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Crystal structure of the human angiotensin-converting enzyme-lisinopril complex

Nature (London), 2003-01, Vol.421 (6922), p.551-554

2003

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Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme

Biochemistry (Easton), 2004-07, Vol.43 (27), p.8718-8724

2004

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Interkingdom Pharmacology of Angiotensin‑I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes

ACS medicinal chemistry letters, 2014-04, Vol.5 (4), p.346-351

2014

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Structural insights into the inhibitory mechanism of angiotensin‐I‐converting enzyme by the lactotripeptides IPP and VPP

FEBS letters, 2024-01, Vol.598 (2), p.242-251

2024

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Structural basis for the inhibition of human angiotensin‐1 converting enzyme by fosinoprilat

The FEBS journal, 2022-11, Vol.289 (21), p.6659-6671

2022

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Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

Scientific reports, 2012-10, Vol.2 (1), p.717-717, Article 717

2012

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Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb)

Biochemical journal, 2019-05, Vol.476 (10), p.1553-1570

2019

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N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.35685-35693

2010

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The effect of structural motifs on the ectodomain shedding of human angiotensin-converting enzyme

Biochemical and biophysical research communications, 2016-12, Vol.481 (1-2), p.111-116

2016

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Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin‐I converting enzyme

The FEBS journal, 2014-02, Vol.281 (3), p.943-956

2014

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Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)

The Journal of biological chemistry, 2014-01, Vol.289 (3), p.1798-1814

2014

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Structural characterization of angiotensin I‐converting enzyme in complex with a selenium analogue of captopril

The FEBS journal, 2011-10, Vol.278 (19), p.3644-3650

2011

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Association of B2 Receptor Polymorphisms and ACE Activity With ACE Inhibitor–Induced Angioedema in Black and Mixed‐Race South Africans

The journal of clinical hypertension (Greenwich, Conn.), 2013-06, Vol.15 (6), p.413-419

2013

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The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

European journal of biochemistry, 2004-06, Vol.271 (12), p.2539-2547

2004

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Shedding the load of hypertension: the proteolytic processing of angiotensin-converting enzyme

SAMJ: South African Medical Journal, 2012-06, Vol.102 (6), p.461-464

2012

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The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme

Biological chemistry, 2008-09, Vol.389 (9), p.1153-1161

2008

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The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity

Biochemical journal, 2005-08, Vol.389 (Pt 3), p.739-744

2005

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Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties

Biological chemistry, 2006-08, Vol.387 (8), p.1043-1051

2006

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Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design

Journal of molecular biology, 2006-03, Vol.357 (3), p.964-974

2006

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Proteolytic Release of Membrane-Bound Angiotensin-Converting Enzyme: Role of the Juxtamembrane Stalk Sequence

Biochemistry (Easton), 1996-07, Vol.35 (29), p.9549-9559

1996

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Modulation of Juxtamembrane Cleavage (“Shedding”) of Angiotensin-Converting Enzyme by Stalk Glycosylation: Evidence for an Alternative Shedding Protease

Biochemistry (Easton), 1999-08, Vol.38 (32), p.10388-10397

1999

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Cleavage of Disulfide-Bridged Stalk Domains during Shedding of Angiotensin-Converting Enzyme Occurs at Multiple Juxtamembrane Sites

Biochemistry (Easton), 2001-12, Vol.40 (51), p.15624-15630

2001

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Phorbol Ester-Induced Juxtamembrane Cleavage of Angiotensin-Converting Enzyme Is Not Inhibited by a Stalk Containing Intrachain Disulfides

Biochemistry (Easton), 1998-11, Vol.37 (44), p.15449-15456

1998

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Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme

Biochemical journal, 2003-04, Vol.371 (Pt 2), p.437-442

2003

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Structural characterization of angiotensinI-converting enzyme in complex with a selenium analogue of captopril

The FEBS journal, 2011-10, Vol.278 (19), p.3644

2011

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Crystal structure of the human angiotensin-converting enzyme-lisinopril complex

Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme

Interkingdom Pharmacology of Angiotensin‑I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes

Structural insights into the inhibitory mechanism of angiotensin‐I‐converting enzyme by the lactotripeptides IPP and VPP

Structural basis for the inhibition of human angiotensin‐1 converting enzyme by fosinoprilat

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb)

N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407

The effect of structural motifs on the ectodomain shedding of human angiotensin-converting enzyme

Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin‐I converting enzyme

Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)

Structural characterization of angiotensin I‐converting enzyme in complex with a selenium analogue of captopril

Association of B2 Receptor Polymorphisms and ACE Activity With ACE Inhibitor–Induced Angioedema in Black and Mixed‐Race South Africans

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

Shedding the load of hypertension: the proteolytic processing of angiotensin-converting enzyme

The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme

The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity

Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties

Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design

Proteolytic Release of Membrane-Bound Angiotensin-Converting Enzyme: Role of the Juxtamembrane Stalk Sequence

Modulation of Juxtamembrane Cleavage (“Shedding”) of Angiotensin-Converting Enzyme by Stalk Glycosylation: Evidence for an Alternative Shedding Protease

Cleavage of Disulfide-Bridged Stalk Domains during Shedding of Angiotensin-Converting Enzyme Occurs at Multiple Juxtamembrane Sites

Phorbol Ester-Induced Juxtamembrane Cleavage of Angiotensin-Converting Enzyme Is Not Inhibited by a Stalk Containing Intrachain Disulfides

Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme

Structural characterization of angiotensinI-converting enzyme in complex with a selenium analogue of captopril

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