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Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo

Scientific reports, 2018-10, Vol.8 (1), p.14690-10, Article 14690

2018

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A Dominant Negative Human Peroxisome Proliferator-Activated Receptor (PPAR)α Is a Constitutive Transcriptional Corepressor and Inhibits Signaling through All PPAR Isoforms

Endocrinology (Philadelphia), 2005-04, Vol.146 (4), p.1871-1882

2005

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Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

Nature (London), 1997-03, Vol.386 (6623), p.360-366

1997

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The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

Cell, 1993-11, Vol.75 (3), p.567-578

1993

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Solution structure of the DNA-binding domain of the oestrogen receptor

Nature (London), 1990-11, Vol.348 (6300), p.458-461

1990

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Three Novel Mutations at Serine 314 in the Thyroid Hormone β Receptor Differentially Impair Ligand Binding in the Syndrome of Resistance to Thyroid Hormone1

Endocrinology (Philadelphia), 1999-12, Vol.140 (12), p.5901-5906

1999

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Limbs are moving: where are they going?

Trends in genetics, 1998-06, Vol.14 (6), p.229-235

1998

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Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the .beta.-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane

Biochemistry (Easton), 1988-09, Vol.27 (18), p.6733-6741

1988

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A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms

Endocrinology (Philadelphia), 2005-04, Vol.146 (4), p.1871-1882

2005

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Spezialisierte Stationen zur Behandlung von akut erkrankten geriatrischen Patienten mit zusätzlichen kognitiven Beeinträchtigungen in Deutschland

Zeitschrift für Gerontologie und Geriatrie, 2010, Vol.43 (4), p.249-253

2010

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Linkers made to measure

Nature structural biology, 1997-09, Vol.4 (9), p.680-683

1997

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The Steroid/Nuclear Receptors: From Three-Dimensional Structure to Complex Function

Vitamins and Hormones, 1994, Vol.49, p.1-47

1994

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Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy : A zinc-finger structure with a third strand of β-sheet

Journal of molecular biology, 1992-11, Vol.228 (2), p.637-651

1992

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Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Molecular cell, 2013-07, Vol.51 (1), p.57-67

2013

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Galactose metabolism in Zea mays root tissues observed by 31P-NMR spectroscopy

Plant science (Limerick), 1989, Vol.59 (1), p.11-23

1989

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The structure of the core NuRD repression complex provides insights into its interaction with chromatin

eLife, 2016-04, Vol.5, p.e13941-e13941

2016

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Targeting Class I Histone Deacetylases in a “Complex” Environment

Trends in pharmacological sciences (Regular ed.), 2017-04, Vol.38 (4), p.363-377

2017

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PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

Chemical communications (Cambridge, England), 2020-04, Vol.56 (32), p.4476-4479

2020

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In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010733-e1010733

2022

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The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Nature communications, 2020-06, Vol.11 (1), p.3252-3252, Article 3252

2020

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Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Nature communications, 2021-02, Vol.12 (1), p.819-17, Article 819

2021

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Nuclear hormone receptor co-repressors: Structure and function

Molecular and cellular endocrinology, 2012-01, Vol.348 (2), p.440-449

2012

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Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Nature communications, 2016-04, Vol.7 (1), p.11262-11262, Article 11262

2016

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A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations

Diabetes (New York, N.Y.), 2018-06, Vol.67 (6), p.1086-1092

2018

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Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

Nucleic acids research, 2015-02, Vol.43 (4), p.2033

2015

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Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo

A Dominant Negative Human Peroxisome Proliferator-Activated Receptor (PPAR)α Is a Constitutive Transcriptional Corepressor and Inhibits Signaling through All PPAR Isoforms

Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

Solution structure of the DNA-binding domain of the oestrogen receptor

Three Novel Mutations at Serine 314 in the Thyroid Hormone β Receptor Differentially Impair Ligand Binding in the Syndrome of Resistance to Thyroid Hormone1

Limbs are moving: where are they going?

Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the .beta.-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane

A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms

Spezialisierte Stationen zur Behandlung von akut erkrankten geriatrischen Patienten mit zusätzlichen kognitiven Beeinträchtigungen in Deutschland

Linkers made to measure

The Steroid/Nuclear Receptors: From Three-Dimensional Structure to Complex Function

Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy : A zinc-finger structure with a third strand of β-sheet

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Galactose metabolism in Zea mays root tissues observed by 31P-NMR spectroscopy

The structure of the core NuRD repression complex provides insights into its interaction with chromatin

Targeting Class I Histone Deacetylases in a “Complex” Environment

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Nuclear hormone receptor co-repressors: Structure and function

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations

Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

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