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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

EMBO reports, 2006-10, Vol.7 (10), p.988-994

2006

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Crystal Structure of a Lipid G Protein—Coupled Receptor

Science (American Association for the Advancement of Science), 2012-02, Vol.335 (6070), p.851-855

2012

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Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus

PloS one, 2018-04, Vol.13 (4), p.e0193236-e0193236

2018

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A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

Biochemical journal, 2009-12, Vol.424 (3), p.335-345

2009

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Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death

Molecular cell, 2010-07, Vol.39 (2), p.184-195

2010

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

Cancer cell, 2004, Vol.5 (1), p.25-35

2004

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Dimer Formation Drives the Activation of the Cell Death Protease Caspase 9

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (25), p.14250-14255

2001

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Inhibitor of Apoptosis Proteins in Eukaryotic Evolution and Development: A Model of Thematic Conservation

Developmental cell, 2008-10, Vol.15 (4), p.497-508

2008

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Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate

Bioscience reports, 2014-04, Vol.34 (2), p.e00100

2014

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Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19499-19510

2008

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The Fas-FADD death domain complex structure unravels signalling by receptor clustering

Nature (London), 2009-02, Vol.457 (7232), p.1019-1022

2009

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XIAP is not required for human tumor cell survival in the absence of an exogenous death signal

BMC cancer, 2010-01, Vol.10 (1), p.11-11, Article 11

2010

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SerpinB6 is an Inhibitor of Kallikrein-8 in Keratinocytes

Journal of biochemistry (Tokyo), 2007-10, Vol.142 (4), p.435-442

2007

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The contribution of NaV1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and NaV1.6 gain-of-function (GOF) mouse seizure control

British journal of pharmacology, 2024-06

2024

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What do people living in deprived communities in the UK think about household energy efficiency interventions?

Energy policy, 2014-03, Vol.66, p.335-349

2014

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Pharmacokinetic and Pharmacologic Characterization of the Dihydrotetrabenazine Isomers of Deutetrabenazine and Valbenazine

Clinical pharmacology in drug development, 2023-04, Vol.12 (4), p.447-456

2023

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Activation and Substrate Specificity of Caspase-14

Biochemistry (Easton), 2004-08, Vol.43 (32), p.10560-10569

2004

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XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs

The EMBO journal, 2005-02, Vol.24 (3), p.645-655

2005

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A Unified Model for Apical Caspase Activation

Molecular cell, 2003-02, Vol.11 (2), p.529-541

2003

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Caspase assays: identifying caspase activity and substrates in vitro and in vivo

Methods in enzymology, 2008, Vol.446, p.351-367

2008

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Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.51082

2004

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358 A Small Molecule S1P1 Receptor Agonist With Significant Efficacy in Animal Models of Inflammatory Bowel Disease (IBD)

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-84-S-84

2012

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Tu1616 Rpc1063 Is a Potent S1p1r Agonist With Efficacy in the Samp1yitfc Ileitis Model: New Evidence for Dysregulation of S1p Metabolism in Preclinical Models and Patients With Inflammatory Bowel Disease

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-807-S-807

2013

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Sa1221 Rpc1063, a Potent, Selective S1P1 Receptor Modulator, Is Active in a Therapeutic IBD Model and Exhibits Favorable PK/PD Properties in Healthy Volunteers

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-234-S-234

2013

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Natalia Kucirkova, Digital personalization in early childhood: Impact on childhood

Journal of early childhood literacy, 2019-12, p.146879841989573

Scott, Fiona L

2019

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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

Crystal Structure of a Lipid G Protein—Coupled Receptor

Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

Dimer Formation Drives the Activation of the Cell Death Protease Caspase 9

Inhibitor of Apoptosis Proteins in Eukaryotic Evolution and Development: A Model of Thematic Conservation

Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

The Fas-FADD death domain complex structure unravels signalling by receptor clustering

XIAP is not required for human tumor cell survival in the absence of an exogenous death signal

SerpinB6 is an Inhibitor of Kallikrein-8 in Keratinocytes

The contribution of NaV1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and NaV1.6 gain-of-function (GOF) mouse seizure control

What do people living in deprived communities in the UK think about household energy efficiency interventions?

Pharmacokinetic and Pharmacologic Characterization of the Dihydrotetrabenazine Isomers of Deutetrabenazine and Valbenazine

Activation and Substrate Specificity of Caspase-14

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs

A Unified Model for Apical Caspase Activation

Caspase assays: identifying caspase activity and substrates in vitro and in vivo

Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition

358 A Small Molecule S1P1 Receptor Agonist With Significant Efficacy in Animal Models of Inflammatory Bowel Disease (IBD)

Tu1616 Rpc1063 Is a Potent S1p1r Agonist With Efficacy in the Samp1yitfc Ileitis Model: New Evidence for Dysregulation of S1p Metabolism in Preclinical Models and Patients With Inflammatory Bowel Disease

Sa1221 Rpc1063, a Potent, Selective S1P1 Receptor Modulator, Is Active in a Therapeutic IBD Model and Exhibits Favorable PK/PD Properties in Healthy Volunteers

Natalia Kucirkova, Digital personalization in early childhood: Impact on childhood

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