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An Expedient Synthesis of Flexible Nucleosides through Enzymatic Glycosylation of Proximal and Distal Fleximer Bases

Chembiochem : a European journal of chemical biology, 2020-05, Vol.21 (10), p.1412-1417

2020

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Recent advances in synthetic approaches for medicinal chemistry of C-nucleosides

Beilstein journal of organic chemistry, 2018-04, Vol.14 (1), p.772-785

2018

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The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold

Antiviral research, 2018-06, Vol.154, p.66-86

2018

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The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold

Antiviral research, 2019-02, Vol.162, p.5-21

2019

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Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro

Bioorganic & medicinal chemistry, 2020-11, Vol.28 (22), p.115713-115713, Article 115713

2020

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Comparison of the Old and New - Novel Mechanisms of Action for Anti-coronavirus Nucleoside Analogues

Chimia, 2022-05, Vol.76 (5), p.409

2022

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Discovery, Design, Synthesis, and Application of Nucleoside/Nucleotides

Molecules (Basel, Switzerland), 2020-03, Vol.25 (7), p.1526

Seley-Radtke, Katherine

2020

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Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides

Chemistry : a European journal, 2015-09, Vol.21 (38), p.13401-13419

2015

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Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity

Molecules (Basel, Switzerland), 2019-09, Vol.24 (17), p.3184

2019

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Anticancer Properties of Halogenated Pyrrolo[3,2‐d]pyrimidines with Decreased Toxicity via N5 Substitution

ChemMedChem, 2018-01, Vol.13 (2), p.178-185

2018

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Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2- d ]pyrimidines as Potential Anti-Cancer Therapeutics

Molecules (Basel, Switzerland), 2019-07, Vol.24 (14), p.2656

2019

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Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4151-4157

2013

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Design and synthesis of a series of truncated neplanocin fleximers

Molecules (Basel, Switzerland), 2014-12, Vol.19 (12), p.21200-21214

2014

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Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

Molecules (Basel, Switzerland), 2019-09, Vol.24 (19), p.3433

2019

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Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses

Antiviral chemistry & chemotherapy, 2018, Vol.26, p.2040206618761299

2018

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5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis

Chemical biology & drug design, 2015-12, Vol.86 (6), p.1387-1396

2015

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Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines

Bioorganic & medicinal chemistry, 2015-08, Vol.23 (15), p.4354-4363

2015

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Thiophene-expanded guanosine analogues of Gemcitabine

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (19), p.4274-4276

2015

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Proximal fleximer analogues of 2′-deoxy-2′-fluoro-2′-methyl purine nucleos(t)ides: Synthesis and preliminary pharmacokinetic and antiviral evaluation

Bioorganic & medicinal chemistry, 2024-10, Vol.112, p.117898, Article 117898

2024

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N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase

Bioorganic & medicinal chemistry, 2013-03, Vol.21 (5), p.1150-1158

2013

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Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity

Bioorganic & medicinal chemistry letters, 2015-08, Vol.25 (15), p.2923-2926

2015

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Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP

Molecules (Basel, Switzerland), 2023-01, Vol.28 (3), p.928

2023

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Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1

Bioorganic & medicinal chemistry, 2019-07, Vol.27 (13), p.2883-2892

2019

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Identification of a macrocyclic compound targeting the lassa virus polymerase

Antiviral research, 2024-08, Vol.228, p.105923, Article 105923

2024

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Flex-nucleoside analogues – Novel therapeutics against filoviruses

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2800-2802

2017

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An Expedient Synthesis of Flexible Nucleosides through Enzymatic Glycosylation of Proximal and Distal Fleximer Bases

Recent advances in synthetic approaches for medicinal chemistry of C-nucleosides

The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold

The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold

Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro

Comparison of the Old and New - Novel Mechanisms of Action for Anti-coronavirus Nucleoside Analogues

Discovery, Design, Synthesis, and Application of Nucleoside/Nucleotides

Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides

Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity

Anticancer Properties of Halogenated Pyrrolo[3,2‐d]pyrimidines with Decreased Toxicity via N5 Substitution

Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2- d ]pyrimidines as Potential Anti-Cancer Therapeutics

Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof

Design and synthesis of a series of truncated neplanocin fleximers

Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses

5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis

Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines

Thiophene-expanded guanosine analogues of Gemcitabine

Proximal fleximer analogues of 2′-deoxy-2′-fluoro-2′-methyl purine nucleos(t)ides: Synthesis and preliminary pharmacokinetic and antiviral evaluation

N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase

Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity

Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP

Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1

Identification of a macrocyclic compound targeting the lassa virus polymerase

Flex-nucleoside analogues – Novel therapeutics against filoviruses

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