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Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase

Cell metabolism, 2012-05, Vol.15 (5), p.691-702

2012

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FAM83B mediates EGFR- and RAS-driven oncogenic transformation

The Journal of clinical investigation, 2012-09, Vol.122 (9), p.3197-3210

2012

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Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple acyl-CoA dehydrogenase deficiency

PLoS genetics, 2013-06, Vol.9 (6), p.e1003563-e1003563

2013

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Design, Synthesis, and Biological Evaluation of Halogenated N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: Discovery of an Isoform-Selective Small Molecule Phospholipase D2 Inhibitor

Journal of medicinal chemistry, 2010-09, Vol.53 (18), p.6706-6719

2010

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Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (7), p.1916-1920

2009

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Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease

Brain (London, England : 1878), 2008-03, Vol.131 (3), p.630-641

2008

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Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

Nature chemical biology, 2009-02, Vol.5 (2), p.108-117

2009

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Phospholipase D Facilitates Efficient Entry of Influenza Virus, Allowing Escape from Innate Immune Inhibition

The Journal of biological chemistry, 2014-09, Vol.289 (37), p.25405-25417

2014

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Development of Dual PLD1/2 and PLD2 Selective Inhibitors from a Common 1,3,8-Triazaspiro[4.5]decane Core: Discovery of ML298 and ML299 That Decrease Invasive Migration in U87-MG Glioblastoma Cells

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2695-2699

2013

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Isoform selective PLD inhibition by novel, chiral 2,8-diazaspiro[4.5]decan-1-one derivatives

Bioorganic & medicinal chemistry letters, 2018-12, Vol.28 (23-24), p.3670-3673

2018

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Chemical modulation of glycerolipid signaling and metabolic pathways

Biochimica et biophysica acta, 2014-08, Vol.1841 (8), p.1060-1084

2014

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Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes

ACS chemical biology, 2015-02, Vol.10 (2), p.421-432

2015

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Regulation of Phospholipase D Activity and Phosphatidic Acid Production after Purinergic (P2Y6) Receptor Stimulation

The Journal of biological chemistry, 2013-07, Vol.288 (28), p.20477-20487

2013

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Crosscurrents in Australian First Nations and Non-Indigenous Art

1, 2024

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Further evaluation of novel structural modifications to scaffolds that engender PLD isoform selective inhibition

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (24), p.5553-5557

2014

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Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2240-2243

2009

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Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad-Spectrum Antiviral Activity against Influenza Strains

ChemMedChem, 2014-12, Vol.9 (12), p.2633-2637

2014

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Context-Dependent Substrate Recognition by Protein Farnesyltransferase

Biochemistry (Easton), 2009-03, Vol.48 (8), p.1691-1701

2009

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Back Cover: Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad-Spectrum Antiviral Activity against Influenza Strains (ChemMedChem 12/2014)

ChemMedChem, 2014-12, Vol.9 (12), p.2820-2820

2014

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Synthesis and evaluation of 3- and 7-substituted geranylgeranyl pyrophosphate analogs

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1889-1892

2008

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Combinatorial Modulation of Protein Prenylation

ACS chemical biology, 2007-06, Vol.2 (6), p.385-389

2007

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Synthesis, Biochemical, and Cellular Evaluation of Farnesyl Monophosphate Prodrugs as Farnesyltransferase Inhibitors

Journal of medicinal chemistry, 2007-07, Vol.50 (14), p.3274-3282

2007

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Evaluation of protein farnesyltransferase substrate specificity using synthetic peptide libraries

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5548-5551

2007

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Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B

Oncogene, 2014-06, Vol.33 (25), p.3298-3306

2014

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Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple Acyl-CoA dehydrogenase deficiency

PLoS genetics, 2013-06, Vol.9 (6)

2013

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Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase

FAM83B mediates EGFR- and RAS-driven oncogenic transformation

Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple acyl-CoA dehydrogenase deficiency

Design, Synthesis, and Biological Evaluation of Halogenated N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: Discovery of an Isoform-Selective Small Molecule Phospholipase D2 Inhibitor

Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity

Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease

Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

Phospholipase D Facilitates Efficient Entry of Influenza Virus, Allowing Escape from Innate Immune Inhibition

Development of Dual PLD1/2 and PLD2 Selective Inhibitors from a Common 1,3,8-Triazaspiro[4.5]decane Core: Discovery of ML298 and ML299 That Decrease Invasive Migration in U87-MG Glioblastoma Cells

Isoform selective PLD inhibition by novel, chiral 2,8-diazaspiro[4.5]decan-1-one derivatives

Chemical modulation of glycerolipid signaling and metabolic pathways

Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes

Regulation of Phospholipase D Activity and Phosphatidic Acid Production after Purinergic (P2Y6) Receptor Stimulation

Crosscurrents in Australian First Nations and Non-Indigenous Art

Further evaluation of novel structural modifications to scaffolds that engender PLD isoform selective inhibition

Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity

Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad-Spectrum Antiviral Activity against Influenza Strains

Context-Dependent Substrate Recognition by Protein Farnesyltransferase

Back Cover: Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad-Spectrum Antiviral Activity against Influenza Strains (ChemMedChem 12/2014)

Synthesis and evaluation of 3- and 7-substituted geranylgeranyl pyrophosphate analogs

Combinatorial Modulation of Protein Prenylation

Synthesis, Biochemical, and Cellular Evaluation of Farnesyl Monophosphate Prodrugs as Farnesyltransferase Inhibitors

Evaluation of protein farnesyltransferase substrate specificity using synthetic peptide libraries

Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B

Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple Acyl-CoA dehydrogenase deficiency

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