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Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid: Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent

Journal of medicinal chemistry, 2001-04, Vol.44 (8), p.1217-1230

2001

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Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity

Protein science, 1998-10, Vol.7 (10), p.2118-2126

1998

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Hair growth effects of oral administration of finasteride, a steroid 5α-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque

The journal of clinical endocrinology and metabolism, 1992-02, Vol.74 (2), p.345-350

1992

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Determination of dissociation constants of high affinity (pM) human renin inhibitors: application to analogs of ditekiren (U-71,038)

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2107-2112

1991

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Small Molecule Peptidomimetics Containing a Novel Phosphotyrosine Bioisostere Inhibit Protein Tyrosine Phosphatase 1B and Augment Insulin Action

Biochemistry (Easton), 2001-05, Vol.40 (19), p.5642-5654

2001

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Synthesis and Biological Activity of a Novel Class of Small Molecular Weight Peptidomimetic Competitive Inhibitors of Protein Tyrosine Phosphatase 1B

Journal of medicinal chemistry, 2002-01, Vol.45 (3), p.598-622

2002

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alpha.,.alpha.-Difluoro-.beta.-aminodeoxystatine-containing renin-inhibitory peptides

Journal of medicinal chemistry, 1987-10, Vol.30 (10), p.1837-1842

1987

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A stereospecific synthesis of 3-aminodeoxystatine

Journal of organic chemistry, 1988-07, Vol.53 (15), p.3628-3631

Schostarez, Heinrich J

1988

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Modification of the N-terminus of peptidomimetic protein tyrosine phosphatase 1B (PTP1B) inhibitors: identification of analogues with cellular activity

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (5), p.971-975

2003

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Potassium Channel Conductance: A Mechanism Affecting Hair Growth both In Vitro and In Vivo

Journal of investigative dermatology, 1992-03, Vol.98 (3), p.315-319

1992

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Structure-conformation-activity relationships of renin inhibitory peptides having P1-P'1Xaaψ[CH2NH]Yaa substitutions: molecular modeling and crystallography studies

Tetrahedron, 1988, Vol.44 (3), p.661-673

1988

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Nucleophilic Attack at Sulfoxide: The Methanethiol-Mediated Cleavage of a Thiane 1-Oxide

Journal of organic chemistry, 1996-11, Vol.61 (24), p.8701-8705

1996

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Guayule Rubber: Vulcanization Properties of Gum and Filled Stocks

Rubber chemistry and technology, 1977-11, Vol.50 (5), p.981-987

1977

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Cyanoguanidine bioisosteres in potassium channel openers: Evaluation of 3,4-disubstituted-1,2,5-thiadiazole-1-oxides

Bioorganic & medicinal chemistry letters, 1996-09, Vol.6 (18), p.2187-2192

1996

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Thermodynamics of the interaction of inhibitors with the binding site of recombinant human renin

Journal of medicinal chemistry, 1990-08, Vol.33 (8), p.2080-2086

1990

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Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque

The journal of clinical endocrinology and metabolism, 1992-02, Vol.74 (2), p.345-350

1992

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ChemInform Abstract: A Stereospecific Synthesis of 3‐Aminodeoxystatine

ChemInform, 1989-01, Vol.20 (3), p.no-no

SCHOSTAREZ, H. J.

1989

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ChemInform Abstract: Nucleophilic Attack at Sulfoxide: The Methanethiol-Mediated Cleavage of a Thiane 1-Oxide

ChemInform, 1997-04, Vol.28 (17), p.no-no

1997

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α,α-Difluoro-β-aminodeoxystatine-containing renin inhibitory peptide

Journal of medicinal chemistry, 1987, Vol.30 (10), p.1837-1842

1987

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Exploiting the molecular template of angiotensinogen in the discovery and design of peptidyl, pseudopeptidyl and peptidimimetic inhibitors of human renin: a structure-activity perspective

Advances in experimental medicine and biology, 1991, Vol.306, p.307

1991

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ChemInform Abstract: Cyanoguanidine Bioisosteres in Potassium Channel Openers: Evaluation of 3,4-Disubstituted-1,2,5-thiadiazole-1-oxides

ChemInform, 1997-01, Vol.28 (3), p.no-no

1997

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ChemInform Abstract: Structure‐Conformation‐Activity Relationships of Renin Inhibitory Peptides Having P1‐P1′ Xaaψ(CH2NH)Yaa Substitutions: Molecular Modeling and Crystallography Studies

ChemInform, 1988-06, Vol.19 (23), p.no-no

1988

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An experimental method for the determination of enzyme-competitive inhibitor dissociation constants from displacement curves: Application to human renin using fluorescence energy transfer to a synthetic dansylated inhibitor peptide

Analytical biochemistry, 1989-08, Vol.181 (1), p.172-181

1989

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HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs

International Journal of Peptide and Protein Research, 1992-09, Vol.40 (3-4), p.274-281

1992

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Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid: Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent

Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity

Hair growth effects of oral administration of finasteride, a steroid 5α-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque

Determination of dissociation constants of high affinity (pM) human renin inhibitors: application to analogs of ditekiren (U-71,038)

Small Molecule Peptidomimetics Containing a Novel Phosphotyrosine Bioisostere Inhibit Protein Tyrosine Phosphatase 1B and Augment Insulin Action

Synthesis and Biological Activity of a Novel Class of Small Molecular Weight Peptidomimetic Competitive Inhibitors of Protein Tyrosine Phosphatase 1B

alpha.,.alpha.-Difluoro-.beta.-aminodeoxystatine-containing renin-inhibitory peptides

A stereospecific synthesis of 3-aminodeoxystatine

Modification of the N-terminus of peptidomimetic protein tyrosine phosphatase 1B (PTP1B) inhibitors: identification of analogues with cellular activity

Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors

Potassium Channel Conductance: A Mechanism Affecting Hair Growth both In Vitro and In Vivo

Structure-conformation-activity relationships of renin inhibitory peptides having P1-P'1Xaaψ[CH2NH]Yaa substitutions: molecular modeling and crystallography studies

Nucleophilic Attack at Sulfoxide: The Methanethiol-Mediated Cleavage of a Thiane 1-Oxide

Guayule Rubber: Vulcanization Properties of Gum and Filled Stocks

Cyanoguanidine bioisosteres in potassium channel openers: Evaluation of 3,4-disubstituted-1,2,5-thiadiazole-1-oxides

Thermodynamics of the interaction of inhibitors with the binding site of recombinant human renin

Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque

ChemInform Abstract: A Stereospecific Synthesis of 3‐Aminodeoxystatine

ChemInform Abstract: Nucleophilic Attack at Sulfoxide: The Methanethiol-Mediated Cleavage of a Thiane 1-Oxide

α,α-Difluoro-β-aminodeoxystatine-containing renin inhibitory peptide

Exploiting the molecular template of angiotensinogen in the discovery and design of peptidyl, pseudopeptidyl and peptidimimetic inhibitors of human renin: a structure-activity perspective

ChemInform Abstract: Cyanoguanidine Bioisosteres in Potassium Channel Openers: Evaluation of 3,4-Disubstituted-1,2,5-thiadiazole-1-oxides

ChemInform Abstract: Structure‐Conformation‐Activity Relationships of Renin Inhibitory Peptides Having P1‐P1′ Xaaψ(CH2NH)Yaa Substitutions: Molecular Modeling and Crystallography Studies

An experimental method for the determination of enzyme-competitive inhibitor dissociation constants from displacement curves: Application to human renin using fluorescence energy transfer to a synthetic dansylated inhibitor peptide

HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs

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