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Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.705-713

2016

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The Photo-Favorskii Reaction of p-Hydroxyphenacyl Compounds Is Initiated by Water-Assisted, Adiabatic Extrusion of a Triplet Biradical

Journal of the American Chemical Society, 2008-03, Vol.130 (11), p.3307-3309

2008

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The Crystal Structures of Klebsiella pneumoniae Acetolactate Synthase with Enzyme-bound Cofactor and with an Unusual Intermediate

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.2242-2253

2004

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How an Enzyme Surmounts the Activation Energy Barrier

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.11931-11932

Schowen, Richard L.

2003

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A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells

Pharmaceutical research, 2001-02, Vol.18 (2), p.171-176

2001

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Effect of ‘pH’ on the rate of asparagine deamidation in polymeric formulations: ‘pH’–rate profile

Journal of pharmaceutical sciences, 2001-02, Vol.90 (2), p.141-156

2001

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Racemization of an Asparagine Residue during Peptide Deamidation

Journal of the American Chemical Society, 2003-09, Vol.125 (38), p.11486-11487

2003

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Polyvinylpyrrolidone–drug conjugate: synthesis and release mechanism

Journal of controlled release, 2004-01, Vol.94 (1), p.91-100

2004

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Isotope effects and temperature dependences in the action of the glucose dehydrogenase of the mesophilic bacterium Bacillus megaterium

Journal of physical organic chemistry, 2013-12, Vol.26 (12), p.1066-1070

2013

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Heavy atom motions and tunneling in hydrogen transfer reactions: the importance of the pre-tunneling state

Journal of physical organic chemistry, 2010-07, Vol.23 (7), p.586-605

2010

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A Tribute to Ronald T. Borchardt—Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.370-385

2016

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Characterizing protein structure in amorphous solids using hydrogen/deuterium exchange with mass spectrometry

Analytical biochemistry, 2007-07, Vol.366 (1), p.18-28

2007

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The antiviral drug ribavirin is a selective inhibitor of S-adenosyl- l-homocysteine hydrolase from Trypanosoma cruzi

Bioorganic & medicinal chemistry, 2007-12, Vol.15 (23), p.7281-7287

2007

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The Trapping of a Spontaneously “Flipped-Out” Base from Double Helical Nucleic Acids by Host−Guest Complexation with β-Cyclodextrin: The Intrinsic Base-Flipping Rate Constant for DNA and RNA

Journal of the American Chemical Society, 2002-11, Vol.124 (47), p.14049-14053

2002

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Secondary Structure and Protein Deamidation

Journal of pharmaceutical sciences, 1999-01, Vol.88 (1), p.8-13

1999

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Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution

Proteins, structure, function, and bioinformatics, 2008-04, Vol.71 (1), p.131-143

2008

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Catalytic Strategy of S-Adenosyl-l-homocysteine Hydrolase: Transition-State Stabilization and the Avoidance of Abortive Reactions

Biochemistry (Easton), 2003-02, Vol.42 (7), p.1900-1909

2003

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Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 3. Role of Lysyl and Tyrosyl Residues of the C-Terminal Extension

Biochemistry (Easton), 2010-09, Vol.49 (38), p.8434-8441

2010

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Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 1. Basic Features of the Association and Dissociation Processes

Biochemistry (Easton), 2007-05, Vol.46 (19), p.5798-5809

2007

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Trehalose and calcium exert site-specific effects on calmodulin conformation in amorphous solids

Biotechnology and bioengineering, 2007-08, Vol.97 (6), p.1650-1653

2007

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Effects of Ligand Binding and Oxidation on Hinge-Bending Motions in S-Adenosyl-l-homocysteine Hydrolase

Biochemistry (Easton), 2006-06, Vol.45 (25), p.7778-7786

2006

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Isotopic and other studies on the molecular origins of substrate regulation of some pyruvate decarboxylases: a reconsideration

Isotopes in environmental and health studies, 2007-03, Vol.43 (1), p.1-16

Schowen, Richard L.

2007

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Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state

Journal of pharmaceutical sciences, 2005-03, Vol.94 (3), p.666-675

2005

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Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 2. The Role of Helix 18 Stability

Biochemistry (Easton), 2008-04, Vol.47 (17), p.4983-4991

2008

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Domain Motions and the Open-to-Closed Conformational Transition of an Enzyme: A Normal Mode Analysis of S-Adenosyl-l-homocysteine Hydrolase

Biochemistry (Easton), 2005-05, Vol.44 (19), p.7228-7239

2005

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Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide

The Photo-Favorskii Reaction of p-Hydroxyphenacyl Compounds Is Initiated by Water-Assisted, Adiabatic Extrusion of a Triplet Biradical

The Crystal Structures of Klebsiella pneumoniae Acetolactate Synthase with Enzyme-bound Cofactor and with an Unusual Intermediate

How an Enzyme Surmounts the Activation Energy Barrier

A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells

Effect of ‘pH’ on the rate of asparagine deamidation in polymeric formulations: ‘pH’–rate profile

Racemization of an Asparagine Residue during Peptide Deamidation

Polyvinylpyrrolidone–drug conjugate: synthesis and release mechanism

Isotope effects and temperature dependences in the action of the glucose dehydrogenase of the mesophilic bacterium Bacillus megaterium

Heavy atom motions and tunneling in hydrogen transfer reactions: the importance of the pre-tunneling state

A Tribute to Ronald T. Borchardt—Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man

Characterizing protein structure in amorphous solids using hydrogen/deuterium exchange with mass spectrometry

The antiviral drug ribavirin is a selective inhibitor of S-adenosyl- l-homocysteine hydrolase from Trypanosoma cruzi

The Trapping of a Spontaneously “Flipped-Out” Base from Double Helical Nucleic Acids by Host−Guest Complexation with β-Cyclodextrin: The Intrinsic Base-Flipping Rate Constant for DNA and RNA

Secondary Structure and Protein Deamidation

Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution

Catalytic Strategy of S-Adenosyl-l-homocysteine Hydrolase: Transition-State Stabilization and the Avoidance of Abortive Reactions

Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 3. Role of Lysyl and Tyrosyl Residues of the C-Terminal Extension

Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 1. Basic Features of the Association and Dissociation Processes

Trehalose and calcium exert site-specific effects on calmodulin conformation in amorphous solids

Effects of Ligand Binding and Oxidation on Hinge-Bending Motions in S-Adenosyl-l-homocysteine Hydrolase

Isotopic and other studies on the molecular origins of substrate regulation of some pyruvate decarboxylases: a reconsideration

Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state

Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 2. The Role of Helix 18 Stability

Domain Motions and the Open-to-Closed Conformational Transition of an Enzyme: A Normal Mode Analysis of S-Adenosyl-l-homocysteine Hydrolase

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