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Molecular basis for DarT ADP-ribosylation of a DNA base

Nature (London), 2021-08, Vol.596 (7873), p.597-602

2021

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Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Open biology, 2020-11, Vol.10 (11), p.200237-200237

2020

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Specificity of DNA ADP-Ribosylation Reversal by NADARs

Toxins, 2024-05, Vol.16 (5), p.208

2024

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Exploring protein hotspots by optimized fragment pharmacophores

Nature communications, 2021-05, Vol.12 (1), p.3201-10, Article 3201

2021

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Beyond protein modification: the rise of non-canonical ADP-ribosylation

Biochemical journal, 2022-02, Vol.479 (4), p.463-477

2022

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Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

Pathogens (Basel), 2023-02, Vol.12 (2), p.324

2023

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Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA

Computational and structural biotechnology journal, 2022-01, Vol.20, p.4337-4350

2022

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Aspartate aminotransferase of Rhizobium leguminosarum has extended substrate specificity and metabolizes aspartate to enable N2 fixation in pea nodules

Microbiology (Society for General Microbiology), 2024-07, Vol.170 (7)

2024

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Molecular basis for the reversible ADP-ribosylation of guanosine bases

Molecular cell, 2023-07, Vol.83 (13), p.2303-2315.e6

2023

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Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (2), p.e2212931120

2023

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Updated protein domain annotation of the PARP protein family sheds new light on biological function

Nucleic acids research, 2023-08, Vol.51 (15), p.8217-8236

2023

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Author Correction: PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation

The EMBO journal, 2024-09

2024

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Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling

Molecular cell, 2023-05, Vol.83 (10), p.1743-1760.e11

2023

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Front Cover: Simultaneous Multiple MS Binding Assays Addressing D 1 and D 2 Dopamine Receptors (ChemMedChem 19/2017)

ChemMedChem, 2017-10, Vol.12 (19), p.1572-1572

2017

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PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation

The EMBO journal, 2024-07, Vol.43 (14), p.2929-2953

2024

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Deregulated DNA ADP-ribosylation impairs telomere replication

Nature structural & molecular biology, 2024-05, Vol.31 (5), p.791-800

2024

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Aspartate aminotransferase of Rhizobium leguminosarum has extended substrate specificity and metabolizes aspartate to enable N 2 fixation in pea nodules

Microbiology (Society for General Microbiology), 2024-07, Vol.170 (7)

2024

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Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV‑2 Macrodomain 1

Organic letters, 2024-07, Vol.26 (27), p.5700-5704

2024

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Corrigendum: Simultaneous Multiple MS Binding Assays Addressing D 1 and D 2 Dopamine Receptors

ChemMedChem, 2017-10, Vol.12 (20), p.1737-1737

2017

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Simultaneous Multiple MS Binding Assays Addressing D 1 and D 2 Dopamine Receptors

ChemMedChem, 2017-10, Vol.12 (19), p.1585-1594

2017

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Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B12 Trafficking

The Journal of biological chemistry, 2015-12, Vol.290 (49), p.29167-29177

2015

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Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (11), p.2965-2972

2018

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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

Science advances, 2021-04, Vol.7 (16)

2021

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Simultaneous Multiple MS Binding Assays Addressing D1 and D2 Dopamine Receptors

ChemMedChem, 2017-10, Vol.12 (19), p.1585-1594

2017

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Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14

ACS chemical biology, 2017-11, Vol.12 (11), p.2866-2874

2017

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Molecular basis for DarT ADP-ribosylation of a DNA base

Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Specificity of DNA ADP-Ribosylation Reversal by NADARs

Exploring protein hotspots by optimized fragment pharmacophores

Beyond protein modification: the rise of non-canonical ADP-ribosylation

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA

Aspartate aminotransferase of Rhizobium leguminosarum has extended substrate specificity and metabolizes aspartate to enable N2 fixation in pea nodules

Molecular basis for the reversible ADP-ribosylation of guanosine bases

Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2

Updated protein domain annotation of the PARP protein family sheds new light on biological function

Author Correction: PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation

Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling

Front Cover: Simultaneous Multiple MS Binding Assays Addressing D 1 and D 2 Dopamine Receptors (ChemMedChem 19/2017)

PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation

Deregulated DNA ADP-ribosylation impairs telomere replication

Aspartate aminotransferase of Rhizobium leguminosarum has extended substrate specificity and metabolizes aspartate to enable N 2 fixation in pea nodules

Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV‑2 Macrodomain 1

Corrigendum: Simultaneous Multiple MS Binding Assays Addressing D 1 and D 2 Dopamine Receptors

Simultaneous Multiple MS Binding Assays Addressing D 1 and D 2 Dopamine Receptors

Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B12 Trafficking

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

Simultaneous Multiple MS Binding Assays Addressing D1 and D2 Dopamine Receptors

Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14

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