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Measurement of biological washout rates depending on tumor vascular status in 15O in-beam rat-PET

Physics in medicine & biology, 2022-06, Vol.67 (12)

2022

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Detection of Alzheimer’s disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein

Journal of cerebral blood flow and metabolism, 2021-08, Vol.41 (8), p.2076-2089

2021

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Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model

The Journal of neuroscience, 2020-04, Vol.40 (17), p.3491-3501

2020

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DOCK–PET: database of CNS kinetic parameters in the healthy human brain for existing PET tracers

Annals of nuclear medicine, 2024-08, Vol.38 (8), p.666-672

2024

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PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflammation and a rhesus monkey

Journal of cerebral blood flow and metabolism, 2021-09, Vol.41 (9), p.2410-2422

2021

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A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains

The EMBO journal, 2021-11, Vol.40 (22), p.e107757-n/a

2021

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Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain

European journal of nuclear medicine and molecular imaging, 2021-09, Vol.48 (10), p.3101-3112

2021

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Brain 5-HT2A receptor binding and its neural network related to behavioral inhibition system

Brain imaging and behavior, 2022-06, Vol.16 (3), p.1337-1348

2022

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Design, Synthesis, and Evaluation of (4R)‑1-{3-[2‑(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T‑401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2362-2375

2019

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A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model

European journal of nuclear medicine and molecular imaging, 2022-11, Vol.49 (13), p.4298-4311

2022

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An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)

NeuroImage (Orlando, Fla.), 2022-12, Vol.264, p.119763-119763, Article 119763

2022

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Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy

Journal of the neurological sciences, 2023-01, Vol.444, p.120514-120514, Article 120514

2023

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A Machine Learning–Based Approach to Discrimination of Tauopathies Using [18F]PM‐PBB3 PET Images

Movement disorders, 2022-11, Vol.37 (11), p.2236-2246

2022

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A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 7

European journal of nuclear medicine and molecular imaging, 2021-08, Vol.48 (9), p.2846-2855

2021

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Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study

Cerebral cortex (New York, N.Y. 1991), 2020-11, Vol.30 (12), p.6458-6468

2020

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Pharmacokinetic and pharmacodynamic assessment of histamine H3 receptor occupancy by enerisant: a human PET study with a novel H3 binding ligand, [11C]TASP457

European journal of nuclear medicine and molecular imaging, 2022-03, Vol.49 (4), p.1127-1135

2022

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Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism

Scientific reports, 2023-07, Vol.13 (1), p.11655-11655, Article 11655

2023

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Dynamic alterations in the central glutamatergic status following food and glucose intake: in vivo multimodal assessments in humans and animal models

Journal of cerebral blood flow and metabolism, 2021-11, Vol.41 (11), p.2928-2943

2021

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Investigating neural dysfunction with abnormal protein deposition in Alzheimer’s disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography

NeuroImage clinical, 2024, Vol.41, p.103560-103560, Article 103560

2024

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Imaging extra-striatal dopamine D2 receptors in a maternal immune activation rat model

Brain, behavior, & immunity. Health, 2022-07, Vol.22, p.100446-100446, Article 100446

2022

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Activation of Nav1.1 ameliorates tau pathology and brain atrophy in a mouse model of tauopathy

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Prediction of the Clinical SUV Ratio in Amyloid PET Imaging Using a Biomathematic Modeling Approach Toward the Efficient Development of a Radioligand

Journal of Nuclear Medicine, 2017-08, Vol.58 (8), p.1285-1292

2017

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Water Diffusion in the Brain of Chronic Hypoperfusion Model Mice: A Study Considering the Effect of Blood Flow

Magnetic Resonance in Medical Sciences, 2018, Vol.17(4), pp.318-324

2018

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Measurement of biological washout rates depending on tumor vascular status in 15O in-beam rat-PET

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Detection of Alzheimer’s disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein

Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model

DOCK–PET: database of CNS kinetic parameters in the healthy human brain for existing PET tracers

PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflammation and a rhesus monkey

A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains

Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain

Brain 5-HT2A receptor binding and its neural network related to behavioral inhibition system

Visualization of AMPA receptors in living human brain with positron emission tomography

Design, Synthesis, and Evaluation of (4R)‑1-{3-[2‑(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T‑401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase

A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model

An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)

Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy

A Machine Learning–Based Approach to Discrimination of Tauopathies Using [18F]PM‐PBB3 PET Images

A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 7

Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study

Pharmacokinetic and pharmacodynamic assessment of histamine H3 receptor occupancy by enerisant: a human PET study with a novel H3 binding ligand, [11C]TASP457

Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism

Dynamic alterations in the central glutamatergic status following food and glucose intake: in vivo multimodal assessments in humans and animal models

Investigating neural dysfunction with abnormal protein deposition in Alzheimer’s disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography

Imaging extra-striatal dopamine D2 receptors in a maternal immune activation rat model

Activation of Nav1.1 ameliorates tau pathology and brain atrophy in a mouse model of tauopathy

Prediction of the Clinical SUV Ratio in Amyloid PET Imaging Using a Biomathematic Modeling Approach Toward the Efficient Development of a Radioligand

Water Diffusion in the Brain of Chronic Hypoperfusion Model Mice: A Study Considering the Effect of Blood Flow

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