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Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease

Cell metabolism, 2017-03, Vol.25 (3), p.713-726

2017

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rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs

The Journal of immunology (1950), 2018-04, Vol.200 (8), p.2542-2553

2018

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An Anti-VEGF-B Antibody Fragment Induces Regression of Pre-Existing Blood Vessels in the Rat Cornea

Investigative ophthalmology & visual science, 2017-07, Vol.58 (9), p.3404-3413

2017

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Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics

BMC biotechnology, 2018-03, Vol.18 (1), p.15-15, Article 15

2018

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The combination of ISCOMATRIX adjuvant and TLR agonists induces regression of established solid tumors in vivo

The Journal of immunology (1950), 2015-03, Vol.194 (5), p.2199-2207

2015

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A robust robotic high-throughput antibody purification platform

Journal of Chromatography A, 2016-07, Vol.1455, p.9-19

2016

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Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody

Cell reports (Cambridge), 2014-07, Vol.8 (2), p.410-419

2014

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Endogenous IL-11 Signaling Is Essential in Th2- and IL-13-Induced Inflammation and Mucus Production

American journal of respiratory cell and molecular biology, 2008-12, Vol.39 (6), p.739-746

2008

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The biology of vascular endothelial growth factor-B (VEGF-B)

Pulmonary pharmacology & therapeutics, 2006-01, Vol.19 (1), p.61-69

2006

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Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding

Journal of molecular biology, 2006-05, Vol.359 (1), p.76-85

2006

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Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment

Journal of molecular biology, 2008-12, Vol.384 (5), p.1203-1217

2008

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Transgenic Overexpression of Vascular Endothelial Growth Factor-B Isoforms by Endothelial Cells Potentiates Postnatal Vessel Growth In Vivo and In Vitro

Circulation research, 2005-09, Vol.97 (6), p.e60-e70

2005

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Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue

Journal of hepatology, 2023-05, Vol.78 (5), p.901-913

2023

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Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

Nature (London), 2012-10, Vol.490 (7420), p.426-430

2012

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Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362

Acta crystallographica. Section F, Structural biology communications, 2014-03, Vol.70 (3), p.358-361

2014

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Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions

Investigative ophthalmology & visual science, 2016-02, Vol.57 (2), p.586-591

2016

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Vascular Endothelial Growth Factor–B Blockade with CSL346 in Diabetic Kidney Disease: A Phase 2A Randomized Controlled Trial

Journal of the American Society of Nephrology, 2024-08

2024

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VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (15), p.6152-6157

2009

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Turn up the HEAT

Structure, 1999-05, Vol.7 (5), p.R91-R97

1999

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VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats

The Journal of clinical investigation, 2008-03, Vol.118 (3), p.913-923

2008

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An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry

Journal of virology, 2017-03, Vol.91 (5)

2017

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Identification of potent antagonist antibodies against mouse IL-13R alpha 1 using novel bioassays

Journal of immunological methods, 2014-05, Vol.407, p.48-57

2014

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Identification of potent antagonist antibodies against mouse IL-13Rα1 using novel bioassays

Journal of immunological methods, 2014-05, Vol.407, p.48-57

2014

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IL-11 Antagonist Inhibits Decidual Transformation Resulting in Pregnancy Failure in Mice

Biology of reproduction, 2008-05, Vol.78 (Suppl_1), p.190-191

2008

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Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs

An Anti-VEGF-B Antibody Fragment Induces Regression of Pre-Existing Blood Vessels in the Rat Cornea

Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics

The combination of ISCOMATRIX adjuvant and TLR agonists induces regression of established solid tumors in vivo

A robust robotic high-throughput antibody purification platform

Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody

Endogenous IL-11 Signaling Is Essential in Th2- and IL-13-Induced Inflammation and Mucus Production

The biology of vascular endothelial growth factor-B (VEGF-B)

Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding

Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment

Transgenic Overexpression of Vascular Endothelial Growth Factor-B Isoforms by Endothelial Cells Potentiates Postnatal Vessel Growth In Vivo and In Vitro

Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362

Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions

Vascular Endothelial Growth Factor–B Blockade with CSL346 in Diabetic Kidney Disease: A Phase 2A Randomized Controlled Trial

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

Turn up the HEAT

VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats

An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry

Identification of potent antagonist antibodies against mouse IL-13R alpha 1 using novel bioassays

Identification of potent antagonist antibodies against mouse IL-13Rα1 using novel bioassays

IL-11 Antagonist Inhibits Decidual Transformation Resulting in Pregnancy Failure in Mice

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