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Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity

PLoS genetics, 2016-03, Vol.12 (3), p.e1005917

2016

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Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

BMC neuroscience, 2018-07, Vol.19 (1), p.46-46, Article 46

2018

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Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila

PLoS genetics, 2018-01, Vol.14 (1), p.e1007196-e1007196

2018

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Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1

PLoS genetics, 2012-08, Vol.8 (8), p.e1002918-e1002918

2012

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EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila

Developmental cell, 2017-06, Vol.41 (6), p.652-664.e5

2017

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Inulooligosaccharides in Atractylodis lanceae rhizoma and Atractylodis rhizoma of hochuekkito formula are essential for regulation of the pulmonary immune system of immuno‐compromised mice

Traditional & Kampo medicine, 2020-08, Vol.7 (2), p.96-107

2020

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Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration

iScience, 2023-02, Vol.26 (2), p.105968-105968, Article 105968

2023

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Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models

Genome medicine, 2018-03, Vol.10 (1), p.26-26, Article 26

2018

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Tomoeones A–H, cytotoxic phloroglucinol derivatives from Hypericum ascyron

Phytochemistry (Oxford), 2008-08, Vol.69 (11), p.2225-2230

2008

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The Chinese Prescription Wen-Pi-Tang Extract Delays Disease Onset in Amyotrophic Lateral Sclerosis Model Mice While Attenuating the Activation of Glial Cells in the Spinal Cord

Biological and Pharmaceutical Bulletin, 2009/03/01, Vol.32(3), pp.382-388

2009

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Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito, and its active ingredients

Journal of natural medicines, 2013-07, Vol.67 (3), p.626-635

2013

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Polysaccharide-Containing Macromolecules in a Kampo (Traditional Japanese Herbal) Medicine, Hochuekkito: Dual Active Ingredients for Modulation of Immune Functions on Intestinal Peyer’s Patches and Epithelial cells

Evidence-based complementary and alternative medicine, 2011-01, Vol.2011, p.492691-13

2011

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Anti‐inflammatory effect of hospital‐grade hochuekkito extract, a traditional Japanese herbal medicine, on methotrexate‐induced intestinal mucositis in mice

Traditional & Kampo medicine, 2015-09, Vol.2 (2), p.81-88

2015

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Effect on both aglycone and sugar moiety towards Phase II metabolism of anthocyanins

Food chemistry, 2008-09, Vol.110 (2), p.493-500

2008

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Disruption of a RAC1-centred network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegeneration

Human molecular genetics, 2020-03, Vol.29 (5), p.817-833

2020

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Alzheimer’s disease biomarker‐related phospho‐tau 181 signals localize to demyelinated axons of parvalbumin‐positive GABAergic interneurons in App knock‐in mouse

Alzheimer's & dementia, 2023-12, Vol.19 (S13)

2023

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Reduced density of serotonergic axons without prominent neuron loss or tau pathology in the dorsal raphe nucleus in App knock‐in mouse models of amyloid‐β pathology

Alzheimer's & dementia, 2023-12, Vol.19 (S13)

2023

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Reduced density of cholinergic fibers in App knock‐in mouse models of Aβ amyloidosis

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Alzheimer's Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pathology

Journal of Alzheimer's disease, 2023-01, Vol.93 (3), p.1065

2023

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Antioxidant effect of Wen-Pi-Tang and its component crude drugs on oxidative stress

The American journal of Chinese medicine (1979), 2007, Vol.35 (1), p.127

2007

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Localization of AD biomarker phospho‐tau proteins in the brains of an App knock‐in mouse model of Aβ amyloidosis

Alzheimer's & dementia, 2021-12, Vol.17, p.e057738-n/a

2021

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P4‐472: A NOVEL DROSOPHILA MODEL OF ALZHEIMER'S DISEASE

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_29), p.P1492-P1492

2019

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A NOVEL DROSOPHILA MODEL OF ALZHEIMER’S DISEASE

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P1492-P1492

2019

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A Drosophila ortholog of Toll‐like receptors modulates c‐Jun N‐terminal kinase signaling and protects against tau‐mediated neurodegeneration independent of innate immune response

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila

Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1

EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila

Inulooligosaccharides in Atractylodis lanceae rhizoma and Atractylodis rhizoma of hochuekkito formula are essential for regulation of the pulmonary immune system of immuno‐compromised mice

Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration

Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models

Tomoeones A–H, cytotoxic phloroglucinol derivatives from Hypericum ascyron

The Chinese Prescription Wen-Pi-Tang Extract Delays Disease Onset in Amyotrophic Lateral Sclerosis Model Mice While Attenuating the Activation of Glial Cells in the Spinal Cord

Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito, and its active ingredients

Polysaccharide-Containing Macromolecules in a Kampo (Traditional Japanese Herbal) Medicine, Hochuekkito: Dual Active Ingredients for Modulation of Immune Functions on Intestinal Peyer’s Patches and Epithelial cells

Anti‐inflammatory effect of hospital‐grade hochuekkito extract, a traditional Japanese herbal medicine, on methotrexate‐induced intestinal mucositis in mice

Effect on both aglycone and sugar moiety towards Phase II metabolism of anthocyanins

Disruption of a RAC1-centred network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegeneration

Alzheimer’s disease biomarker‐related phospho‐tau 181 signals localize to demyelinated axons of parvalbumin‐positive GABAergic interneurons in App knock‐in mouse

Reduced density of serotonergic axons without prominent neuron loss or tau pathology in the dorsal raphe nucleus in App knock‐in mouse models of amyloid‐β pathology

Reduced density of cholinergic fibers in App knock‐in mouse models of Aβ amyloidosis

Alzheimer's Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pathology

Antioxidant effect of Wen-Pi-Tang and its component crude drugs on oxidative stress

Localization of AD biomarker phospho‐tau proteins in the brains of an App knock‐in mouse model of Aβ amyloidosis

P4‐472: A NOVEL DROSOPHILA MODEL OF ALZHEIMER'S DISEASE

A NOVEL DROSOPHILA MODEL OF ALZHEIMER’S DISEASE

A Drosophila ortholog of Toll‐like receptors modulates c‐Jun N‐terminal kinase signaling and protects against tau‐mediated neurodegeneration independent of innate immune response

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