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De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

British journal of cancer, 2009-05, Vol.100 (9), p.1369-1372

2009

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The telomeric PARP, tankyrases, as targets for cancer therapy

British journal of cancer, 2006-02, Vol.94 (3), p.341-345

SEIMIYA, H

2006

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The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma

Oncogene, 2016-07, Vol.35 (27), p.3514-3523

2016

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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells

Oncogene, 2006-03, Vol.25 (13), p.1955-1966

2006

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Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation

Cell death and differentiation, 2012-02, Vol.19 (2), p.321-332

2012

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Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions

Oncogene, 2009-01, Vol.28 (1), p.9-19

2009

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Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer

Oncogene, 2009-03, Vol.28 (11), p.1465-1470

2009

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Involvement of 14-3-3 proteins in nuclear localization of telomerase

The EMBO journal, 2000-06, Vol.19 (11), p.2652-2661

2000

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A phase I study to determine the maximum tolerated dose of trifluridine/tipiracil and oxaliplatin in patients with refractory metastatic colorectal cancer: LUPIN study

Annals of oncology, 2018-10, Vol.29 Suppl 8, p.viii158

2018

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1554P Clinical Impact of ERBB2 copy number and tumor mutation burden (TMB) in patients with HER2- positive advanced gastric cancer treated by nivolumab (N-mab) plus trastuzumab (T-mab) and standard chemotherapy

Annals of oncology, 2023-10, Vol.34, p.S871-S871

2023

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1561P APC mutation (mt.), MYC, and GATA6 amplifications (amp.) were associated with worse survival in HER2-positive advanced gastric cancer patients treated with S-1/capecitabine plus oxaliplatin combined with trastuzumab (T-mab) and nivolumab (N-mab)

Annals of oncology, 2023-10, Vol.34, p.S873-S874

2023

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Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics

Cancer cell, 2005, Vol.7 (1), p.25-37

2005

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The Telomeric Poly(ADP-ribose) Polymerase, Tankyrase 1, Contains Multiple Binding Sites for Telomeric Repeat Binding Factor 1 (TRF1) and a Novel Acceptor, 182-kDa Tankyrase-binding Protein (TAB182)

The Journal of biological chemistry, 2002-04, Vol.277 (16), p.14116-14126

2002

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Functional Involvement of PTP-U2L in Apoptosis Subsequent to Terminal Differentiation of Monoblastoid Leukemia Cells

The Journal of biological chemistry, 1998-08, Vol.273 (33), p.21187-21193

1998

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Pim-1 Negatively Regulates the Activity of PTP-U2S Phosphatase and Influences Terminal Differentiation and Apoptosis of Monoblastoid Leukemia Cells

Archives of biochemistry and biophysics, 2001-06, Vol.390 (1), p.9-18

2001

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Involvement of 14‐3‐3 proteins in nuclear localization of telomerase

The EMBO journal, 2000-06, Vol.19 (11), p.2652-2661

2000

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Protein Tyrosine Phosphatase Receptor-Type O (PTPRO) Exhibits Characteristics of a Candidate Tumor Suppressor in Human Lung Cancer

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (38), p.13844-13849

2004

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Telomerase Inhibition, Telomere Shortening, and Senescence of Cancer Cells by Tea Catechins

Biochemical and biophysical research communications, 1998-08, Vol.249 (2), p.391-396

1998

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Functional Subdomain in the Ankyrin Domain of Tankyrase 1 Required for Poly(ADP-Ribosyl)ation of TRF1 and Telomere Elongation

Molecular and Cellular Biology, 2004-03, Vol.24 (5), p.1944-1955

2004

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c-Jun NH2-terminal Kinase-mediated Activation of Interleukin-1β Converting Enzyme/CED-3-like Protease during Anticancer Drug-induced Apoptosis

The Journal of biological chemistry, 1997-02, Vol.272 (7), p.4631-4636

1997

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FJ5002 : A potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis

Cancer research (Chicago, Ill.), 1999-08, Vol.59 (16), p.4004-4011

1999

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HnRNP A3 binds to and protects mammalian telomeric repeats in vitro

Biochemical and biophysical research communications, 2007-06, Vol.358 (2), p.608-614

2007

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Expression of mutant RPA in human cancer cells causes telomere shortening

Bioscience, biotechnology, and biochemistry, 2010, Vol.74 (2), p.382-385

2010

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ASK1 mediates apoptotic cell death induced by genotoxic stress

Oncogene, 1999-01, Vol.18 (1), p.173-180

1999

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Hypoxia Up-Regulates Telomerase Activity via Mitogen-Activated Protein Kinase Signaling in Human Solid Tumor Cells

Biochemical and biophysical research communications, 1999-07, Vol.260 (2), p.365-370

1999

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De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

The telomeric PARP, tankyrases, as targets for cancer therapy

The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma

G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells

Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation

Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions

Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer

Involvement of 14-3-3 proteins in nuclear localization of telomerase

A phase I study to determine the maximum tolerated dose of trifluridine/tipiracil and oxaliplatin in patients with refractory metastatic colorectal cancer: LUPIN study

1554P Clinical Impact of ERBB2 copy number and tumor mutation burden (TMB) in patients with HER2- positive advanced gastric cancer treated by nivolumab (N-mab) plus trastuzumab (T-mab) and standard chemotherapy

1561P APC mutation (mt.), MYC, and GATA6 amplifications (amp.) were associated with worse survival in HER2-positive advanced gastric cancer patients treated with S-1/capecitabine plus oxaliplatin combined with trastuzumab (T-mab) and nivolumab (N-mab)

Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics

The Telomeric Poly(ADP-ribose) Polymerase, Tankyrase 1, Contains Multiple Binding Sites for Telomeric Repeat Binding Factor 1 (TRF1) and a Novel Acceptor, 182-kDa Tankyrase-binding Protein (TAB182)

Functional Involvement of PTP-U2L in Apoptosis Subsequent to Terminal Differentiation of Monoblastoid Leukemia Cells

Pim-1 Negatively Regulates the Activity of PTP-U2S Phosphatase and Influences Terminal Differentiation and Apoptosis of Monoblastoid Leukemia Cells

Involvement of 14‐3‐3 proteins in nuclear localization of telomerase

Protein Tyrosine Phosphatase Receptor-Type O (PTPRO) Exhibits Characteristics of a Candidate Tumor Suppressor in Human Lung Cancer

Telomerase Inhibition, Telomere Shortening, and Senescence of Cancer Cells by Tea Catechins

Functional Subdomain in the Ankyrin Domain of Tankyrase 1 Required for Poly(ADP-Ribosyl)ation of TRF1 and Telomere Elongation

c-Jun NH2-terminal Kinase-mediated Activation of Interleukin-1β Converting Enzyme/CED-3-like Protease during Anticancer Drug-induced Apoptosis

FJ5002 : A potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis

HnRNP A3 binds to and protects mammalian telomeric repeats in vitro

Expression of mutant RPA in human cancer cells causes telomere shortening

ASK1 mediates apoptotic cell death induced by genotoxic stress

Hypoxia Up-Regulates Telomerase Activity via Mitogen-Activated Protein Kinase Signaling in Human Solid Tumor Cells

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