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Threshold-awareness in adaptive cancer therapy

PLoS computational biology, 2024-06, Vol.20 (6), p.e1012165

2024

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Antibiotic collateral sensitivity is contingent on the repeatability of evolution

Nature communications, 2019-01, Vol.10 (1), p.334-334, Article 334

2019

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A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study

The lancet oncology, 2017-02, Vol.18 (2), p.202-211

2017

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Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma

PLoS computational biology, 2021-10, Vol.17 (10), p.e1008755-e1008755

2021

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The Damaging Effect of Passenger Mutations on Cancer Progression

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (18), p.4763-4772

2017

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Evolution-Informed Strategies for Combating Drug Resistance in Cancer

International journal of molecular sciences, 2023-04, Vol.24 (7), p.6738

2023

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Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

PLoS computational biology, 2015-09, Vol.11 (9), p.e1004493

2015

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Diverse mutant selection windows shape spatial heterogeneity in evolving populations

PLoS computational biology, 2024-02, Vol.20 (2), p.e1011878-e1011878

2024

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Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer

Scientific reports, 2017-04, Vol.7 (1), p.1232-9, Article 1232

2017

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Radiosensitivity of Lung Metastases by Primary Histology and Implications for Stereotactic Body Radiation Therapy Using the Genomically Adjusted Radiation Dose

Journal of thoracic oncology, 2018-08, Vol.13 (8), p.1121-1127

2018

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Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model

PLoS computational biology, 2016-01, Vol.12 (1), p.e1004712-e1004712

2016

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Evolutionary dynamics of incubation periods

eLife, 2017-12, Vol.6

2017

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Stability of scRNA-Seq Analysis Workflows is Susceptible to Preprocessing and is Mitigated by Regularized or Supervised Approaches

Evolutionary bioinformatics online, 2022, Vol.18, p.11769343221123050-11769343221123050

2022

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Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems

Journal of mathematical biology, 2023, Vol.86 (5), p.68-68, Article 68

2023

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UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic

PloS one, 2021-07, Vol.16 (7), p.e0241734-e0241734

2021

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Biomathematical Optimization of Radiation Therapy in the Era of Targeted Agents

International journal of radiation oncology, biology, physics, 2017-01, Vol.97 (1), p.13-17

2017

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UV-C tower for point-of-care decontamination of filtering facepiece respirators

American journal of infection control, 2021-04, Vol.49 (4), p.424-429

2021

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Neutrophil to lymphocyte ratio (NTLR) predicts local control and overall survival after stereotactic body radiotherapy (SBRT) in metastatic sarcoma

Scientific reports, 2023-11, Vol.13 (1), p.19256-19256, Article 19256

2023

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Optimizing adaptive cancer therapy: dynamic programming and evolutionary game theory

Proceedings of the Royal Society. B, Biological sciences, 2020-04, Vol.287 (1925), p.20192454-20192454

2020

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Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Scientific reports, 2021-01, Vol.11 (1), p.2520-2520, Article 2520

2021

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Strategies to Mitigate Chemotherapy and Radiation Toxicities That Affect Eating

Nutrients, 2021-12, Vol.13 (12), p.4397

2021

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Genomic identification of sarcoma radiosensitivity and the clinical implications for radiation dose personalization

Translational oncology, 2021-10, Vol.14 (10), p.101165-101165, Article 101165

2021

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Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients

Journal of translational medicine, 2021-04, Vol.19 (1), p.180-8, Article 180

2021

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Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature

NPJ precision oncology, 2023-04, Vol.7 (1), p.38-38, Article 38

2023

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Threshold-awareness in adaptive cancer therapy

Antibiotic collateral sensitivity is contingent on the repeatability of evolution

A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma

The Damaging Effect of Passenger Mutations on Cancer Progression

Evolution-Informed Strategies for Combating Drug Resistance in Cancer

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

Diverse mutant selection windows shape spatial heterogeneity in evolving populations

Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer

Radiosensitivity of Lung Metastases by Primary Histology and Implications for Stereotactic Body Radiation Therapy Using the Genomically Adjusted Radiation Dose

Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model

Evolutionary dynamics of incubation periods

Stability of scRNA-Seq Analysis Workflows is Susceptible to Preprocessing and is Mitigated by Regularized or Supervised Approaches

Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems

UV decontamination of personal protective equipment with idle laboratory biosafety cabinets during the COVID-19 pandemic

Biomathematical Optimization of Radiation Therapy in the Era of Targeted Agents

UV-C tower for point-of-care decontamination of filtering facepiece respirators

Neutrophil to lymphocyte ratio (NTLR) predicts local control and overall survival after stereotactic body radiotherapy (SBRT) in metastatic sarcoma

Optimizing adaptive cancer therapy: dynamic programming and evolutionary game theory

Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Strategies to Mitigate Chemotherapy and Radiation Toxicities That Affect Eating

Habitat escalated adaptive therapy (HEAT): a phase 2 trial utilizing radiomic habitat-directed and genomic-adjusted radiation dose (GARD) optimization for high-grade soft tissue sarcoma

Genomic identification of sarcoma radiosensitivity and the clinical implications for radiation dose personalization

Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients

Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature

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