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A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells

Leukemia, 2016-11, Vol.30 (11), p.2187-2197

2016

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Follow the ATP: tumor energy production: a perspective

Anti-cancer agents in medicinal chemistry, 2014-01, Vol.14 (9), p.1187-1198

2014

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Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review

Translational oncology, 2012-04, Vol.5 (2), p.66-71

2012

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Two Case Reports of Resensitization to Previous Chemotherapy with the Novel Hypoxia-Activated Hypomethylating Anticancer Agent RRx-001 in Metastatic Colorectal Cancer Patients

Case reports in oncology, 2014-01, Vol.7 (1), p.79-85

2014

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The Scarlet Letter of Alkylation: A Mini Review of Selective Alkylating Agents

Translational oncology, 2012-08, Vol.5 (4), p.226-229

2012

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Partial Response to Platinum Doublets in Refractory EGFR-Positive Non-Small Cell Lung Cancer Patients after RRx-001: Evidence of Episensitization

Case reports in oncology, 2016-01, Vol.9 (1), p.62-67

2016

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Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome

Case reports in oncology, 2016-04, Vol.9 (1), p.246-248

2016

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The Case of a Zebra That Was Misdiagnosed as a Horse: Pulmonary Tumor Thrombotic Microangiopathy, a New Paraneoplastic Syndrome, Mimicking PD-1-Induced Pneumonitis

Case reports in oncology, 2016-01, Vol.9 (1), p.68-75

2016

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RRx-001-Induced Tumor Necrosis and Immune Cell Infiltration in an EGFR Mutation-Positive NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors: A Case Report

Case reports in oncology, 2016-01, Vol.9 (1), p.45-50

2016

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RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets

Case reports in oncology, 2016-03, Vol.9 (1), p.171-176

2016

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Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

Journal of medicinal chemistry, 1998-03, Vol.41 (6), p.787-797

1998

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Rapid one-pot preparation of 2-substituted benzimidazoles from 2-nitroanilines using microwave conditions

Tetrahedron letters, 2005-09, Vol.46 (39), p.6741-6743

2005

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Solid-phase reaction monitoring-Chemical derivatization and off-bead analysis

Biotechnology and bioengineering, 2000, Vol.71 (2), p.110-118

2000

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Analytical techniques for small molecule solid phase synthesis

Current medicinal chemistry, 2002-12, Vol.9 (23), p.2103-2127

2002

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Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Analytical chemistry (Washington), 2001-03, Vol.73 (5), p.963-970

2001

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Analytical Construct Resins for Analysis of Solid-Phase Chemistry

Chemistry : a European journal, 2002-04, Vol.8 (8), p.1768-1776

2002

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Beyond Antiangiogenesis: Vascular Modulation as an Anticancer Therapy—A Review

Translational oncology, 2012-06, Vol.5 (3), p.133-140

2012

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Episensitization: Defying Time's Arrow

Frontiers in oncology, 2015, Vol.5, p.134-134

2015

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Abstract 6381: NBS-1120: An e-NSAID with potent anti-cancer activity targets cell cycle proteins by generating polysulfides

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6381-6381

2020

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Application of ReactArray Robotics and Design of Experiments Techniques in Optimisation of Supported Reagent Chemistry

Organic process research & development, 2002-11, Vol.6 (6), p.823-825

2002

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Light-fluorous safety-catch arylgermanes - exceptionally robust, photochemically activated precursors for biaryl synthesis by Pd(0) catalysed cross-coupling

Chemical communications (Cambridge, England), 2007-01 (28), p.2926-2928

2007

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Abstract 2186: The novel nitric oxide and hydrogen sulfide releasing anti-cancer agent, NBS-1120, protects the GI tract from the ulcerogenic activity of aspirin and naproxen

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2186-2186

2019

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Reporter Resins for Solid-Phase Chemistry

Organic letters, 2001-02, Vol.3 (4), p.507-510

2001

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The solid phase synthesis of A series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor

Bioorganic & medicinal chemistry letters, 1998-12, Vol.8 (24), p.3609-3614

1998

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Preclinical Assessment of the Feasibility of Applying Controlled Release Oral Drug Delivery to a Lead Series of Atypical Antipsychotics

Journal of pharmaceutical sciences, 2006-04, Vol.95 (4), p.883-895

2006

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A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells

Follow the ATP: tumor energy production: a perspective

Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review

Two Case Reports of Resensitization to Previous Chemotherapy with the Novel Hypoxia-Activated Hypomethylating Anticancer Agent RRx-001 in Metastatic Colorectal Cancer Patients

The Scarlet Letter of Alkylation: A Mini Review of Selective Alkylating Agents

Partial Response to Platinum Doublets in Refractory EGFR-Positive Non-Small Cell Lung Cancer Patients after RRx-001: Evidence of Episensitization

Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome

The Case of a Zebra That Was Misdiagnosed as a Horse: Pulmonary Tumor Thrombotic Microangiopathy, a New Paraneoplastic Syndrome, Mimicking PD-1-Induced Pneumonitis

RRx-001-Induced Tumor Necrosis and Immune Cell Infiltration in an EGFR Mutation-Positive NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors: A Case Report

RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets

Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

Rapid one-pot preparation of 2-substituted benzimidazoles from 2-nitroanilines using microwave conditions

Solid-phase reaction monitoring-Chemical derivatization and off-bead analysis

Analytical techniques for small molecule solid phase synthesis

Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Analytical Construct Resins for Analysis of Solid-Phase Chemistry

Beyond Antiangiogenesis: Vascular Modulation as an Anticancer Therapy—A Review

Episensitization: Defying Time's Arrow

Abstract 6381: NBS-1120: An e-NSAID with potent anti-cancer activity targets cell cycle proteins by generating polysulfides

Application of ReactArray Robotics and Design of Experiments Techniques in Optimisation of Supported Reagent Chemistry

Light-fluorous safety-catch arylgermanes - exceptionally robust, photochemically activated precursors for biaryl synthesis by Pd(0) catalysed cross-coupling

Abstract 2186: The novel nitric oxide and hydrogen sulfide releasing anti-cancer agent, NBS-1120, protects the GI tract from the ulcerogenic activity of aspirin and naproxen

Reporter Resins for Solid-Phase Chemistry

The solid phase synthesis of A series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor

Preclinical Assessment of the Feasibility of Applying Controlled Release Oral Drug Delivery to a Lead Series of Atypical Antipsychotics

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