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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Nature (London), 1998-05, Vol.393 (6683), p.382-386

1998

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A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Nature (London), 1999-04, Vol.398 (6727), p.518-522

1999

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A Presenilin Dimer at the Core of the γ-Secretase Enzyme: Insights from Parallel Analysis of Notch 1 and APP Proteolysis

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (22), p.13075-13080

2003

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Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1

Nature (London), 2000-06, Vol.405 (6789), p.966-970

2000

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Signalling downstream of activated mammalian Notch

Nature (London), 1995-09, Vol.377 (6547), p.355-358

1995

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Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina

Development (Cambridge), 2005-11, Vol.132 (22), p.5069-5079

2005

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A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

Molecular cell, 2000-02, Vol.5 (2), p.197-206

2000

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Expression of cytosolic peroxiredoxins in Plasmodium berghei ookinetes is regulated by environmental factors in the mosquito bloodmeal

PLoS pathogens, 2013-01, Vol.9 (1), p.e1003136-e1003136

2013

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Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3

Biochemical journal, 2001-09, Vol.358 (Pt 3), p.547-557

2001

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Signal Transduction by Activated mNotch: Importance of Proteolytic Processing and its Regulation by the Extracellular Domain

Proceedings of the National Academy of Sciences - PNAS, 1996-02, Vol.93 (4), p.1683-1688

1996

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Murine Notch Homologs (N1–4) Undergo Presenilin-dependent Proteolysis

The Journal of biological chemistry, 2001-10, Vol.276 (43), p.40268-40273

2001

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Ectodomain Shedding and Intramembrane Cleavage of Mammalian Notch Proteins Are Not Regulated through Oligomerization

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.50864-50873

2004

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γ-Secretase Inhibitors Repress Thymocyte Development

Proceedings of the National Academy of Sciences - PNAS, 2001-06, Vol.98 (13), p.7487-7491

2001

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Dietary flavonoids as potential neuroprotectants

Biological chemistry, 2002-03, Vol.383 (3-4), p.503-519

2002

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Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation

Biochemical journal, 2001-03, Vol.354 (Pt 3), p.493-500

2001

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Bioavailability of flavan-3-ols and procyanidins: gastrointestinal tract influences and their relevance to bioactive forms in vivo

Antioxidants & redox signaling, 2001-12, Vol.3 (6), p.1023-1039

2001

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Cone Survival Despite Rod Degeneration in XOPS-mCFP Transgenic Zebrafish

Investigative ophthalmology & visual science, 2005-12, Vol.46 (12), p.4762-4771

2005

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Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

The Journal of biological chemistry, 1999-12, Vol.274 (51), p.36801-36807

1999

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Laminar circuit formation in the vertebrate retina

Progress in Brain Research, 2005, Vol.147, p.155-169

2005

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(--)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (4), p.1024-1029

2006

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Cocoa flavanols alleviate early diastolic dysfunction by decreasing left atrial volume in healthy elderly individuals

European heart journal, 2024-10, Vol.45 (Supplement_1)

2024

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Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers

Journal of the American College of Cardiology, 2005-10, Vol.46 (7), p.1276-1283

2005

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Testing the race model inequality: an algorithm and computer programs

Behavior research methods, 2007-05, Vol.39 (2), p.291-302

2007

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(-)-Epicatechins promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade inflammation

Biochemical pharmacology, 2020, Vol.173

2020

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Uptake and metabolism of epicatechin and its access to the brain after oral ingestion

Free radical biology & medicine, 2002-12, Vol.33 (12), p.1693-1702

2002

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

A Presenilin Dimer at the Core of the γ-Secretase Enzyme: Insights from Parallel Analysis of Notch 1 and APP Proteolysis

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1

Signalling downstream of activated mammalian Notch

Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina

A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

Expression of cytosolic peroxiredoxins in Plasmodium berghei ookinetes is regulated by environmental factors in the mosquito bloodmeal

Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3

Signal Transduction by Activated mNotch: Importance of Proteolytic Processing and its Regulation by the Extracellular Domain

Murine Notch Homologs (N1–4) Undergo Presenilin-dependent Proteolysis

Ectodomain Shedding and Intramembrane Cleavage of Mammalian Notch Proteins Are Not Regulated through Oligomerization

γ-Secretase Inhibitors Repress Thymocyte Development

Dietary flavonoids as potential neuroprotectants

Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation

Bioavailability of flavan-3-ols and procyanidins: gastrointestinal tract influences and their relevance to bioactive forms in vivo

Cone Survival Despite Rod Degeneration in XOPS-mCFP Transgenic Zebrafish

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

Laminar circuit formation in the vertebrate retina

(--)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

Cocoa flavanols alleviate early diastolic dysfunction by decreasing left atrial volume in healthy elderly individuals

Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers

Testing the race model inequality: an algorithm and computer programs

(-)-Epicatechins promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade inflammation

Uptake and metabolism of epicatechin and its access to the brain after oral ingestion

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