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Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands

Molecular pharmacology, 1996-01, Vol.49 (1), p.1-6

1996

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Putative adverse outcome pathways relevant to neurotoxicity

Critical reviews in toxicology, 2015-01, Vol.45 (1), p.83-91

2015

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The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions

Journal of neuroimmunology, 2006-11, Vol.180 (1), p.71-87

2006

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Stem cell-based in vitro models as alternative methods for toxicity and efficacy tests in animals

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 2008-09, Vol.51 (9), p.1033

2008

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Proteomic surrogate biomarkers for in vitro testing of embryotoxicity: Quantitative differential investigation of ESC models

Toxicology letters, 2009-09, Vol.189, p.S31-S31

Schrattenholz, Andre

2009

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Differential and quantitative molecular analysis of ischemia complexity reduction by isotopic labeling of proteins using a neural embryonic stem cell model

Journal of the neurological sciences, 2005-03, Vol.229, p.261-267

2005

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The inflammatory transcriptome of reactive murine astrocytes and implications for their innate immune function

Journal of neurochemistry, 2006-02, Vol.96 (3), p.893-907

2006

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Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons

The Journal of pharmacology and experimental therapeutics, 1993-06, Vol.265 (3), p.1474

1993

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Monoclonal antibodies FK1 and WF6 define two neighboring ligand binding sites on Torpedo acetylcholine receptor alpha-polypeptide

The Journal of biological chemistry, 1994-04, Vol.269 (14), p.10407-10416

1994

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The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia‐ischemia as potently as erythropoietin

Journal of neurochemistry, 2004-11, Vol.91 (4), p.900-910

2004

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Synthesis, dopamine D2 receptor binding studies and docking analysis of 5-[3-(4-arylpiperazin-1-yl)propyl]-1H-benzimidazole, 5-[2-(4-arylpiperazin-1-yl)ethoxy]-1H-benzimidazole and their analogs

European journal of medicinal chemistry, 2005-05, Vol.40 (5), p.481-493

2005

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The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy

ALTEX : Alternativen zu Tierexperimenten, 2008, Vol.25 (3), p.163

2008

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Investigating the neuroprotective mechanism of action of a CDK5 inhibitor by phosphoproteome analysis

Journal of cellular biochemistry, 2005-07, Vol.95 (4), p.817-826

2005

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Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer’s disease

Behavioural brain research, 2000-08, Vol.113 (1), p.199-206

2000

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Minireview: Nicotinic Acetylcholine Receptors on Hippocampal Neurons: Distribution on the Neuronal Surface and Modulation of Receptor Activity

Journal of receptors and signal transduction, 1997, Vol.17 (1-3), p.243-266

1997

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Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function

The Journal of pharmacology and experimental therapeutics, 1997-03, Vol.280 (3), p.1117

1997

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Neuronal cell culture from human embryonic stem cells as in vitro model for neuroprotection

ALTEX : Alternativen zu Tierexperimenten, 2007, Vol.24 (1), p.9

2007

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Polyadenosine diphosphate-ribose polymerase (PARP) inhibition as a means of protecting the inner ear from cisplatin (CDDP)-mediated ototoxicity without affecting antitumor efficacy in vitro

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.e13501-e13501

2010

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Comparative Profiling of the Mammalian Mitochondrial Proteome: Multiple Aconitase-2 Isoforms Including N-formylkynurenine Modifications as Part of a Protein Biomarker Signature for Reactive Oxidative Species

Journal of proteome research, 2006-03, Vol.5 (3), p.625-633

2006

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Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/ΔF508-CFTR to the plasma membrane

Proteomics (Weinheim), 2004-12, Vol.4 (12), p.3833-3844

2004

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Neuregulin-1 receptor ErbB4 is upregulated in human midbrain dopaminergic neurons in Parkinson disease and in vitro Parkinson-models

Basal ganglia, 2013-03, Vol.3 (1), p.42-42

2013

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Neurotoxicity of active compounds--establishment of hESC-lines and proteomics technologies for human embryo- and neurotoxicity screening and biomarker identification

ALTEX, alternatives to animal experimentation, 2004, Vol.21 Suppl 3, p.41

2004

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Differential Radioactive Proteomic Analysis of Microdissected Renal Cell Carcinoma Tissue by 54 cm Isoelectric Focusing in Serial Immobilized pH Gradient Gels

Journal of proteome research, 2005-11, Vol.4 (6), p.2117-2125

2005

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Analysis of relative isotopologue abundances for quantitative profiling of complex protein mixtures labelled with the acrylamide/D 3 ‐acrylamide alkylation tag system

Rapid communications in mass spectrometry, 2003-06, Vol.17 (12), p.1283-1290

2003

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Physostigmine and Neuromuscular Transmission

Annals of the New York Academy of Sciences, 1993-06, Vol.681 (1), p.140-154

1993

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Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands

Putative adverse outcome pathways relevant to neurotoxicity

The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions

Stem cell-based in vitro models as alternative methods for toxicity and efficacy tests in animals

Proteomic surrogate biomarkers for in vitro testing of embryotoxicity: Quantitative differential investigation of ESC models

Differential and quantitative molecular analysis of ischemia complexity reduction by isotopic labeling of proteins using a neural embryonic stem cell model

The inflammatory transcriptome of reactive murine astrocytes and implications for their innate immune function

Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons

Monoclonal antibodies FK1 and WF6 define two neighboring ligand binding sites on Torpedo acetylcholine receptor alpha-polypeptide

The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia‐ischemia as potently as erythropoietin

Synthesis, dopamine D2 receptor binding studies and docking analysis of 5-[3-(4-arylpiperazin-1-yl)propyl]-1H-benzimidazole, 5-[2-(4-arylpiperazin-1-yl)ethoxy]-1H-benzimidazole and their analogs

The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy

Investigating the neuroprotective mechanism of action of a CDK5 inhibitor by phosphoproteome analysis

Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer’s disease

Minireview: Nicotinic Acetylcholine Receptors on Hippocampal Neurons: Distribution on the Neuronal Surface and Modulation of Receptor Activity

Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function

Neuronal cell culture from human embryonic stem cells as in vitro model for neuroprotection

Polyadenosine diphosphate-ribose polymerase (PARP) inhibition as a means of protecting the inner ear from cisplatin (CDDP)-mediated ototoxicity without affecting antitumor efficacy in vitro

Comparative Profiling of the Mammalian Mitochondrial Proteome: Multiple Aconitase-2 Isoforms Including N-formylkynurenine Modifications as Part of a Protein Biomarker Signature for Reactive Oxidative Species

Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/ΔF508-CFTR to the plasma membrane

Neuregulin-1 receptor ErbB4 is upregulated in human midbrain dopaminergic neurons in Parkinson disease and in vitro Parkinson-models

Neurotoxicity of active compounds--establishment of hESC-lines and proteomics technologies for human embryo- and neurotoxicity screening and biomarker identification

Differential Radioactive Proteomic Analysis of Microdissected Renal Cell Carcinoma Tissue by 54 cm Isoelectric Focusing in Serial Immobilized pH Gradient Gels

Analysis of relative isotopologue abundances for quantitative profiling of complex protein mixtures labelled with the acrylamide/D 3 ‐acrylamide alkylation tag system

Physostigmine and Neuromuscular Transmission

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