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How neutrophils kill microbes

Annual review of immunology, 2005-01, Vol.23 (1), p.197-223

Segal, Anthony W

2005

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Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1 and has consequences for myeloperoxidase activity

PloS one, 2015-04, Vol.10 (4), p.e0125906-e0125906

2015

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The function of the NADPH oxidase of phagocytes and its relationship to other NOXs in plants, invertebrates, and mammals

The international journal of biochemistry & cell biology, 2008, Vol.40 (4), p.604-618

Segal, Anthony W.

2008

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NADPH oxidases as electrochemical generators to produce ion fluxes and turgor in fungi, plants and humans

Open biology, 2016-05, Vol.6 (5), p.160028

Segal, Anthony W.

2016

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Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

The New England journal of medicine, 2009-11, Vol.361 (21), p.2033-2045

2009

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The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals

mBio, 2017-09, Vol.8 (5)

2017

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Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

The Journal of experimental medicine, 2009-08, Vol.206 (9), p.1883-1897

2009

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Variations in the Phagosomal Environment of Human Neutrophils and Mononuclear Phagocyte Subsets

Frontiers in immunology, 2019-03, Vol.10, p.188-188

2019

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Inflammatory Bowel Disease in CGD Reproduces the Clinicopathological Features of Crohn's Disease

The American journal of gastroenterology, 2009-01, Vol.104 (1), p.117-124

2009

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Making sense of the cause of Crohn's - a new look at an old disease [version 2; peer review: 2 approved]

F1000 research, 2016, Vol.5, p.2510-2510

Segal, Anthony W

2016

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Defective acute inflammation in Crohn's disease: a clinical investigation

The Lancet (British edition), 2006-02, Vol.367 (9511), p.668-678

2006

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The immunopathogenesis of Crohn's disease: a three-stage model

Current opinion in immunology, 2009-10, Vol.21 (5), p.506-513

2009

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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients

Nature communications, 2023-04, Vol.14 (1), p.2256-12, Article 2256

2023

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The role of neutrophils in the pathogenesis of Crohn's disease

European journal of clinical investigation, 2018-11, Vol.48 (S2), p.e12983-n/a

Segal, Anthony W.

2018

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Killing activity of neutrophils is mediated through activation of proteases by K + flux

Nature (London), 2002-03, Vol.416 (6878), p.291-297

2002

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Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

Disease models & mechanisms, 2015-08, Vol.8 (8), p.817-829

2015

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Mice Lacking Neutrophil Elastase Are Resistant to Bleomycin-Induced Pulmonary Fibrosis

The American journal of pathology, 2007, Vol.170 (1), p.65-74

2007

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Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation

Journal of Crohn's and colitis, 2016-12, Vol.10 (12), p.1417-1427

2016

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Impaired Immunity and Enhanced Resistance to Endotoxin in the Absence of Neutrophil Elastase and Cathepsin G

Immunity (Cambridge, Mass.), 2000-02, Vol.12 (2), p.201-210

2000

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ZODET: software for the identification, analysis and visualisation of outlier genes in microarray expression data

PloS one, 2014-01, Vol.9 (1), p.e81123-e81123

2014

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Corrigendum: An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils

Frontiers in pharmacology, 2017-10, Vol.8, p.728-728

2017

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The LRRC8A Mediated "Swell Activated" Chloride Conductance Is Dispensable for Vacuolar Homeostasis in Neutrophils

Frontiers in pharmacology, 2017-05, Vol.8, p.262-262

2017

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Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

Science translational medicine, 2018-01, Vol.10 (423)

2018

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The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems

BBA - Bioenergetics, 2004-06, Vol.1657 (1), p.1-22

2004

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Subproteome analysis of the neutrophil cytoskeleton

Proteomics (Weinheim), 2009-04, Vol.9 (7), p.2037-2049

2009

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How neutrophils kill microbes

Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1 and has consequences for myeloperoxidase activity

The function of the NADPH oxidase of phagocytes and its relationship to other NOXs in plants, invertebrates, and mammals

NADPH oxidases as electrochemical generators to produce ion fluxes and turgor in fungi, plants and humans

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

Variations in the Phagosomal Environment of Human Neutrophils and Mononuclear Phagocyte Subsets

Inflammatory Bowel Disease in CGD Reproduces the Clinicopathological Features of Crohn's Disease

Making sense of the cause of Crohn's - a new look at an old disease [version 2; peer review: 2 approved]

Defective acute inflammation in Crohn's disease: a clinical investigation

The immunopathogenesis of Crohn's disease: a three-stage model

Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients

The role of neutrophils in the pathogenesis of Crohn's disease

Killing activity of neutrophils is mediated through activation of proteases by K + flux

Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

Mice Lacking Neutrophil Elastase Are Resistant to Bleomycin-Induced Pulmonary Fibrosis

Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation

Impaired Immunity and Enhanced Resistance to Endotoxin in the Absence of Neutrophil Elastase and Cathepsin G

ZODET: software for the identification, analysis and visualisation of outlier genes in microarray expression data

Corrigendum: An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils

The LRRC8A Mediated "Swell Activated" Chloride Conductance Is Dispensable for Vacuolar Homeostasis in Neutrophils

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems

Subproteome analysis of the neutrophil cytoskeleton

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