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Phosphatidylinositol 3-Kinase Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma

Journal of clinical oncology, 2017-12, Vol.35 (35), p.3898-3905

2017

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Exon array analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer

BMC genomics, 2010-11, Vol.11 (1), p.676-676

2010

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Sympathetic restraint of respiratory sinus arrhythmia: implications for vagal-cardiac tone assessment in humans

American journal of physiology. Heart and circulatory physiology, 2001-06, Vol.280 (6), p.H2804-H2814

2001

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Molecular profiles and clinical outcome of stage UICC II colon cancer patients

International journal of colorectal disease, 2011-07, Vol.26 (7), p.847-858

2011

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Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.1731-1741

2019

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Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM

Molecular cancer therapeutics, 2005-01, Vol.4 (1), p.151-170

2005

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Abstract 2606: Biological interpretation of circulating miRNA biomarkers predicting regorafenib clinical benefit in patients with hepatocellular carcinoma (HCC) in the RESORCE trial

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2606-2606

2018

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Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study

European journal of endocrinology, 2023-07, Vol.188 (7), p.578

2023

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Controlled breathing protocols probe human autonomic cardiovascular rhythms

American journal of physiology. Heart and circulatory physiology, 1998-02, Vol.274 (2), p.H709-H718

1998

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Abstract 1798: A detailed comparison between second-generation AR antagonists reveals differences in the overall impact on gene regulation patterns in prostate cancer cells

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1798-1798

2018

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EXTH-38. VELCRIN MOLECULAR GLUES INDUCE CELL DEATH IN GLIOBLASTOMAS WITH HIGH PDE3A AND SLFN12 EXPRESSION

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v232-v233

2023

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Abstract 5036: Correlation of preclinical antitumor activity of regorafenib in CRC-PDX xenografts with gene expression and clinical parameters of the primary tumor

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5036-5036

2017

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Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

The Journal of biological chemistry, 2020-03, Vol.295 (11), p.3431-3446

2020

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Abstract 3599: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of colorectal carcinomas

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3599-3599

2019

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Exploratory biomarker analyses of the single-arm, phase 2 study of regorafenib plus nivolumab in patients (pts) with mismatch repair-proficient (pMMR)/microsatellite stable (MSS) colorectal cancer (CRC)

Journal of clinical oncology, 2022-02, Vol.40 (4_suppl), p.89-89

2022

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Key factors for successful data integration in biomarker research

Nature reviews. Drug discovery, 2016-06, Vol.15 (6), p.369-370

2016

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Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

The Journal of biological chemistry, 2020-11, Vol.295 (48), p.16464-16467

2020

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Abstract 929: Tumor genotyping in the phase III GRID study of regorafenib vs placebo in tyrosine kinase inhibitor (TKI)-refractory GIST: Detection of KIT mutations in circulating tumor DNA comparing digital PCR and massive parallel sequencing

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.929-929

2015

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Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study

EClinicalMedicine, 2023-04, Vol.58, p.101917-101917, Article 101917

2023

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Abstract 3086: Inhibitors of the enzyme dihydroorotate dehydrogenase, overcome the differentiation blockade in acute myeloid leukemia

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3086-3086

2017

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PPARδ Enhances Keratinocyte Proliferation in Psoriasis and Induces Heparin-Binding EGF-Like Growth Factor

Journal of investigative dermatology, 2008-01, Vol.128 (1), p.110-124

2008

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Precompetitive activity to address the biological data needs of drug discovery

Nature reviews. Drug discovery, 2014-02, Vol.13 (2), p.83-84

2014

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Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer

Targeted oncology, 2017-02, Vol.12 (1), p.97-109

2017

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The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies

Phosphatidylinositol 3-Kinase Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma

Exon array analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer

Sympathetic restraint of respiratory sinus arrhythmia: implications for vagal-cardiac tone assessment in humans

Molecular profiles and clinical outcome of stage UICC II colon cancer patients

Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma

Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM

Abstract 2606: Biological interpretation of circulating miRNA biomarkers predicting regorafenib clinical benefit in patients with hepatocellular carcinoma (HCC) in the RESORCE trial

Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study

Controlled breathing protocols probe human autonomic cardiovascular rhythms

Abstract 1798: A detailed comparison between second-generation AR antagonists reveals differences in the overall impact on gene regulation patterns in prostate cancer cells

EXTH-38. VELCRIN MOLECULAR GLUES INDUCE CELL DEATH IN GLIOBLASTOMAS WITH HIGH PDE3A AND SLFN12 EXPRESSION

Abstract 5036: Correlation of preclinical antitumor activity of regorafenib in CRC-PDX xenografts with gene expression and clinical parameters of the primary tumor

Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

Abstract 3599: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of colorectal carcinomas

Exploratory biomarker analyses of the single-arm, phase 2 study of regorafenib plus nivolumab in patients (pts) with mismatch repair-proficient (pMMR)/microsatellite stable (MSS) colorectal cancer (CRC)

Key factors for successful data integration in biomarker research

Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

Abstract 929: Tumor genotyping in the phase III GRID study of regorafenib vs placebo in tyrosine kinase inhibitor (TKI)-refractory GIST: Detection of KIT mutations in circulating tumor DNA comparing digital PCR and massive parallel sequencing

Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study

Abstract 3086: Inhibitors of the enzyme dihydroorotate dehydrogenase, overcome the differentiation blockade in acute myeloid leukemia

Abstract 2: Discovery of BAY 2402234 by phenotypic screening: A human Dihydroorotate Dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies

PPARδ Enhances Keratinocyte Proliferation in Psoriasis and Induces Heparin-Binding EGF-Like Growth Factor

Precompetitive activity to address the biological data needs of drug discovery

Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer

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