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The immunopathology of sepsis and potential therapeutic targets

Nature reviews. Immunology, 2017-07, Vol.17 (7), p.407-420

2017

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Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

JAMA : the journal of the American Medical Association, 2016-04, Vol.315 (14), p.1469

2016

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Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection

PLoS pathogens, 2021-04, Vol.17 (4), p.e1009491-e1009491

2021

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The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection

Frontiers in immunology, 2021-07, Vol.12, p.696280-696280

2021

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Resolving patient heterogeneity in critical illness requires multi-scale approaches

EBioMedicine, 2022-03, Vol.77, p.103918-103918, Article 103918

Scicluna, Brendon P.

2022

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Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single‐Blind, Parallel Group, Placebo Controlled Trial

Stem cells (Dayton, Ohio), 2018-11, Vol.36 (11), p.1778-1788

2018

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Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation

Respiratory research, 2022-06, Vol.23 (1), p.162-162, Article 162

2022

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Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients

PloS one, 2022-07, Vol.17 (7), p.e0271637-e0271637

2022

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High-dimensional analysis reveals an immune atlas and novel neutrophil clusters in the lungs of model animals with Actinobacillus pleuropneumoniae-induced pneumonia

Veterinary research (Paris), 2023-09, Vol.54 (1), p.76-16, Article 76

2023

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The Selective Sirtuin 1 Activator SRT2104 Reduces Endotoxin-Induced Cytokine Release and Coagulation Activation in Humans

Critical care medicine, 2015-06, Vol.43 (6), p.e199-e202

2015

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The leukocyte non-coding RNA landscape in critically ill patients with sepsis

eLife, 2020-12, Vol.9

2020

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Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia

Frontiers in immunology, 2020-05, Vol.11, p.796-796

2020

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Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

American journal of respiratory and critical care medicine, 2016-12, Vol.194 (11), p.1366-1374

2016

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The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis

Critical care (London, England), 2020-07, Vol.24 (1), p.423-423, Article 423

2020

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Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae -Evoked Pneumosepsis in Mice

Frontiers in immunology, 2021-03, Vol.12, p.600979

2021

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Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

Stem cells translational medicine, 2019-08, Vol.8 (8), p.785-796

2019

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Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications

BMC infectious diseases, 2024-03, Vol.24 (1), p.337-337, Article 337

2024

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Combined Transcriptome and Proteome Leukocyte's Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis

Frontiers in immunology, 2021-09, Vol.12, p.744799

2021

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An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration

Genome medicine, 2021-08, Vol.13 (1), p.131-131, Article 131

2021

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Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction

PLoS genetics, 2012-12, Vol.8 (12), p.e1003113-e1003113

2012

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The gut microbiota as a modulator of innate immunity during melioidosis

PLoS neglected tropical diseases, 2017-04, Vol.11 (4), p.e0005548-e0005548

2017

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Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy

The Journal of experimental medicine, 2009-08, Vol.206 (8), p.1787-1802

2009

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Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?

Critical care (London, England), 2019-06, Vol.23 (1), p.226-226, Article 226

2019

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Protease‐activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma

Molecular oncology, 2021-11, Vol.15 (11), p.3091-3108

2021

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The Adhesion G Protein-Coupled Receptor GPR97/ ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions

Frontiers in immunology, 2018-12, Vol.9, p.2830-2830

2018

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The immunopathology of sepsis and potential therapeutic targets

Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection

The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection

Resolving patient heterogeneity in critical illness requires multi-scale approaches

Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single‐Blind, Parallel Group, Placebo Controlled Trial

Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation

Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients

High-dimensional analysis reveals an immune atlas and novel neutrophil clusters in the lungs of model animals with Actinobacillus pleuropneumoniae-induced pneumonia

The Selective Sirtuin 1 Activator SRT2104 Reduces Endotoxin-Induced Cytokine Release and Coagulation Activation in Humans

The leukocyte non-coding RNA landscape in critically ill patients with sepsis

Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia

Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis

Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae -Evoked Pneumosepsis in Mice

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications

Combined Transcriptome and Proteome Leukocyte's Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis

An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration

Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction

The gut microbiota as a modulator of innate immunity during melioidosis

Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy

Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?

Protease‐activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma

The Adhesion G Protein-Coupled Receptor GPR97/ ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions

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