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The efficacy and safety of amifostine for the acute radiation syndrome

Expert opinion on drug safety, 2019-11, Vol.18 (11), p.1077-1090

2019

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A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures

International journal of radiation biology, 2017-09, Vol.93 (9), p.851-869

2017

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How necessary are animal models for modern drug discovery?

Expert opinion on drug discovery, 2021-12, Vol.16 (12), p.1391-1397

2021

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Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): A review

Cytokine (Philadelphia, Pa.), 2015-01, Vol.71 (1), p.22-37

2015

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Repurposing Pharmaceuticals Previously Approved by Regulatory Agencies to Medically Counter Injuries Arising Either Early or Late Following Radiation Exposure

Frontiers in pharmacology, 2021-05, Vol.12

2021

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Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures

Journal of radiation research, 2013-11, Vol.54 (6), p.973-988

2013

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Analysis of the metabolomic profile in serum of irradiated nonhuman primates treated with Ex-Rad, a radiation countermeasure

Scientific reports, 2021-06, Vol.11 (1), p.11449-11449, Article 11449

2021

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Pathology of acute sub-lethal or near-lethal irradiation of nonhuman primates prophylaxed with the nutraceutical, gamma tocotrienol

Scientific reports, 2024-06, Vol.14 (1), p.13315-20

2024

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Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol

Scientific reports, 2024-03, Vol.14 (1), p.5757-5757, Article 5757

2024

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Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure

PloS one, 2014-11, Vol.9 (11), p.e114078-e114078

2014

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Radiation countermeasures for hematopoietic acute radiation syndrome: growth factors, cytokines and beyond

International journal of radiation biology, 2021-11, Vol.97 (11), p.1526-1547

2021

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Pharmacological management of ionizing radiation injuries: current and prospective agents and targeted organ systems

Expert opinion on pharmacotherapy, 2020-02, Vol.21 (3), p.317-337

2020

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A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part II. Countermeasures for limited indications, internalized radionuclides, emesis, late effects, and agents demonstrating efficacy in large animals with or without FDA IND status

International journal of radiation biology, 2017-09, Vol.93 (9), p.870-884

2017

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Alterations in Tissue Metabolite Profiles with Amifostine-Prophylaxed Mice Exposed to Gamma Radiation

Metabolites, 2020-05, Vol.10 (5), p.211

2020

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Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: current status and future perspectives

Expert opinion on investigational drugs, 2023-01, Vol.32 (1), p.25-35

2023

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The potential value of 5-androstenediol in countering acute radiation syndrome

Drug discovery today, 2024-02, Vol.29 (2), p.103856-103856, Article 103856

2024

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Entolimod as a radiation countermeasure for acute radiation syndrome

Drug discovery today, 2021-01, Vol.26 (1), p.17-30

2021

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BIO 300: a promising radiation countermeasure under advanced development for acute radiation syndrome and the delayed effects of acute radiation exposure

Expert opinion on investigational drugs, 2020-05, Vol.29 (5), p.429-441

2020

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An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned

International journal of radiation biology, 2016-02, Vol.92 (2), p.59-70

2016

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New pharmaceutical-based strategies that foster the development and promulgation of globally effective medical countermeasures for radiation exposure injuries

Expert opinion on pharmacotherapy, 2024-08, Vol.25 (12), p.1-1583

2024

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Radiation protectants: current status and future prospects

Health physics (1958), 2005-11, Vol.89 (5), p.531-545

Seed, Thomas M

2005

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Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice

Journal of radiation research, 2012-07, Vol.53 (4), p.526-536

2012

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Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: current status and future perspectives

Expert review of molecular diagnostics, 2021-07, Vol.21 (7), p.641-654

2021

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Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions

Expert review of proteomics, 2023-10, Vol.20 (10), p.221-246

2023

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The efficacy and safety of amifostine for the acute radiation syndrome

A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures

How necessary are animal models for modern drug discovery?

Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): A review

Repurposing Pharmaceuticals Previously Approved by Regulatory Agencies to Medically Counter Injuries Arising Either Early or Late Following Radiation Exposure

Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures

Analysis of the metabolomic profile in serum of irradiated nonhuman primates treated with Ex-Rad, a radiation countermeasure

Pathology of acute sub-lethal or near-lethal irradiation of nonhuman primates prophylaxed with the nutraceutical, gamma tocotrienol

Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol

Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure

Radiation countermeasures for hematopoietic acute radiation syndrome: growth factors, cytokines and beyond

Pharmacological management of ionizing radiation injuries: current and prospective agents and targeted organ systems

A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part II. Countermeasures for limited indications, internalized radionuclides, emesis, late effects, and agents demonstrating efficacy in large animals with or without FDA IND status

Alterations in Tissue Metabolite Profiles with Amifostine-Prophylaxed Mice Exposed to Gamma Radiation

Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: current status and future perspectives

The potential value of 5-androstenediol in countering acute radiation syndrome

Entolimod as a radiation countermeasure for acute radiation syndrome

BIO 300: a promising radiation countermeasure under advanced development for acute radiation syndrome and the delayed effects of acute radiation exposure

Models for Evaluating Agents Intended for the Prophylaxis, Mitigation and Treatment of Radiation Injuries Report of an NCI Workshop, December 3–4, 2003

An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned

New pharmaceutical-based strategies that foster the development and promulgation of globally effective medical countermeasures for radiation exposure injuries

Radiation protectants: current status and future prospects

Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice

Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: current status and future perspectives

Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions

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