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Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

Cell, 2014-08, Vol.158 (5), p.1136-1147

2014

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Structure of the T. brucei kinetoplastid RNA editing substrate-binding complex core component, RESC5

PloS one, 2023-03, Vol.18 (3), p.e0282155

2023

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Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (18), p.4988-4993

2016

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HipBA-promoter structures reveal the basis of heritable multidrug tolerance

Nature (London), 2015-08, Vol.524 (7563), p.59-64

2015

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Bacterial plasmid partition machinery: a minimalist approach to survival

Current opinion in structural biology, 2012-02, Vol.22 (1), p.72-79

Schumacher, Maria A

2012

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Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding

Nature communications, 2023-11, Vol.14 (1), p.7239-7239, Article 7239

2023

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Molecular Basis for a Protein-Mediated DNA-Bridging Mechanism that Functions in Condensation of the E. coli Chromosome

Molecular cell, 2012-11, Vol.48 (4), p.560-571

2012

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Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA

Nucleic acids research, 2021-12, Vol.49 (21), p.12540-12555

2021

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ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD

Genes & development, 2022-05, Vol.36 (9-10), p.618-633

2022

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Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB

Science (American Association for the Advancement of Science), 2009-01, Vol.323 (5912), p.396-401

2009

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M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation

Nature communications, 2023-11, Vol.14 (1), p.7375-7375, Article 7375

2023

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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents

Nature communications, 2019-09, Vol.10 (1), p.4275-18, Article 4275

2019

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Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP

Nature communications, 2022-10, Vol.13 (1), p.5834-5834, Article 5834

2022

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Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis

PloS one, 2012-06, Vol.7 (6), p.e39185-e39185

2012

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SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10586-10591

2013

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Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation

Biochemical journal, 2008-05, Vol.412 (1), p.1-18

Schumacher, Maria A

2008

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Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

Nature communications, 2022-07, Vol.13 (1), p.3793-15, Article 3793

2022

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Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations

Nucleic acids research, 2021-04, Vol.49 (7), p.4155-4170

2021

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Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

Nature communications, 2024-02, Vol.15 (1), p.1153-14, Article 1153

2024

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Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis

Genes & development, 2015-02, Vol.29 (4), p.451-464

2015

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Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides

Molecular microbiology, 2015-09, Vol.97 (5), p.844-865

2015

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Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check

The EMBO journal, 2011-01, Vol.30 (1), p.154-164

2011

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The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex

Nucleic acids research, 2017-06, Vol.45 (11), p.6923-6933

2017

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Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (26), p.7148-7153

2016

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Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (26), p.11763-11768

2010

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Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

Structure of the T. brucei kinetoplastid RNA editing substrate-binding complex core component, RESC5

Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ

HipBA-promoter structures reveal the basis of heritable multidrug tolerance

Bacterial plasmid partition machinery: a minimalist approach to survival

Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding

Molecular Basis for a Protein-Mediated DNA-Bridging Mechanism that Functions in Condensation of the E. coli Chromosome

Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA

ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD

Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB

M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation

Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents

Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP

Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis

SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid

Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation

Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations

Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis

Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides

Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check

The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex

Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis

Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition

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