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Role of ABCG2/BCRP in biology and medicine

Annual review of pharmacology and toxicology, 2006-01, Vol.46 (1), p.381-410

2006

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IDH1 and IDH2 mutations in pediatric acute leukemia

Leukemia, 2011-10, Vol.25 (10), p.1570-1577

2011

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Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells

Molecular pharmacology, 2002-12, Vol.62 (6), p.1321-1331

2002

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Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells

Molecular pharmacology, 1996-02, Vol.49 (2), p.311

1996

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Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.1011

1995

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6′,7′-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein

Clinical pharmacology and therapeutics, 1999-03, Vol.65 (3), p.237-244

1999

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ABCC4 Is a Determinant of Cytarabine‐Induced Cytotoxicity and Myelosuppression

Clinical and translational science, 2016-02, Vol.9 (1), p.51-59

2016

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Variability in human cytochrome P450 paclitaxel metabolism

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.566

1995

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P-Glycoprotein: A Major Determinant of Rifampicin-Inducible Expression of Cytochrome P4503A in Mice and Humans

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (9), p.4001-4005

1996

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Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

The Journal of clinical investigation, 1992-11, Vol.90 (5), p.1871-1878

1992

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The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme

The Journal of biological chemistry, 2004-06, Vol.279 (23), p.24218-24225

2004

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Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22250-22257

2004

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Nature medicine, 2001-09, Vol.7 (9), p.1028-1034

2001

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

Clinical pharmacology and therapeutics, 2001-08, Vol.70 (2), p.189-199

2001

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O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4

Molecular pharmacology, 1994-02, Vol.45 (2), p.352-358

1994

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Bcrp1 Gene Expression Is Required for Normal Numbers of Side Population Stem Cells in Mice, and Confers Relative Protection to Mitoxantrone in Hematopoietic Cells in vivo

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12339-12344

2002

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Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.39411-39418

2001

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A Single Point Mutation Leading to Loss of Catalytic Activity in Human Thiopurine S-Methyltransferase

Proceedings of the National Academy of Sciences - PNAS, 1995-02, Vol.92 (4), p.949-953

1995

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Regulation of human liver cytochromes P‐450 in family 3A in primary and continuous culture of human hepatocytes

Hepatology (Baltimore, Md.), 1993-11, Vol.18 (5), p.1254-1262

1993

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MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

Nature medicine, 1999-09, Vol.5 (9), p.1048-1051

1999

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Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate

The Journal of clinical investigation, 1996-01, Vol.97 (1), p.73-80

1996

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Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells

Molecular pharmacology, 1996-01, Vol.49 (1), p.63-72

1996

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Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta

The Journal of clinical investigation, 1993-08, Vol.92 (2), p.1018-1024

1993

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Paradoxical Transcriptional Activation of Rat Liver Cytochrome P-450 3A1 by Dexamethasone and the Antiglucocorticoid Pregnenolone 16α- Carbonitrile: Analysis by Transient Transfection into Primary Monolayer Cultures of Adult Rat Hepatocytes

Proceedings of the National Academy of Sciences - PNAS, 1992-03, Vol.89 (6), p.2145-2149

1992

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Mutant p53 Cooperates with ETS and Selectively Up-regulates Human MDR1 Not MRP1

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.39359-39367

2001

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Role of ABCG2/BCRP in biology and medicine

IDH1 and IDH2 mutations in pediatric acute leukemia

Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells

Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells

Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms

6′,7′-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein

ABCC4 Is a Determinant of Cytarabine‐Induced Cytotoxicity and Myelosuppression

Variability in human cytochrome P450 paclitaxel metabolism

P-Glycoprotein: A Major Determinant of Rifampicin-Inducible Expression of Cytochrome P4503A in Mice and Humans

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme

Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Identification of functionally variant MDR1 alleles among European Americans and African Americans

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4

Bcrp1 Gene Expression Is Required for Normal Numbers of Side Population Stem Cells in Mice, and Confers Relative Protection to Mitoxantrone in Hematopoietic Cells in vivo

Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450

A Single Point Mutation Leading to Loss of Catalytic Activity in Human Thiopurine S-Methyltransferase

Regulation of human liver cytochromes P‐450 in family 3A in primary and continuous culture of human hepatocytes

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate

Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells

Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta

Paradoxical Transcriptional Activation of Rat Liver Cytochrome P-450 3A1 by Dexamethasone and the Antiglucocorticoid Pregnenolone 16α- Carbonitrile: Analysis by Transient Transfection into Primary Monolayer Cultures of Adult Rat Hepatocytes

Mutant p53 Cooperates with ETS and Selectively Up-regulates Human MDR1 Not MRP1

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