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Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

Molecular cancer therapeutics, 2018-11, Vol.17 (11), p.2285-2296

2018

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Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies

ChemMedChem, 2018-11, Vol.13 (21), p.2271-2280

2018

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Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179

ACS medicinal chemistry letters, 2022-03, Vol.13 (3), p.348-357

2022

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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Angewandte Chemie (International ed.), 2006-12, Vol.45 (47), p.7942-7948

2006

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Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.5010-5016

2000

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BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies

Human reproduction (Oxford), 2013-08, Vol.28 (8), p.2253-2264

2013

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Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3248-3248

2017

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Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1126-1126

2015

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Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018)

ChemMedChem, 2018-11, Vol.13 (21), p.2250-2250

2018

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Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.223-223

2016

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Abstract 4989: 3D spheroid screen yields SCD1 pathway inhibitors for the treatment of cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4989-4989

2017

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Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5301-5308

2008

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Abstract 317: 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.317-317

2015

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Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2682-2682

2022

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Inhibition of Proliferation and Fibrosis by Vitamin D Agonists—Impact for Uterine Leiomyoma

Biology of reproduction, 2011-07, Vol.85 (Suppl_1), p.363-363

2011

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Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system

The Journal of steroid biochemistry and molecular biology, 2009, Vol.113 (1), p.105-115

2009

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7α,15α-Ethano bridged steroids. Synthesis and progesterone receptor interaction

Tetrahedron, 1999-09, Vol.55 (37), p.11267-11274

1999

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Investigational developments for the treatment of progesterone-dependent diseases

Expert opinion on investigational drugs, 2008-04, Vol.17 (4), p.469-479

2008

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Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Synthesis (Stuttgart), 2005, Vol.2005 (2), p.301-305

2005

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SAGOPILONE, A NOVEL EPOTHILONE, INHIBITS TUMOR CELL GROWTH IN PRECLINICAL MODELS OF UROLOGICAL CANCER

The Journal of urology, 2008, Vol.179 (4), p.479-479

2008

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Beneficial effects of fluorine in the anti-progestin ZK 230211

Journal of fluorine chemistry, 2005-02, Vol.126 (2), p.217-220

2005

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Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Synthesis (Stuttgart), 2005-02, Vol.2005 (2), p.301-305

2005

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Cover Picture: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. Int. Ed. 47/2006)

Angewandte Chemie (International ed.), 2006-12, Vol.45 (47), p.7855-7855

2006

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Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development

Angewandte Chemie, 2006-12, Vol.118 (47), p.8110-8116

2006

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Titelbild: Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

Angewandte Chemie, 2006-12, Vol.118 (47), p.8019-8019

2006

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Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies

Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179

Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist

BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies

Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor

Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo

Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018)

Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy

Abstract 4989: 3D spheroid screen yields SCD1 pathway inhibitors for the treatment of cancer

Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Abstract 317: 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines

Inhibition of Proliferation and Fibrosis by Vitamin D Agonists—Impact for Uterine Leiomyoma

Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system

7α,15α-Ethano bridged steroids. Synthesis and progesterone receptor interaction

Investigational developments for the treatment of progesterone-dependent diseases

Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

SAGOPILONE, A NOVEL EPOTHILONE, INHIBITS TUMOR CELL GROWTH IN PRECLINICAL MODELS OF UROLOGICAL CANCER

Beneficial effects of fluorine in the anti-progestin ZK 230211

Efficient Chiral Pool Synthesis of the C1-C6 Fragment of Epothilones

Cover Picture: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. Int. Ed. 47/2006)

Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development

Titelbild: Total Synthesis and Antitumor Activity of ZK‐EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

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