzed asymmetric allylic substitution with aryl and ethyl Grignard reagents

Chemical communications (Cambridge, England), 2008-01 (41), p.5140-5142

2008

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1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226

Synthesis and anticancer activity of new dihydropyrimidinone derivatives

Efficient Chiral N-Heterocyclic Carbene/Copper(I)-Catalyzed Asymmetric Allylic Arylation with Aryl Grignard Reagents

Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C‑Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rational

Design, synthesis and docking study of novel picolinamide derivatives as anticancer agents and VEGFR-2 inhibitors

Enantioselective 1,3‐Dipolar Cycloaddition Reactions of C‐Carboxy Ketonitrones and Enals with MacMillan Catalysts: Evidence of a Nonconcerted Mechanism

Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives

Dihydrofolate reductase inhibition effect of 5-substituted pyrido[2,3-d]pyrimidines: Synthesis, antitumor activity and molecular modeling study

Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors

Total Synthesis of Eleuthoside A; Application of Rh-Catalyzed Intramolecular Cyclization of Diazonaphthoquinone

Nitroimidazole derivatives potentiated against tumor hypoxia: Design, synthesis, antitumor activity, molecular docking study, and QSAR study

Exploration of antiproliferative potential of modified triazole–benzohydrazone scaffold: Multitarget approach

Synthesis and Biological Evaluation of 2,4-Diaminoquinazolines as Potential Antitumor Agents

Chiral N-Heterocyclic Carbene−Copper(I)-Catalyzed Asymmetric Allylic Arylation of Aliphatic Allylic Bromides: Steric and Electronic Effects on γ-Selectivity

Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study

Identification of 1 H -pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors

Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity

Insights into modulating the monastrol scaffold: Development of new pyrimidinones as Eg5 inhibitors with anticancer activity

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study

1,3-Dipolar cycloaddition of vinyloxy quinolines with α-alkoxy carbonyl aldonitrones or cyclic surrogates: A comparative study for an asymmetric access to trans 4-quinolinoxy oxaprolines

Synthesis, Antitumor Activity, and In Silico Drug Design of New Thieno[2,3‑d]Pyrimidine-4-One Derivatives as Nonclassical Lipophilic Dihydrofolate Reductase Inhibitors

Correction to “Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C‑Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rationale”

Stereoselective total synthesis of the E-isomer of putative lucentamycin A

Effect of Diabetes Duration on Proliferative Disease Regression after Panretinal Photocoagulation Using a Conventional Laser Versus Pattern Scan Multispot Laser

Copper-catalyzed asymmetric allylic substitution with aryl and ethyl Grignard reagents

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