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Sphingosine-1-phosphate: A Janus-faced mediator of fibrotic diseases

Biochimica et biophysica acta, 2013-01, Vol.1831 (1), p.239-250

2013

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Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1396

2020

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Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1407

2023

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Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction

The American journal of pathology, 2017-11, Vol.187 (11), p.2413-2429

2017

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The ceramide kinase inhibitor NVP‐231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death

British journal of pharmacology, 2014-12, Vol.171 (24), p.5829-5844

2014

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Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1240

2020

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Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2016-11, Vol.1861 (11), p.1840-1851

2016

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Sorafenib Treatment and Modulation of the Sphingolipid Pathway Affect Proliferation and Viability of Hepatocellular Carcinoma In Vitro

International journal of molecular sciences, 2020-03, Vol.21 (7), p.2409

2020

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Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks

Frontiers in pharmacology, 2016-06, Vol.7, p.167-167

2016

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Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells

International journal of molecular sciences, 2022-05, Vol.23 (11), p.5882

2022

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Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis

Cellular physiology and biochemistry, 2018-01, Vol.47 (6), p.2522-2533

2018

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Sphingosine 1-Phosphate Receptor 5 (S1P5) Knockout Ameliorates Adenine-Induced Nephropathy

International journal of molecular sciences, 2022-04, Vol.23 (7), p.3952, Article 3952

2022

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Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease

Biochimica et biophysica acta, 2014-07, Vol.1841 (7), p.1012-1020

2014

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Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants

International journal of molecular sciences, 2017-03, Vol.18 (3), p.595-595

2017

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Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice

Neuropharmacology, 2014-10, Vol.85, p.314-327

2014

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Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner

Biological chemistry, 2008-11, Vol.389 (11), p.1399-1407

2008

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Ceramide Kinase Contributes to Proliferation but not to Prostaglandin E2 Formation in Renal Mesangial Cells and Fibroblasts

Cellular physiology and biochemistry, 2014, Vol.34 (1), p.119-133

2014

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The contribution of the sphingosine 1-phosphate signaling pathway to chronic kidney diseases: recent findings and new perspectives

Pflügers Archiv, 2024-10

2024

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A role for plasma membrane Ca2+ ATPases in regulation of cellular Ca2+ homeostasis by sphingosine kinase-1

Pflügers Archiv, 2024-10

2024

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Targeting the Sphingosine Kinase/Sphingosine 1‐Phosphate Pathway to Treat Chronic Inflammatory Kidney Diseases

Basic & clinical pharmacology & toxicology, 2014-01, Vol.114 (1), p.44-49

2014

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Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis

Neuropharmacology, 2021-03, Vol.186, p.108464, Article 108464

2021

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Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice

Matrix biology, 2021-04, Vol.98, p.32-48

2021

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Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis

Cellular signalling, 2021-03, Vol.79, p.109881, Article 109881

2021

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Assessment of mitral valve leaflet perforation as a result of infective endocarditis by 3-dimensional real-time echocardiography

Journal of the American Society of Echocardiography, 2004-08, Vol.17 (8), p.919-922

2004

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Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2021-01, Vol.1866 (1), p.158821, Article 158821

2021

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Sphingosine-1-phosphate: A Janus-faced mediator of fibrotic diseases

Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt

Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols

Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction

The ceramide kinase inhibitor NVP‐231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death

Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge

Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation

Sorafenib Treatment and Modulation of the Sphingolipid Pathway Affect Proliferation and Viability of Hepatocellular Carcinoma In Vitro

Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks

Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells

Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis

Sphingosine 1-Phosphate Receptor 5 (S1P5) Knockout Ameliorates Adenine-Induced Nephropathy

Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease

Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants

Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice

Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner

Ceramide Kinase Contributes to Proliferation but not to Prostaglandin E2 Formation in Renal Mesangial Cells and Fibroblasts

The contribution of the sphingosine 1-phosphate signaling pathway to chronic kidney diseases: recent findings and new perspectives

A role for plasma membrane Ca2+ ATPases in regulation of cellular Ca2+ homeostasis by sphingosine kinase-1

Targeting the Sphingosine Kinase/Sphingosine 1‐Phosphate Pathway to Treat Chronic Inflammatory Kidney Diseases

Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis

Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice

Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis

Assessment of mitral valve leaflet perforation as a result of infective endocarditis by 3-dimensional real-time echocardiography

Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys

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